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Borek Physiology Ch3&5 Lec7
"
15
Anatomy
Undergraduate 1
01/31/2012

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Cards

Term
3 things that happen to pre-mRNA molecule inside the nucleus before it can leave as mRNA
Definition
1. introns are excised
2. 7Methyl-G cap is added
3. Poly-A tail is added
Term
Subphases of Interphase
Definition

G1, S, and G2

("M" phase is simply mitosis, and is therefore not involved in Interphase)

Term
phases of Mitosis and major event thereof
Definition
Prophase: condensation of DNA into chromosomes
Metaphase: chromosomes are lined up on metaphase plate by microtubules
Anaphase: chromosomes are pulled apart to either pole of the now-elongated cell
Telophase: nuclear membrane is reconstructed
(PMAT)
Term
cytokinesis
Definition
division of cytoplasm and constituent organelles. Timing depends on cell type.
Term
Direction NEW DNA strands are BUILT
Definition
5' --> 3'. Nucleotides can ONLY be added to the 3' side of pre-existing nucleotides.
Term
Direction SENSE STRAND of DNA is READ by DNA polymerase
Definition
3' --> 5'. Polymerase runs along template in this direction only. Cause for the need of Okazaki fragments.
Term
A woman has a recessive mutant gene on one X chromosome: (X')(X) and a man has the same mutation on his X: (X')(Y). Do either or both of them display the phenotype of the mutation? If so, which?
Definition
the man
Term
4 cell types of epidermis
Definition
Melanocytes, Langerhans cells, Keratinocytes, Merkel cells
(MeLKeM)
Term
Keratinocytes
(function and location)
Definition
produce keratin (protection)
stratum spinosum (dominant)
Term
Melanocytes
(function and location)
Definition
produce pigment melanin (absorbs UV)
stratum spinosum, adjacent to stratum basale
Term
Langerhans cells
(function and location)
Definition
participate in immune response (derived from bone marrow)
stratum spinosum (sparse)
Term
Merkel cells
(function and location)
Definition
contacts tactile disc (touch sensation)
stratum basale
Term
layers of epidermis from most superficial to deepest
Definition
corneum
(lucidum)
granulosum
spinosum
basale
Term
Three major functions of the skin
Definition
1.Vitamin D production
2.Excretion
3.Protection
(PED)
Term
ABCD's of Skin cancer
Definition
Asymmetry
Borders (irregular)
Color (off)
Diameter (large)
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