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A condition caused by excess secretion of growth hormone after puberty. Skeletal abnormalities develop, affecting the cartilages and various small bones. |
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A toughened layer of connective tissue that encircles and stabilizes a bone at a fracture site. |
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A crack or break in a bone. |
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A large blood clot that closes off the injured vessels around a fracture and leaves a fibrous meshwork in the damaged area of bone; the first step in fracture repair. |
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A condition resulting from an overproduction of growth hormone before puberty. |
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A bridgework of bone trabeculae that unites the broken ends of a bone on the narrow side of a fracture. |
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An inherited condition linked to defective production of fibrillin, a connective tissue glycoprotein. Extreme height and long, slender limbs are the most obvious physical indications of Marfan syndrome; cardiovascular problems are the most dangerous aspects of the condition. |
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osteoclast-activating factor |
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A compound, released by cancers of the bone marrow, breast, or other tissues, that produces severe osteoporosis. |
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A softening of bone due to a decrease in its mineral content. |
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Inadequate ossification, leading to thinner, weaker bones. |
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A reduction in bone mass to a degree that compromises normal function. |
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A disorder caused by inadequate production of growth hormone prior to puberty. |
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A childhood disorder that reduces the amount of calcium salts in the skeleton; typically characterized by a bow-legged appearance, because the leg bones bend under the body's weight. |
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A condition involving weak, brittle bones as a result of a vitamin C deficiency. |
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Elevations, projections, depressions, grooves, and tunnels in the bones. |
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The process of converting other tissues to bone. |
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The process of depositing calcium salts within a tissue. |
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endochondral ossification |
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Definition
Begins with a cartilage model that is gradually replaced by bone at the metaphysis. In this way, bone length increases. |
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intramembranous ossification |
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begins when osteoblasts differentiate within connective tissue. The process produces dermal bones. |
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Hormone that regulates calcium ion homeostasis and leads to a decline in the calcium concentration in body fluids. |
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Hormone that helps regulate calcium ion homeostasis and increases the calcium concentration in body fluids. |
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A large blood clot that soon close off the injured vessels and leaves fibrous meshwork in the damaged area. |
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Supply blood to the inner surface of each epiphyseal cartilage, where that cartilage is being replaced by bone. |
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primary ossification center |
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Definition
The site at which bone development begins. |
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Prevents damaging bone-to-bone contact within the joint. |
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