Term
What condition is caused by the compression of the superior colliculus due to a tumor of the adjacent pineal gland? |
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Definition
Parinaud Syndrome (paralysis of upward gaze) |
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Term
Name the region of the cortex that controls voluntary eye movements. |
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Definition
Frontal Eye Fields (rostral to primary motor cortex) |
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Term
What syndrome is caused by blockage of PICA? |
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Definition
Wallenberg's Syndrome (dorsal-lateral medullary) |
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Term
List the clinical features that characterize Wallenberg's Syndrome. |
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Definition
IPSIlateral loss of pain and temperature from FACE
CONTRAlateral loss of pain and temperature from BODY |
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Term
Which two cranial nerves, within the auditory meatus, are served by the labyrinthine artery? |
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Definition
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Term
List the cranial nerves and whether they are:
- motor, sensory, and/or parasympathetic
- if sensory, what is the peripheral sensory ganglion
- if parasympathetic, in which ganglion does the postparasympathetic neuron reside? |
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Definition
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Term
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Definition
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Term
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Definition
Anterior Aternating Hemiplegia (Weber's Syndrome)
- ipsilateral opthalmoplegia
- controlateral hemiparesis
if corticobulbar is involved:
- contralateral paralysis of lower face, tongue, and trapezius |
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Term
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Definition
Claude's Syndrome
Red Nucleus = motor control
- ipsilateral opthalmoplegia (CN III)
- contralateral hemiparesis (descending corticospinal tract)
- contralteral paralysis of lower face, tongue, and shoulder (corticobulbar tract)
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Term
Given the orientation of PSNS and somatic motor fibers within CN III, what effects will compression and ischemia have? |
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Definition
Compression: pupillary deficit alone
Ischemia: somatic motor deficits alone |
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Term
Describe the path of CN IV from the trochlear nucleus as it exits the brainstem. |
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Definition
axons travel dorsally---->around periaqueductal gray----------->CROSS---->exit from dorsal surface---->between superior cerebellar and posterior cerebral aa. |
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Term
How is a distal CN IV lesion distibuished from a lesion closer to the trochlear nucleus? |
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Definition
Distal lesion - affects ipsilateral eye
damage to nucleus - affects contralateral eye |
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Term
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Definition
Compensatory response to Nerve IV Palsy - head is tilted to side of normal eye. |
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Term
A patient with nerve IV palsy would have difficulty performing which 2 tasks? |
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Definition
reading and walking down stairs |
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Term
Vascular insufficiency of which arteries could cause sixth nerve palsy? |
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Definition
Basilar
Basilar aa. branches - Circumferential (serving pons) |
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Term
Why is CN VI especially susceptible to compression injuries? |
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Definition
It courses over a bony ridge. |
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Term
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Definition
VI Nerve Palsy
convergent strabismus (affected eye turned in)
compensation: turn hear toward affected side |
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Term
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Definition
Middle Alternating Hemiplegia
- ipsilateral opthalmoplegia (VI n. palsy)
- contralateral hemiplegia (CST)
- dysarthria (tongue) - CBT |
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Term
Describe the events of the near response. |
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Definition
- eyes move in the opposite direction (vergence)
- pupillary constriction
- increased accommodation |
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Term
What controls vergence movements? |
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Definition
Bilateral input from supraoculomotor nucleus to the oculomotor nuclei. |
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Term
What controls horizontal gaze? |
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Definition
Paramedial Pontine Reticular Formation
PPRF |
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Term
What drives the PPRF and what does it project into? |
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Definition
driven by contralateral frontal eye fields
projects to ipsilateral abducens nucleus
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Term
Describe how horizontal gaze is achieved once the abducense nucleus receives input from the PPRF |
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Definition
some abducens nn--->innervate lateral rectus mm
remaining abducens nn--->cross midline--->ascend as medial longitudinal fasciculus--->contralateral occulomotor nucleus--->medial rectus of that eye
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Term
Describe the voluntary neural control of vertical gaze |
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Definition
bilateral inpur from FEF--->to riMLF--->occulomotor and trochlear nuclei |
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Term
What causes parinaud syndrome (paralysis of upward gaze)? |
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Definition
compression of the superior colliculus |
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Term
Describe thevestibulo-ocular reflex pathway. |
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Definition
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Term
What are the effects of a lesion in the left vestiular nerve or nuclei? |
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Definition
- right vestibular nuclei becomes dominant
- eyes drift to the left but snap back to right = right-beating nystagmus
- left-staggering gait |
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Term
Describe the effects of lesion #1.
[image] |
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Definition
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Term
Describe the effects of lesion #2.
[image] |
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Definition
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Term
Describe the effects of lesion #3.
[image] |
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Definition
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Term
Describe the effects of lesion #4.
[image] |
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Definition
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Term
What is the following lesion known as? What are its effects?
[image] |
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Definition
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Term
What test is used to test the integrity of the vestibular pathways? Describe the results of the test. |
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Definition
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Term
Describe the syndrome characterized by the following:
- Ptosis
- Pupillary constriction (miosis)
- Anhidrosis (lack of sweating) on the face |
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Definition
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Term
How is minor/early compression of CN III distinguished from a vascular insult? |
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Definition
compression - affects peripherally located parasymp. fibers---->pupillary deficit
vascular insult - somatic nerve fibers located more centrally----->eye movement deficit |
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Term
Which different types of sensory information is relatyed to the sensory cortex via the VPL nucleus and the VPM nucleus? |
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Definition
VPL - sesnsory info from body
VPM - discriminatory touch, conscious propioception, vibration from face and oral cavity |
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Term
Describe the pathway that conveys the following information from the head.
- pain/temperature
- touch/pressure |
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Definition
pain/temperature: primary neurons in trigeminal ganglion--->secondary neurons in chief sensory nucleus of V--->VTT (crosses midline) or DTT--->VPM--->primary sensory cortex
touch/pressure: primary neurons in trigeminal ganglion--->turn caudally within brainstem to form spinal tract of V---> VTTcrosses midline--->VPM--->primary sensory cortex |
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Term
Which CN's receive sensation from the ant. 1/3 of the tongue and the post. 1/3 of the tongue? |
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Definition
ant. 1/3 = CN V
post. 1/3 = CN IX |
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Term
Which 4 CN's project to the spinal nucleus of V--->VTT (crosses over)--->VPM--->sensory cortex? |
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Definition
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Term
Which three CN's receive stimuli for the corneal (blink) reflex? |
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Definition
CN II - bright lights
CN VIII - loud noise
CN V - direct corneal contact |
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Term
Which CN stimulates the closure of the eyes during the corneal reflex and what is the result of a lesion in the efferent arm of this nerve? |
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Definition
CN VII
lesion: loss of reflex from ipsilateral eye |
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Term
What is trigeminal neuralgia? |
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Definition
Pain of unknown origin associated with V2 or V3 mostly.
Treatment: cut pain and temperature fibers within spinal tract of V. |
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Term
Which 3 CN's convey taste and from where? |
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Definition
CN VII - Ant. 2/3 of tongue
CN IX - Post. 1/3 of tongue
CN X - Epiglottis |
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Term
What is the effect of a lesion in the rostral nucleus solitarius or tract? |
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Definition
ipsilateral loss of taste
cause message is carried through uncrossed solitariothalamic tract to VPM |
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Term
A lesion to which nucleus results in the loss of the gag reflex? |
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Definition
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Term
What lesion is indicated by the deviation of the uvula to the normal side? |
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Definition
lesion in nucleus ambiguus (loss of motor innervation to levator veli palatini) |
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Term
What lesion results in deviation of the uvula to the affected side? |
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Definition
lesion in UMN corticobulbar input; cause - crossed pathway. |
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Term
What is the effect of bilateral damage to the nucleus ambiguus and why? |
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Definition
complete laryngeal paralysis
death
loss of gag reflex |
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Term
Describe the gag reflex pathway. |
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Definition
sensory info to spinal nucleus of V--->bilateral projection to nucleus ambiguus--->efferent limb of reflex |
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Term
State whether the following muscules have a primarily contralateral or ipsilateral UMN drive.
- Trapezius
- SCM |
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Definition
Trapezius - contralateral
SCM - ipsilateral
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Term
A lesion in the right CN XI will cause the head to turn to which side? Which shoulder will be affected? |
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Definition
right side - cause lesion causes paralysis of right SCM, which normally rotates head to the left.
right shoulder sags - cause lesion causes paralysis of right trapezius |
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Term
UMN lesions will cause weakness in which SCM and trapezius muscle? |
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Definition
ipsilateral SCM
contralateral trapezius |
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Term
A unilateral lesion of the hypogloassal nucleus or tract will cause deviation of the tongue to which side? |
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Definition
to the affected side (cause of paralysis and atrophy of musculature ipsilateral to side of lesion) |
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Term
An UMN lesion will result in deviation of the tongue to which side of the lesion? |
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Definition
contralateral side of the lesion (cause corticobulbar input to hypoglossal nerve is crossed) |
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Term
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Definition
Inferior Alternating Hemiplegia
ipsilateral paralysis and deviation of tongue
contralateral hemiparesis |
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Term
An UMN lesion will cause deviation of the uvula to which side? |
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Definition
ipsilateral side of lesion
(cause of palatal weakness on contralateral side of lesion, allowing muscles in ipsilateral side to dominate)
[image] |
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Term
Which vessels supply blood to the following regions
- inner retina
- outer retina |
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Definition
inner: central retinal aa and vv
outer: long and short posterior cilliary aa |
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Term
What is the pathway of flow of aqueous humor? |
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Definition
enters posterior chamber from cilliary process vasculature--->through pupil into anterior chamber--->through trabecular meshwork into vv |
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Term
What is high intracoluar pressure known as? |
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Definition
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Term
Name the 3 cell types of the direct pathway and the 2 cell types of the indirect pathway. |
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Definition
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Term
Why are rods more sensitive, with less spatial resolution than cones? |
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Definition
rods: high convergence---->single photon has better chance of activating retinal ganglion cell
[image] |
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Term
Which PhR cell responds to the following light ranges?
- scotopic-mesopic
- mesopic-photopic |
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Definition
rods and cones (respectively) |
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Term
Describe the dark current and what changes occur within the cell under in light. |
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Definition
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Term
What type of cone bipolar cell is described below?
"responds to an increase in illumination vs. background |
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Definition
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Term
What type of cone bipolar cell is described below?
"responds to a decrease in illumination vs. background" |
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Definition
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Term
Describe the events of phototransduction in the rod system when exposed to light |
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Definition
rod hyperpolarization--->rod bipolar depolarization--->amacrine cell depolarization--->ganglion on cell depolarized, off cell hyperpolarized |
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Term
Describe the events of phototransduction in the cone system when exposed to light |
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Definition
cone hyperpolarized--->on bipolar cells depolarized, off bipolar cells hyperpolarized--->on galnglion depolarized, off ganglion cell hyperpolarized |
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Term
What information are amacrine cells involved in the analysis of? |
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Definition
detection of movement and directionality of movement |
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Term
Distinguish between linear and non-linear spatial responses of ganglion cells. |
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Definition
linear: ganglion cell responds to specific phase (light or dark) of light
non-linear: ganglion cell responds to change in phase (light to dark or vice versa) |
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Term
List the 3 types of RGCs and their
- location in the retina
- spatial resolution
- function |
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Definition
Midget (80%) (P-cells)
fovea mostly; high spatial res.; detail analysis
red-green
Parasol (10%) (M-cells)
least in fovea; low spatial res.; detection of motion
achromatic
Small Bistratified
uniform distribution; unknown spatial res.
yellow-purple |
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Term
To which cell layers do the large, parasol and midget RGCs project to within the LGN? |
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Definition
magnocellular (M-cell) and parvocellular (P-cell) layers respectively |
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Term
Describe the dorsal-ventral location of the following fibers within the optic radiations.
- superior visual field (inferior retina)
- inferior visual field (superior retina) |
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Definition
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