Shared Flashcard Set

Details

Board Review Mania
Goljan 2
25
Medical
Professional
02/25/2008

Additional Medical Flashcards

 


 

Cards

Term
In cancer, how are suppressor genes inactivated?
Definition
point mutations
Term
Transcription of mic from 8 to 14 occurs in what cancer?
Definition
Burkitt's lymphoma. Associated with EBV (increases mitotic rate when it attaches to CD21 and converts B cell to plasma cell).
Term
14:18 translocation occurs in what cancer?
Definition
B cell lymphoma
Term
15:17 translocation occurs in what cancer?
Definition
Acute progranulocytic leukemia (this is the one treated with vitamin A).
Term
Drug predisposing to bladde cancer
Definition
cyclophosphamide (treats Wegener's, RA, minimal change, and others)
Term
Virus predisposing to Kaposi's sarcoma
Definition
Herpes Virus 8
Term
HIV predisposes to what cancer?
Definition
Primary CNS lymphoma
Term
What is the most common cancer associated with radiation?
Definition
Leukemia, particulary CML.
Term
What's the particle associated with basal cell carcinoma?
Definition
UV B light
Term
What substance increases incidence of squamous cell carcinoma?
Definition
Arsenic (also angiocarcinoma of liver). This is bad in Bengladesh.
Term
Retinoblastoma chromosome?
Definition
13
Term
Most common cause of white reflex
Definition
Congenital cataract
Term
What drug predisposes to cataracts?
Definition
corticosteroids.
Term
40% of all cancers include the finding of...
Definition
Thrombocytosis
Term
Most common cause of death in cancer
Definition
gran negative infection
Term
Most common paraneoplastic syndrome
Definition
Hypercalcemia
Term
Explosive onset of pruritic seborrheic keratoses.
Definition
Leser-Trelat sign; a paraneoplastic syndrome
Term
Pink pathes on knuckles
Definition
Gottron's Papules (paraneoplastic)
Term
Hyponatremia, Cushings: what cancer?
Definition
Small cell/lung (SIADH)
Term
Hypercalcemia + secondary polycythemia: what cancer?
Definition
Renal cell adenocarcinoma
Term
Hypoglycemia or secondary polycythemia
Definition
Hepatocellular carcinoma
Term
Hypercalcemia or Cushings: what tumor?
Definition
medullary carcinoma of thyroid. marker can become amyloid.
Term
Markers of testicular cancer
Definition
AFP, hCG. AFP with yolk sac tumor(also hepatocellular carcinoma).
Term
Light chain spike
Definition
Bence-Jones protein; multiple myeloma.
Term
Marker for ovarian cancer
Definition
CA125
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