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Brain and Pathology
University of Kansas, Professor Doug Denney
123
Psychology
Undergraduate 4
03/06/2010

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Cards

Term
neocortex
if a reptile or bird doesnt have this.. they just use ___ for motor stuff
is it new?
what is it?
how many layers? tell me about it.
are the layers all the same thickness?
Definition
if they dont have it - the corpus striatem does movement.
most evolved of all! has most layers. like hippocampus is pretty evolved -it has 4 layers
its a 2-3mm mantel covering the cerebral hemispheres
6 layers- columnar. surface = I. closest to brain = VI
not all same. III&V are ouput and IV is input - see BA
Term
central fissure
Definition
divides frontal and parietal
Term
longitudinal fissure
Definition
deepest, L to R
Term
lateral fissure
Definition
2nd deepest- boxing glove thumb
Term
parietal occipital fissure
Definition
bw p and o, duh.
Term
4 lobes. name and location
Definition
frontal
parietal
occipital
temporal
PICTURE
Term
temporal lobe
Definition
thumb OF boxing glove
Term
frontal lobe
Definition
?
Term
prefrontal cortex
Definition
projection zone of thalamus. very front of brain
Term
post central gyrus
Definition
BA 123 in parietal. right behind fissure
hemineglect, if it affects the non-dominant hemisphere.
sensory homonculus
Term
pre central gyrus aka primart motor cortex
Definition
in frontal, in front of fissure
motor homunculus
Term
primary motor projection area
Definition
definition
Term
premotor area
Definition
definition
Term
somatosensory projection area
Definition
in parietal
Term
primary auditory projection area
Definition
definition
Term
primary visual projection area
Definition
definition
Term
broca's area
Definition
definition
Term
wernike's area
Definition
receptive aphasia . carl. localized in back of left temporal
Term
association area
Definition
definition
Term
motor homunculus
shown on... gyrus
Definition
somatotopic representation (organization of correspondence w places in body and brain) of primary motor projection area.
on precentral gyrus
PICTURE p 72
Term
somatosensory homunculus
shown on --- gyrus
Definition
somatotopic representation of primary projection area.
on postcentral gyrus
PICTURE p 72
Term
brodmann areas
Definition
Brodman took core samples of the brain and saw that come places the layers were diff thicknesses p73 - more info!
Term
executive functions
Definition
happen in frontal lobe0 integrate stuff into a plan
Term
aphasia
Definition
definition
Term
agnosia
Definition
definition
Term
propopagnosia
Definition
definition
Term
apraxia
Definition
definition
Term
hemispheric specialization
Definition
definition
Term
split brain patients
Definition
definition
Term
limbic system
Definition

[image]

[image]

Term
Telencephalon
parts -
Definition
corpus striatem and rhiencephalon are here.
Term
corpus striatem aka basal ganglia
deals with -
diseases related?
location
Definition
deals with motor/procedural memory
and extrapyramidal and 'getting ready to move'

huntingtons/parkinsons
page 66 location
Term
motor/procedural memory
where
examples
does clive have this?
parts?
Definition
in corpus striatem
music/riding bike
yes.
parts - lenticular and caudate nucleus
Term
lenticular nucleus
part of the ___
parts - __ and ___
Definition
part of the corpus striatem
parts include putamen(lateral) and globus pallidus (medial)
Term
putamen (lateral surface of lent.nucleus)
Definition
definition
Term
globus pallidus()medial surface of lent nuc
Definition
definition
Term
caudate nucleus
part of the ___
ends in the ___
Definition
part of the corpus striatem
ends in the amygdala
Term
episodic/declaritive memory
happens where?
can clive?
Definition
happens in hippocampus.
clive cant.
lists, wsj article to recall later, card catalog of where the books are all stored.
Term
Clive weiring
talk about this case.
mention - part of the brain with damage.
what type of memory he can (and where that is) and cant do.
what he likes
where his emotional issues come from.

clue: his 'thumb' is damaged
Definition
video. hippocampal damage due to sickness. he has episodic memory issues. he thought every minute was the first he had been fully awake. the memory of music was intact. had emo intensity bc of frontal lobe
his motor or procedural memory is still intact bc it happens in corpus striatem. think huntingtons etc. he can still learn music even if he doesnt ever remember seeing the music - he gets better if he practices.

his 'thumb' is damaged
Term
rhiencephalon
parts

function
Definition
smell brain
parts: olfactory tracts, amygdala, mamillary bodies, septum, hippocampus and hippocampal formation and hippocampus commisure, cingulate gyrus(is above, follows curve or corpus collasum on medial side of each hemisphere of cerebrum).
all of these structures are complexly interelated in such matters as motivation, emotion, learning, and memory.
Term
amygdala
where?
works w/
Definition
end of caudate nucleus
emotional memory
Term
emotional memory
where?
what
Definition
happens in the amygdala.
causes anxiety. helpful. learns about things in environment that cause emotional harm and tries to avoid.
Term
hippocampus
buried where?
describe the hippocampal formation.
works w/ what kind of memory.
comparative to a ____ ___ in a library
Definition
thumb IN boxing glove
in temporal lobe

the HF starts w/ the fornix w/ two arms that move laterally as they encircle the thalamus and end in the hippocampus. the two arms of Fornix are joined by the hippocampal commisure

seems to be a consolidator and organizer of memory. declaritive
Term
amnesia
Definition
definition
Term
retrograde amnesia
Definition
definition
Term
antegrade amnesia
Definition
definition
Term
procedural memory in Cs
Definition
definition
Term
Diencephalon
part of the ____
inside is the ___, ____ and ___
Definition
part of the forebrain.
inside is the thalamus, hypothalamus, and pituitary gland
Term
thalamus
where
f(x)- the great ____
shape
Definition
is located above the tectum/ceiling of the midbrain. forms 'roof' and upper sides of 3rd ventricle- p 53
Principle relay point for sensory and motor information into cerebrum- blind sight flower/hammer
the great switchboard. coms- all incoming, cept smell goes to thalamus
shaped like 2 footballs - joined by massa intermedia
has important thalamic nuclei!
Term
ventrobasal complex is a ____ in the ____ , function?
recieves from _ and sends from _
Definition
thalamic nuclei in the thalamus , somatosensory
location - pg 53/4
recieves from lemniscal system and neospinothalamic tract and sends to primary somatosensory projection area BA 1, 2, 3. post central gyrus , parietal lobe
Term
lateral genticulate nucleus
function
receives from
sends to
Definition
thalamic nuclei in the thalamus , vision
location - pg 53/4
receives from optic tract and superior coluculli (BA 17) - occipital lobe
Term
medial genticulate nucleus
location on pic?
function
receives info from inferior colliculli and sends to primary auditory projection areas - ba 41&2 in temporal lobe
Definition
thalamic nuclei in the thalamus , hearing
location - pg 53/4
Term
hypothalymus
beetsham
Definition
B-ehavior E-ndocrine
E-motion T-emperature control
S-leep/wake cycles H-ungar/Thirst
A-utonomic Control M-emory
Is the Endocrine Control Center
Secretes Regulatory Hormones
Controls ANS stimulation of Adrenal Medulla
Term
autonomic motor system - command center is where?
Definition
command center of this is in the hypothalamus
Term
study hard, babe. study hard.
Definition
encouragment.
Term
posterior pituitary / neurohypophesis
signals come from?
Definition
the pituitary that is controlled by signals from the hypothalamico-neurohypophesial pathway which descends the indinibulum... which is all controlled by the hypothalamus

page 56-60- go OVER!
Term
infinibulum
Definition
things descend there.
Term
endocrine glands
Definition
definition
Term
anterior pituitary / adenohypophesis
Definition
controlled by CHEMICALS releasing factors and inhibit of release factors. released from tubero-infidibular pathway

example - prolonged stress - CRF- corticotrophic release factor comes from hypothalamus to anterior pituitary down the t-i path. and makes it make ACTH and cotisol stuff
p 56-58, 61-63- GO OVER!!
Term
tuber-infidibular pathway
Definition
goes to anterior pituitary
Term
portal vessel system
Definition
if it comes fown the T-I path it goes into here.
it's a vasciluar system that then descents infindibulum
Term
example of posterior pituitary process
___ stimulates __. releases __ results in ___
Definition
hypothalamus stimulates posterior pituitary to release oxycotin. uterus contracts. result= birth
and then nursing happens too.
initial product is collostrum, not mothers milk until has oxycotin to release other stuff - page 60
Term
hypothalamico-neurohypophesial pathway
Definition
definition
Term
mesencephalon/midbrain
where?
how is it like a MIDDLE income family's HOUSE
Definition
under pons
it has a ceiling (tectum) and floor (tegmentum)
Term
tectum
house?
parts
f(x)?
Definition
on p 49
ceiling
colliculi
superior and inferior
Term
tegmentum
house?
f(x)?
Definition
floor.

red nucleus and substantia nigra
grace. extrapyramidal
Term
quadrageminal bodies
Definition
4 colliculiiii
Term
superior colliculi
where?
f(x)?
looks like?
sends info to
Definition
in tectum
protopathic seeing
eye movement and reflexes,
visual orientation
DD's scanning the classroom/lifeguard's are superior
defensive 'oh god it's going to hit me' reflex
hindbrain boobs
along with optic tract - sends info to lateral genticulate body in thalamus ( its BA 17 in occipital)
Term
inferior colliculi
where?
f(x)?
looks like
sends info to
Definition
in tectum
protopathic hearing
some sound localization and 'startle response'
hindbrain big boobs
sends info to medial genticulate body in thalamus
Term
anterior commisure
Definition
definition
Term
cerebellum
what kind of pyramidal? reg or extra?
function?
lots or less neurons than brain?
Definition
pretty. brain's metronome.
extrapyramidal - good puppet/grace /coordination of all experiences
receives LOTS of proprioceptice data
70 billion neurons - more than brain.
more 'frames per second'

covers the 4th ventricle as seen on p 49
Term
pons
Definition
definition
Term
mylencephalon of hindbrain - rhomencephalon
Definition
definition
Term
medulla is in the ___ of the ____
function
Definition
____ is in the mylen of the hind.
basically the swollen spinal cord but thicker and has 1/2 of cranial nerves attached (6-12) and vital nuclei
and it keeps you all alive and stuff
Term
vital nuclei
Definition
are in medulla and are part of cranial nerves
Term
meninges - dura, archnoid and pia
Definition
definition
Term
word
Definition
defn
Term
What is the lateral ventricle

what is the third ventricle

What is the 4th ventricle

or where are they

what happens there

where are they?
Definition
C shaped ventricles in middle of brain - have anterior horn in front. posterior horn in back and in the mid of the 2 is the 3rd ventricle like a cradle bw the 2 lateral ventricles

in middle

in brainstem bw cerebellum and pons

http://www.obfocus.com/images/csf.gif
Term
how are the ventricles connected?
Definition
LATERAL - intraforamen - 3RD VENTRICLE - cerebral aqueduct- 4TH VENTRICLE- foramen of luschka (the foramen of megendie goes thru the medulla to connect the 4th ventricle to the central canal straw of the spinal corn thru the foramen of Lushka!~)
Term
cerebral aqueduct connects what two ventricles
Definition
3rd and 4th
Term
cerebral spinal fluid's function?
made by? where are these?
how much made a day? compared to a bev

does it have another f(x)

how does it move around?
Definition
drains brain waste and gives support
made by specialized cells lining roofs of ventricles - particularly the lateral ventricles - called choroid plexus
1 can of coke - 600-700ml- ventricles are filled w/ the stuff.
now we know it sends some chemical messages

the superior sagittal sinus picks up csf and drains it away . page 45
Term
cranial nerve - optic II
Definition
definition
Term
cranial nerve- optic chiasma
Definition
definition
Term
cranial nerve - olfactory - I
Definition
definition
Term
olfatory bulb
Definition
definition
Term
auditory - vestibular nerve - viii
Definition
goes through infereior colliculi
Term
commisure
Definition
definition
Term
ventricle
Definition
definition
Term
hippocampal commisure
Definition
connects the 2 arms of the fornix of the hippocampal formation.
losing 1 is fine because the other will compensate in a few months.
Term
corpus collosum (commisure
location
Definition
is the largest of the commissural fibers
cut to cure epilepsy
Andrew's friends sister
bottom of longitudanal fissure
page 65 picture
Term
cerebellar commisure
Definition
definition
Term

[image]

Definition
frontal, parietal, occipital, temporal
Term
the _______ separates into the __________ and _________.
the other vessicle , the _______. separates to __ and ___
Definition
the hindbrain separates to the mylencephalon and mesencephalon and the forebrain separates to the telencephalon and diencephalon
Term
right is to left as agnosia is to ___
Definition
Left is to aphasia and language.
right is agnosia and knowing and recognizing
Term
anomia
Definition
can't recog faces
Term
Mother's friend case
Definition
if she had had a stroke on her left, would affect her language.
she had stroke on R - sensory - left side doesnt exist anymore. L sensory neglect - more common than right sensory neglect
Term
Gill Lesalle
Definition
law and engineer degree+stoke bc of frontal lobe aneurysm - how we use the info given by other parts of brain. has abilities but cant use them to apply anything or problem solve.
Term
egaz moniz
Definition
invented, got nobel prize for lobotomy.
Term
embryological development
PMR or FMH
Definition
[image] page 46 neural tube(forerunner of brain and spinal cord) starts forming at day 21 and somites go around it (muscle forerunners) at day 23 page 47
Term
prosencephalon into __ and __
Definition
telen and dien
Term
mesencephalon into _
Definition
midbrain
Term
hindbrain into _ and _
Definition
mylen and meten
Term
the neural plate enfolds, forming ___
then it becomes _ swellings known as ___ ___ ___
Definition
the neural plate enfolds, forming neural tubethen it becomes 3 swellings known as primary brain vessicles
Term
What do these embryonic divisions of the brain become in the adult brain?



tel di mes met my

Can Eggs, Toast and Ham make party crazy men obese?
Definition
Telencephalon - cerebrum - Can
Diencephalon - Epithalmus, Thalmus, Hypothalmus - Eggs, Toast & Ham
Mesencephalon - Midbrain - Make
Metencephalon - Pons, Cerebellum -Party Crazy
Myelencehpalon - Medulla Oblongata - Men obese?
Term
metencephalon separates to ___ and ___
Definition
pons and cerebellum (separated by 4th ventricle)
Term
CASE: locked in
Definition
pons
Term
pons
Definition
thicker and rotund and carries transverse neurons (a commissure) across hemispheres of cerebellum - r to left
Term
reticular formation
what
where
function
Definition
in midbrain behind pns.
network of neurons w/ short axons and lotsa synapses
page 50
retiulospinal pathway comes from bottom of extrapyramidal signals from cerebellum in the meten

works with being fully alert- sets level of cortical alertness
Term
Where's the lesion?

1. facial weakness ipsilateral to body weakness
2. altered level of consciousness
3. dysarthria (difficulty pronouncing words!) and dysphasia (difficulty swallowing)
4. can't be fully alert
Definition
What happens when you have a lesion here
1. in high pons or above
2.in brain stem or dysfunction of both cerebral hemispheres
3. brainstem or cerebellum
4. reticular formation
Term
pineal nerve was though to be center of ____ because it wasn't neurological tissue and didn't have a twin. singular.
location?
Definition
thought to be center of soul by descartes
it calcifies w/ age
located on top of superior coliculus - between pair of thalamuseses .
Term
hypothalamus from class
function
Definition
lesser thalamus - floor of 2rd ventricle
basic drives (sex food etc)
command center of autonomic.
neuroendocrine system- influences pituitary
Term
important thalamic nuclei
1. lateral genticulate body
2. medial genticulate body
3. ventrobasal complex
functions?
Definition
1 vision
2hearing
3somatosensory
Term
where is the command center for neuroendocrine system that coms with the pituitary?
how does it do that?????
Definition
in the hypothalamus
Term
pituitary
parts
sends out
controlled by
Definition
has the posterior and anterior pituitary and sends out hormones and controlled by hypothalamus.
Term
switchboard of thalamus is represented on p 54.
Definition
Term
limbic system includes 8 parts
PICTURES
Definition
1.cingulate gyrus kinda in a circle around everything.
2. Thalamus - in the middle
3. fornix- encircles thalamus and ends in mamillary body
4. hypothalamus - under thalamus
5. mamillary body
6. hippocampus -
7. amygdala
8. olfactory bulbs.
page 67,8
Term
fissure
Definition
big dent
Term
sulci
Definition
lil dent
Term
gyrus
Definition
folds
Term
4 main fissures. name them
Definition
central, longitudinal, lateral, parietal-occipital
Term
Left:
LAAAS
Definition
Language, sequential, analytic, aphasia, anomia.
Term
Right:
which osia?
Definition
spatial (integration), holistic, synthetic, agnosia.
Term
CASE: the gift of speech
what happened.
what does she have and what does that mean - wrong place, wrong time, wrong location.
what were the place, time, and location
Definition
Marilou, 6 yr old girl
normal speech and intelligent to no speech receptive or expressive.
had seizures
Laundau-klefner-
the place was in her speech cortex. the thing was epilepsy and the time was when she was in her window of opps for speech
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