Term
| What happens to a normal aging brain? |
|
Definition
decrease in brain weight
decrease in the number of neurons in the cerebellum
increase in number of plaques
mild memory problems
NO SENILITY AND DEMENTIA |
|
|
Term
|
Definition
| DNA breaks down over time and causes abnormal proteins to be coded for and some proteins are not made at all. leads to loss of neurons and myelination. |
|
|
Term
|
Definition
most common cause of dementia
specific loss of ACh neurons in the nucleus basalis, these neurons usually provide dense ACh input to the hippocampus and cortex; important for normal functioning in those regions (regulate arousal, alertness, memory) |
|
|
Term
|
Definition
loss of memory, spatial disorentation, personality change
eventually other brain areas will be affected
eventually fatal |
|
|
Term
|
Definition
blocks ACh-esterase which leads to a build up of ACh
very expensive
eventually stops working |
|
|
Term
|
Definition
|
|
