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MC primary brain tumor, also the worst prognosis |
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Definition
GBM - vs Pilocytic which is benign |
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GBM - spreads along white matter tracts |
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GBM & Pilocytic - Glial fibrillary acidic protein: expressed in Astrocytes & other cells |
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Pseudopalasading tumor cells sorrounding central necrosis & hemorrhage |
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Definition
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Occurs in convexities & parasaggital |
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Arises from Arachnoid cells external to brain |
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Meningioma - Spindle cells whorling concentrically with laminated Calcifications |
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Tumor associated with what is considered a peripheral nerve |
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Definition
Schwannoma - CN8 (and all CNs) are considered peripheral nerves due to being covered with schwann cells. |
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Definition
Schwannoma - usually ass with CN8 |
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Definition
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Found in Neurofibromatosis type 2 |
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The only Infratentorial in Adults |
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Definition
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Definition
Oligodendroglioma - have perinuclear halos (clearings). Cells can calcify |
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Definition
Oligodendroglioma - Delicate vasculature |
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Has endocrine symptoms & Bitemporal hemianopia. From Rathke's pouch |
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Definition
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Definition
GBM, Meningio, Schwann, Oligo, Pit - "Grown Men Ordering Some Pussy" |
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Definition
Pilocytic - Benign, vs GBM which is bad |
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Term
2 Kid's tumors that are Cystic with some solid nodules |
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Definition
Pilocytic & Craniopharyngioma |
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Term
Kids tumor well circumscribed and thus can be excised |
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Definition
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Term
The 2 kids tumors that can be Supratentorial |
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Definition
1) Pilocytic - usually Post. fossa but can be in Lobes (near GBM) 2) Cranio - Rathke's |
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Definition
Pilocytic - Eosinophilic elongated cork screw fibers made of Intermediate filaments |
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Kids tumor that involves Neurons |
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Definition
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Kids tumor that's primitive neuroectodermal (PNET) |
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Definition
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The 2 that Compresses 4th ventricle = Hydrocephalus |
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Definition
Medulloblastoma & Ependymoma |
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Definition
Medulloblastoma - Tumor cells sorrounding a lumen (not to be confused with Pseudorossette which sorrounds fibril material) |
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Pseudorossette (Homer-wright) |
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Definition
Medulloblastoma - Tumor cells sorrounding fibrils (not to be confused with True Rossetes which sorrounds a true lumen) |
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Perivascular Pseudorossette |
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Definition
Ependymoma - Tumor cells line the blood vessel |
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Definition
Medulloblastoma - these small blue cells stain blue cuz of prominent nucleus & scant cytoplasm |
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Kids tumor that's radio-sensitive |
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Definition
Ependymoma - Blepharoplasts are Ciliary bodies (Centrioles of microtubules), found near Nucleus. |
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Definition
Hemangioblastoma, RCC, Renal cysts, Retinal angioma. Polycythemia |
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Definition
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Definition
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Pilocytic & Craniopharyngioma |
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Term
Often misdiagnosed as Pituitary adenoma |
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Definition
Craniopharyngioma - is derived from Rathke's pouch remnants = Hemianopia |
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Term
Can calcify with Tooth(enamel) like material |
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Definition
Craniopharyngioma - within Rathke's pouch |
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Term
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Definition
Pilocytic, Medulloblastoma, Ependymoma, Hemangioblatoma, Craniopharyngioma - "Pediatric males eat hot chicken" |
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Term
Name the 3 that are associated with Calcifications: |
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Definition
DDx based on location: 1) Meningioma - psomomma body 2) Oligodro - Fried egg cells 3) Cranio - Tooth like in Rathke's |
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Term
Name 3 characteristics to distinguish between Metastasized vs Primary brain tumors: |
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Definition
1) Met = Multicentric. Primary = singular. 2) Met are always well circumscribed. 3) Met occurs @ gray/white junction. |
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