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Definition
1. The same pathogen is present in every case of the disease. 2. The pathogen must be isolated from the diseased host and grown in pure culture. 3. The pathogen from the pure culture must cause the disease when it is inoculated into a healthy, susceptible lab animal. 4. The pathogen must be isolated from the inoculated animal and must be shown to be the original organism. |
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subjective changes a patient experiences, e.g. malaise and pain |
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objective changes a physician can observe and measure e.g. fever |
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a specific group of symptoms or signs that always accompany a particular disease |
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any disease that spreads from one host to another, either directly or indirectly. e.g. chickenpox, measles, genital herpes, typhoid fever, tuberculosis |
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disease that is easily spread from one person to another e.g. chicken pox |
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any disease that is not spread from one host to another, e.g. tetanus |
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the number of people in a population who develop a disease during a particular time period; indicates how easily the disease is spread |
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the number of people in a population who develop a disease at a specified time, regardless of when it first appeared; includes old and new cases |
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– disease that occurs occasionally, e.g. typhoid fever in the USA |
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Definition
disease that is constantly present in a population e.g. common cold in the USA |
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if a number of people in a given area acquire a certain disease in a relatively short time period, e.g. influenza in January in the USA |
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Definition
an epidemic disease that occurs worldwide, e.g. influenza in 1918, AIDS now |
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Definition
disease that develops rapidly and lasts a short time, e.g. influenza |
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Definition
disease that develops more slowly, but whose effects may be continual or recurrent, e.g. mononucleosis, tuberculosis, hepatitis B |
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Definition
disease that is intermediate between acute and chronic, e.g. subacute sclerosing panencephalitis |
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Definition
disease in which the causative agent remains inactive for a time, but then is reactivated to produce symptoms of a disease, e.g. shingles |
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Definition
the presence of immunity in most of a population The rate at which a disease spreads and the number of people affected are determined in part by the herd immunity. Vaccination can provide immunity to specific diseases. People who are immune to an infectious disease will not be carriers. They act as barriers to the spread of the disease |
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Definition
– the invading microbes are limited to a small area of the body, eg. abscess |
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– microbes and their products are spread throughout the body by the blood or lymph. e.g. measles |
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Definition
agents of a local infection enter the blood or lymphatic system and spread to other areas of the body. e.g. gingivitis and tooth abscesses may result in infections of the heart valves or kidney. |
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Definition
an acute infection that causes the initial illness |
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Definition
is a disease caused by an opportunistic pathogen after the primary infection has weakened the body’s defenses, e.g. Pneumocystis pneumonia in AIDS patients |
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Definition
an infection that does not cause any noticeable illness. e.g. polio, hepatitis A in certain individuals |
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Definition
factor or factors that make the body more susceptible to disease, e.g. gender, climate, age, fatigue, diabetes, malnutrition |
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Definition
time between the intial infection and the onset of clinical signs/symptom |
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early mild symptoms such as aches and malaise |
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Definition
- clinical signs and symptoms are evident, an immune response is mounted, the patient will either overcome the pathogen or the patient dies |
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Definition
signs and symptoms of the disease subside; patient is vulnerable to secondary infections. |
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– person regains strength and returns to prediseased state. Recovery has occurred |
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Definition
continual source of the disease organism; it may be human, animal or non living |
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Definition
people who harbor pathogens and transmit them to others without exhibiting any signs of the disease |
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Definition
any disease that is transmissible from animals to man |
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Definition
exist for many zoonoses, e.g. skunks and bats harbor the Rabies virus see Table 14.2 on pg. 432 |
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Definition
– two major nonliving reservoirs are soil and water e.g. soil harbors fungi that cause ringworm; Clostridium botulinum the bacterium that causes botulism and Clostridium tetani, the bacterium that causes tetanus. Contaminated water is a reservoir for Vibrio cholerae which causes cholera and Salmonella typhi which causes typhoid fever. |
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Three Routes of Transmission |
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Definition
1. Contact. 2. Vehicle. 3. Vectors |
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Definition
Direct, Indirect, Droplet |
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Waterborne, Food borne Airborn |
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involves a nonliving object such as towels, bedding, cups, silverware, toys |
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microbes spread in droplet nuclei (coughing, laughing, sneezing, talking) that travel less than 1 meter from the reservoir to the host. Fig. 14.6 pg. 433 |
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tapeworms, food poisoning, e.g. that caused by Bacillus cereu |
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spread of agents of infection by droplet nuclei in dust that travel more than 1 meter from the reservoir to the host e.g. fungal spores in the transmisison of histoplasmosis |
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Definition
passive transport of the pathogen on a vector’s body part , e.g. a fly comes into contact with feces containing Shigella organisms, then lands on food at a picnic. People ingest the food and become ill with bacillary dysentery |
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Definition
active process that involves replication of the pathogen inside the vector prior to transfer to another host, e.g. rat flea and plague, mosquitoes and heartworms, mosquitoes and malaria |
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Definition
any nonliving object involved in the spread of an infection |
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animals that carry pathogens from one host to another Table 14.3 |
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What is the 8th leading Cause of Death |
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Definition
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Definition
most nosocomial infections were caused by G+ microbes including Staphylococcus aureus |
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Definition
gram-negative bacilli, Escherichia coli and Pseudomonas aeruginosa |
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Definition
antibiotic resistant gram-positive bacteria, Staphylococcus aureus and Enterococcus spp |
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Definition
34% of the nosocomial infections are due to Staphylococcus aureus and Enterococcus spp. 32% of the nosocomial infections are due to Escherichia coli and Pseudomonas aeruginosa |
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What are most nosocomial infections? |
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Definition
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20% of Noscomial infecitons |
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Definition
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one whose resistance to infection is impaired by disease, therapy, or burns |
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Term
Emerging Infectious Diseases |
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Definition
diseases that are new or changing, showing an increase in incidence in the recent past, or a potential to increase in the near future. Table 14.6 pg. 439-440 |
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Definition
the science that studies when and where diseases occur and how they are transmitted in populations |
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There are 3 types of investigations that can be used to analyze the occurrence of a disease |
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Definition
descriptive, analytical and experimental. |
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Definition
procedure that requires health care workers to report specified diseases to local, state and national health officials. Table 14-7 pg. 430 e.g. AIDS, measles, polio, gonorrhea, tetanus, typhoid fever, tuberculosis |
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Definition
The Centers for Disease Control and Prevention in Atlanta, GA. This is a branch of the US Public Health Service The source of epidemiological information in the USA |
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Definition
the number of people who have a specific disease |
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Definition
the number of deaths due to a specific disease |
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Definition
the number of people with the disease total population exposed to the disease |
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Term
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Definition
he number of people who died from a disease the number of people who were ill from the disease |
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