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Campylobacter and Heliobacter
sweet
18
Accounting
Pre-School
02/24/2009

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Cards

Term
gram negative, curved bacilli; microaerophilic, antibiotic resistant, tiny, do not ferment and are non-halophilic
Definition
Campylobacter
Term
consumption of contaminated water/foods; gastroenteritis; young adults
Definition
campylobacter jejuni
Term
gastroenteritis, warm months, young adults
Definition
c. jejuni
Term
Acute diarrhea with blood and neutrophils in stool; destruction of mucosal surfaces
Definition
c. jejuni
Term
associated with guillan-barre syndrome, immune disorder of PNS
Definition
c. jejuni
Term
grows best under microaerophilic and thermophilic conditions (42C)
Definition
C. jejuni
Term
Treatment of C. jejuni
Definition
most self limiting but can give cipro for adults and erythromycin for children
Term
Campylobacter fetus
Definition
systemic bacteremia, often fatal, has S protein (capsule), grows at 37C
Term
gram-negative, microaerophilic, spiral bacteria, stomach pain
Definition
Heliobacter pylori
Term
gastric MALT b-cell lymphomas
Definition
H. pylori
Term
high infection rates for H. pylori correlate with:
Definition
poor sanitary conditions
Term
H. pylori colonization mechanisms
Definition
5/6 polar flagella, urease, attachment, and LPS
Term
Pathology of H. pylori
Definition
penetrates lamina propria w/ PMNs, alters mucosal epithelial glands, erosion/ulceration
Term
Heliobacter isolate that expresses VacA (forms vacuoles) and CagA (signal transduction pathway)
Definition
Type I strains
ALL duodenal ulcers are type I
Term
no VacA or CagA
Definition
Type II H. pylori
Term
virulence factors for H. pylori
Definition
urease, heat shock protein, acid-inhibitory protein, adhesins, mucinase, superoxide dismutase
Term
Main detection of heliobacter pylori
Definition
gastric biopsies
Term
Treatment of h. pylori
Definition
2 antibiotics, proton-pump inhibitor and bismuth salts
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