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BSCI223 Module 3 Vocab
Microbiology vocabulary focusing on immunology.
20
Microbiology
Undergraduate 2
12/14/2011

Additional Microbiology Flashcards

 


 

Cards

Term

Acellular

Vaccine

Definition
contain only fragments of bacteria that will stimulate a strong immune response
Term

Active

Immunity

Definition
when you actively produce antibodies against an antigen either naturally (getting over an infection) or artifically (vaccine)
Term

 

 

 

Adaptive

Immunity

Definition
resistance against pathogen that acts more effectively upon subsequent infections with the same pathogen; specificty, inducibility, clonality, unresponsiveness to self, memory
Term


ADCC

(antibody-dependent cellular cytotoxicity)

Definition
once antibodies coat the surface of a pathogen, natural killer lymphocytes (NK cells) bind to the Fc region of the antibody and lyse the target cells with perforin and granzyme
Term
Adhesins
Definition
molecules that attach pathogens to their target cells
Term
Adjuvant
Definition
immunological agent that modifies the effect of other agents, such as a drug or vaccine, while having few, if any direct effects when given by itself.
Term
Allergy
Definition
an immediate hypersenstive response against an antigen
Term
Antibody
Definition
(immunoglobulin) proteinaceous antigen-binding molecule secreted by plasma cells
Term
Antigen
Definition
molecule that triggers a specific immune response
Term
Antigen Presentation
Definition
(adaptive immune response) a virus infected antigen presenting cell (dendritic cells, B cells, macrophages) goes towards the lymph nodes where it presents the virus epitope with MHC I protein (major histocompatibility complex).
Term
Antigenic Mimicry
Definition
production of host antigens by a parasite, enabling it to avoid detection by the host's immune system.
Term
Attenuated Virus
Definition
a weakened virus with reduced ability to cause, infect, or produce disease.
Term
Bacteremia
Definition
the presence of bacteria in the blood
Term

B-Cell

(B lymphocyte)

Definition
lymphocyte that arises and matures in the red bone marrow in adultsa and is found primarily in the spleen, lymph nodes; secretes antibodies
Term
CD4+ T-Cells
Definition
T cell with CD4 protein. CD4 receptor binds to the cells with MHCII complexes that have digested some antigen, when bound it activates the cell. One activated, they differentiate into effector (acivate B cell, release cytokines, or memory)
Term
Chemokine
Definition
an immune system cytokine that signals leukocytes to rush to the site of inflammation or infection and activate other leukocytes.
Term
Complement
Definition
part of the innate immunity. complement proteins in blood serum interact with antibodies and other chemical substances to cause the disintegration of foreign cells and enhance other immune functions such as phagocytosis.
Term
Constant Region
Definition
part of the antibody that is the same for all antibodies (makes up the Fc region and hinge)
Term
Cytokine
Definition
proteins secreted by many types of cells that regulate adaptive immune responses (intercellular mediators).
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