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Body Organization, Chemistry and Cell Structure and Function
Chapters 1, 2 and 3
49
Physiology
Undergraduate 1
12/11/2010

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Term
pH of cytoplasm
Definition
7.0
Term
IPSILATERAL vs CONTRALATERAL
Definition
same side; opposite side
Term
SAGITAL PLANE
Definition
= MEDIAL PLANE
Term
CORONAL PLANE
Definition
= FRONTAL PLANE
Term
TRANSVERSE PLANE
Definition
= HORIZONTAL PLANE
Term
2 cavities that appear first in embryo development
Definition
POSTERIOR/DORSAL - cranial cavity and vetrebral canal
ANTERIOR/VENTRAL - all other cavities with serous membranes; THORACIC (pleura and pericardium), ABDOMINOPELVIC (peritoneum)
Term
3 components of negative feedback
Definition
sensor, control center and effetor
Term
4 elements that make up 90% of body
Definition
C O H N
Term
IONIC BOND
Definition
attraction of oppositely charged ions; steal electrons from each other to make 8 electrons in each outer ring when bonded as one molecule
Term
COVALENT BOND
Definition
atoms share electrons instead of losing or gaining them
Term
POLAR COVALENT BOND
Definition
molecule is polarized because electrons spend more time on on part of molecule, e.g. WATER
Term
HYDROGEN BONDS
Definition
are weak b/t H+ and a negatively charged molecule/atom
Term
Chemical properties of water
Definition
polarization and H bonds makes good solvent for other polar molecules; high specific heat capacity makes for good isulator; flows freely helping transport stuff.
Term
HYDROPHILIC/HYDROPHOBIC MOLECULES
Definition
water loving, will break up in water, are polarized; water hating, will not break up, are non-polar
Term
% water in blood
Definition
92%
Term
Specific heat capacity
Definition
water has high shc, making it a good insulator
Term
ACID/BASE
Definition
Acids dissociate in water releasing H+ ions; bases dissociate either releasing OH- or taking up H+
Term
normal of blood
Definition
pH 7.4
Term
Blood buffers
Definition
take up H+ or OH- ions; most important are carbonic acid and bicarbonate
Term
Nucleic acids (DNA and RNA)
Definition
composed ofnucleotides, which are phosphate + pentose sugar (deoxyribose or ribose) + nitrogeneous base; are 4 kinds: A T C G
RNA usually single stranded, DNA double
Bases always pair T with A and G with C
Term
molecules for greatest energy storage
Definition
LIPIDS
Term
FATTY ACID
Definition
carbon-hydrogen chains ending in COOH+ acidic group
Term
PHOSPHOLIPIDS
Definition
have a phosphate group in place of third fatty acid; polar with hydrophilic head; backbone of cell membranes; forms spontaneous bilayer
Term
STEROIDS
Definition
are lipids but with very different structure; precursor is cholesterol; e.g. steroid hormones like testosterone and estrogen
Term
AMINO ACIDS
Definition
are 20, 9 essential; differ only at the "R group" part of molecule; are polar and bonded by weak peptide/hydrogen bond; b/c of this, when form peptides, will bend and fold a lot
Term
METABOLISM
Definition
the sum of all chemical reactions in a cell
Term
ATP
Definition
is a high-energy nucleotide
primary energy source
acquired by breakdown of glucose, etc
Term
NUCLEOLUS
Definition
inside nucleus where ribosomes are formed, contains concentration of chromatin and RNA
Term
RIBOSOMES
Definition
protein production
either free in cytoplasm that produced proteins for within cell; or on the ER producing proteins for excretion
Term
ENDOMEMBRANE SYSTEM
Definition
nuclear envelope, ER, Golgi, lysosome, vesicles; all work together to form and secrete proteins
Term
ENDOPLASMIC RETICULUM
Definition
forms vesicles of protein and lopids to transport to other parts of the cell; is rough (proteins) and smooth (proteins and phospholipids)
Term
GOLGI APPARATUS
Definition
receives vesicles from ER (proteins and lipids) and modifies them with enzymes, forms more vesicles wither for in the cell or for secretion; some vesicles formed are lysosomes
Term
PEROXISOMES
Definition
like lysosomes but destroy toxins, liver and kidney have many; also break down fatty acids
Term
VACUOLES
Definition
isolate/encapsulate junk for later lyses
Term
CRISTAE
Definition
inner folded membrane of mitochondria; where proteins that convert ADP to ATP line up for energy
Term
CYTOSKELETON
Definition
anchors the organelles, involved in mitosis
Term
MICROTUBULES
Definition
are tracks for organelle movement esp during cell division
Term
CENTRIOLOES
Definition
in the centrosome (whatever that is) helps from spindle; a single one is anchor for cilium and flagellum; located in the cytoploasm
Term
FACILITATED DIFFUSION
Definition
facilitated uses protein carrier to moves from high to low concentration,but no ATP needed as with active transport
Term
Types of passive movement across cell membranes
Definition
simples diffusion, opsmosis, filtration, facilitated diffusion
Term
Types of active transport
Definition
Active using protein pumps to move molecules across membranes; ENDOCYTOSIS (into cell; phago and pinocytosis); EXOCYTOSIS (of hormones, etc)
Term
HYPERTONIC/HYPOTONIC SOLUTIONS
Definition
Hypertonic solution has high osmotic pressure, pulling in water; Hypotonic solution loses water becuase solute is low. These are relavant to eachother
Term
CRENATION
Definition
shrinkage of RBCS, e,g, surrounding fluid is hypertonic, pulling water from cell
Term
ISOTONIC
Definition
water doesn't move across membranes by osmosis because tonicities are the same; water is NOT isotonic to cells b/c has no electrolytes (can be toxic if no solutes)
Term
Water toxicity
Definition
from too much water, diluting extracellular fluids which forces water into cells, lysing them; to cure, need more salt to give water solute
Term
Cell Cycle
Definition
1. Interphase -- cell getting ready to divide, 3 parts - G1 (growth, organells double, still regular functions), S (synthesis or replaction of DNA) and G2 (transcription and translation of proteins for division).
2. Mitotic stage - M stage - 2 parts: mitosis and cytokinesis; MITOSIS has 4 parts (prophase, metaphase, anaphase and telophase); CYTOKINESIS is the actual division
Term
9 abdominal divisions
Definition
R/L Hypochondriac
R/L Lumbar
R/L Iliac
Epigastric, umbilical and hypogastric
Term
3 types of lipids
Definition
Fats and oils; Phoshpholipids; Steroids
In general, fats don't dissolve in water b/c not polar (except phospholipids have a polar end)
Term
Some Parts of a cell
Definition
NUCLEOLUS in the nucleus, contains most chromatin (disorganized DNA) and RNA; forms ribosomes
RIBOSOMES form proteins
ENDOPLASMIC RETICULUM -- rough has ribosomes to make proteins for export, smooth without ribosome makes lipids/steroids; both transport via vesicles
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