Term
Describe the general properties of the bacteria associated with the genus Borrelia, including the physiology and structure of the organism.
Describe the basic features of the pathogenesis and immunity associated with Lyme disease and relapsing fever.
Describe the basic aspects of the epidemiology and clinical manifestations associated with Lyme disease and relapsing fever.
Compare the modes of transmission of the Lyme disease and relapsing fever.
Describe the diagnosis, treatment and control of Lyme disease and relapsing fever.
Describe the approach to diagnosis and treatment and control of relapsing fever and Lyme disease. |
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Definition
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Term
| Where and when was Lyme disease discovered? |
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Definition
| 1977 in Lyme, CT. Caused by Borrelia burgdorferi (named after the guy who found it) |
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Term
| what does Borrelia recurrentis cause? |
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Definition
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Term
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Definition
| gram neg. bacilli. cannot be cultured. look like spirochetes |
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Term
| T/F : the genome is linear and present in mulitple copies in B. burgdorferi |
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Definition
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Term
| what is the leading vector-borne disease in the USA? |
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Definition
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Term
| can humans spread Lyme disease? |
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Definition
| no. they are accidental hosts. |
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Term
| what is Ixodes scapularis? |
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Definition
| the tick that transmits Lyme disease. |
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Term
| what are the maintenance hosts of lyme disease? |
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Definition
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Term
| what are the incidental hosts of the lyme disease? |
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Definition
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Term
| how long is the maturation cycle of Ixodes scapularis? |
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Definition
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Term
| is the bacteria transmitted to the larvae of the infected tick? |
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Definition
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Term
| how are new ticks infected? |
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Definition
| they bite an infected rodent/deer. |
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Term
| when do these ticks lay their eggs? |
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Definition
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Term
| what animal do the ticks mate on? |
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Definition
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Term
| how many stages are present in clinical manifestations of Lyme Disease? |
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Definition
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Term
| what is erythema migrans? |
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Definition
| diagnostic "bulls-eye" rash of Lyme Disease |
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Term
| what are other symptoms in the 1st stage of lyme disease aside from the erythema migrans? |
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Definition
| Influenza-like: malaise, chills, fever, headache, joint and muscle pains. |
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Term
| what two systems are involved in the second stage of lyme disease? |
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Definition
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Term
| what symptoms are seen in the third stage of lyme disease? |
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Definition
| about 6months after skin rash, you see joint pain, swelling and tenderness. |
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Term
| why is it difficult to detect bacteria in blood and tissues after a few weeks (following an intense immune response)? |
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Definition
| bacteria have the ability to switch antigens. The immune response is probably responsible for the symptoms of the second and third stages. |
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Term
| how long do the ticks need to feed to transmit an infective dose? |
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Definition
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Term
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Definition
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Term
| differences between epidemic and endemic relapsing fever? |
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Definition
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Term
| how many relapses with epidemic form? with the endemic form? |
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Definition
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Term
| where can i find a good summary of Rickettsia and Borrelia? |
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Definition
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Term
| if its an epidemic, is it louse or tick borne? |
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Definition
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Term
| if its an endemic, is it louse or tick borne? |
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Definition
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