Term
What are the definitions of personality disorder? |
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Definition
Patterns of inflexible and maladaptive personality traits that cause subjective distress and significant impairment in social or occupational functioning Multiple traits deviate markedly from cultural expectations manifesting in cognition, affectivity, impulse control, and empathy Deviations are stably present, enduring, since adolescence or early adulthood, and pervasive |
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Term
How common are personality disorders? |
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Definition
30%-50% of psychiatric outpatients 15% of psychiatric inpatients are General population with 10%-13% prevalence |
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Term
How doe personality disorders impact treatment? |
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Definition
Affect prognosis and treatment response of Axis I disorders Often respond less well to treatment Associated with poor compliance Characteristics are manifested in the treatment relationship |
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Term
What biochemical abnormalities are common in personality disorders? |
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Definition
Increased dopaminergic function High percent of family history of schizophrenia Abnormalities in serotonin appears to mediate behavioral inhibition, borderline and antisocial personalities Much higher concordance in monozygotic twins Often associated with a hxof sexual and physical abuse |
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Term
How are personality disorders diagnosed? |
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Definition
Patients generally come into treatment with another complaint Need a thorough personal and social history Look for problems in several domains of life Get collateral information Do not rush to make a diagnosis |
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Term
How are personality disorders treated? |
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Definition
Traditionally believed to be resistant to change Quite variable in their course Cognitive-behavioral therapy Identifying internal mental schemes which misidentify situations or aspects of themselves and modifying them Pharmacotherapy |
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Term
What is included in cluster A of personality disorder patients? |
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Definition
Considered eccentric (“Weird”) Paranoid Schizoid Schizotypal |
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Term
What is included in cluster B of personality disorder patients? |
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Definition
Considered dramatic (“Wired”) Antisocial Borderline Histrionic Narcissistic |
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Term
What is included in cluster C of personality disorder patients? |
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Definition
Considered anxious (“Worried”) Avoidant Dependent Obsessive-Compulsive |
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Term
What are the characteristics of paranoid personality disorder? |
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Definition
Long history, rarely seek treatment Usually manages to appear together and undistressed Central feature a pervasive and unwarranted mistrust of others DDX: paranoid schizophrenia, delusional disorder, schizotypal personality |
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Term
What causes paranoid personality disorder? |
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Definition
Psychoanalytic theories suggest person was object of excessive parental rage or repeatedly humiliated by others leading to feelings of inadequacy and vulnerability Hostility and rage projected onto others Some genetic evidence of a relation to Delusional disorder |
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Term
What is the primary defense mechanism in paranoid personality disorder? |
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Definition
Primary defense mechanism of Projection |
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Term
How is paranoid personality disorder treated? |
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Definition
Mistrust usually leads to avoidance of psychiatric treatment Maintain a respectful, straightforward and non-intrusive style Aim at building trust Apologize when accused of a fault Avoid being overly warm or excessively interested Group and cognitive-behavioral therapies are generally resisted Antipsychotic medications if patient decompensates into psychosis |
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Term
What are the characteristics of Schizoid personality disorder? |
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Definition
Characterized by a profound defect in the ability to relate to others Little or no desire for relationships with others Socially isolated Often retreat into elaborate fantasy world Associated with schizotypal disorder, M>F Medical illness very upsetting, may deny treatment |
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Term
What causes Schizoid personality disorder? |
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Definition
Noted in adults who experienced cold, neglectful and ungratifying relationships in early childhood Constitutional factors may include childhood pattern of shyness and may be inherited May also be in the genetic spectrum with schizophrenia |
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Term
How is Schizoid personality disorder treated? |
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Definition
Rarely seek treatment Do not see the value of a relationship with a therapist May come for treatment of depression or brought by others May only tolerate a supportive type therapy aimed at a resolution of a crisis Alliance facilitated by an interested and caring attitude Avoid early interpretation or confrontation Cognitive-behavioral to encourage social involvement Group therapy possible with focus on social skills |
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Term
What are the characteristics of Schizotypal personality disorder? |
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Definition
Cognitive and perceptual distortions: ideas of reference, bodily illusions, unusual telepathic and clairvoyant experiences Behave in an eccentric manner Speech is often odd and idiosyncratic Affect constricted or inappropriate Socially uncomfortable and isolated with few friends Tend to be suspicious |
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Term
What causes Schizotypal personality disorder? |
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Definition
Increased incidence of each other in families Increased ventricular to brain ratio on CT Increased CSF volume Higher CSF homovanillic acid levels Impaired smooth-pursuit eye movements Impaired performance on tests of executive function suggesting altered precortical function |
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Term
How is Schizotypal personality disorder treated? |
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Definition
Usually avoid psychiatric treatment May be brought in when they become depressed or overtly psychotic Difficult to establish an alliance or tolerate exploratory techniques Supportive relationship that counters cognitive distortions and ego-boundary problems may be useful Emphasis on social skills Low dose anti-psychotics may help with anxiety and psychosis-like features |
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Term
What are the characteristics of antisocial personality disorder? |
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Definition
Long-standing pattern of socially irresponsible behaviors that reflects a disregard for the rights of others Lack of remorse over the harm they cause others Impulsivity or failure to plan ahead Irritability and aggressiveness Must be 18 years with Conduct Disorder before age 15 A subgroup takes sadistic pleasure in being harmful Associated with a high rate of substance abuse |
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Term
What causes antisocial personality disorder? |
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Definition
Twin and adoption studies indicate genetic predisposition Impulsive and aggressive behaviors may be mediated by abnormal serotonin transport Early family life often consisted of absent, assaultive or inconsistent parenting Families often have substance abusing and/or antisocial members Men>Women, symptoms lessen with age Tend to die early due to suicides, accidents, homicides, and substance abuse |
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Term
How is antisocial personality disorder treated? |
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Definition
Important to recognize antisocial individuals to avoid uncritical acceptance and disruptive behaviors Little evidence for successful treatment Little evidence for successful treatment Highly structured group residences Some may be able to form a therapeutic alliance Mood stabilizing drugs and antidepressants Avoid addictive substances Some may have ADHD, treat carefully Cognitive-behavior therapy for motivated |
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Term
What are the characteristics of borderline personality disorder |
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Definition
Demanding search for nurturance Instability and dysfunction in affective, behavioral and interpersonal domains Severely impaired capacity for attachment Maladaptive behavior patterns related to separations Alternate between idealization and devaluation in intense relationships Intense abandonment fears lead to rage, self-destructive behavior, guilt tripping, suicide attempts |
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Term
What causes borderline personality disorder? |
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Definition
Psychoanalytic theories focus on early parent-child interaction Maternal mismanagement at ages 2-3 Prevent efforts to become autonomous Exaggerated maternal frustration Inattention to the child’s emotions and attitudes Traumatic early abandonment Physical abuse and sexual abuse in the context of sustained neglect Development of enduring rage and self-hatred Lack of secure attachment Twin studies show 69% heritability with traits Abnormal serotonin probably involved |
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Term
How is borderline personality disorder treated? |
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Definition
High utilizers of psychiatric and emergency services Extremely difficult to treat Frequent idealization and devaluation “splitting” Therapists often develop intense countertransference Intense psychotherapy has been method of choice Pharmacological management aimed at specific problems Avoid benzodiazepines Cognitive-behavioral interventions and group therapy frequently helpful Dialectical behavior therapy (DBT) combines behavioral weekly treatment with twice a week group therapy |
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Term
What are the characteristics of histrionic personality disorder? |
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Definition
Central is over-concern with attention and appearance Underlying insecurity about their value Inappropriate seductive behavior or provocative dress Flamboyant acts or self-dramatizing behaviors Effusive but labile and shallow range of emotions Overly impressionistic and given to hyperbolic descriptions that are lacking in detail or facts Can be very suggestible and easily influenced by others Consider relationships to be more intimate than they are |
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Term
What causes histrionic personality disorder? |
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Definition
Psychoanalytic theory: Originates in the oedipal phase of development An overly eroticized relationship with the opposite sex parent is unduly encouraged Child fears the loss of or retaliation by the same sex parent Research suggests there is a biogenetically determined temperament |
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Term
How is histrionic personality disorder treated? |
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Definition
Individual psychodynamic psychotherapy or analysis remains the cornerstone Aim at helping increase awareness Stay with here and now rather than reconstruction of childhood experiences Idealization and eroticism brought into therapy Caregivers should be supportive and allow for affective ventilation |
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Term
What are the characteristics of narcissistic personality disorder? |
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Definition
Grandiose self-esteem and importance Intense reactions when self-image is damaged When self-image damaged react by becoming devaluative or rageful May become depressed leading to seeking help Often distant in relationships, try to appear self-sufficient and often exploit others DSM-IV focuses on the arrogant, socially conspicuous forms Lack empathy and unwilling to recognize or identify with the feelings or needs of others |
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Term
What causes narcissistic personality disorder? |
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Definition
Little scientific evidence Psychoanalytic theories propose develops in persons who have had their fears, failures or dependency needs responded to with criticism, disdain or neglect during childhood Leads to becoming contemptuous of such reactions in themselves and others and therefore unable to see others as sources of comfort or support |
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Term
How is narcissistic personality disorder treated? |
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Definition
Individual psychodynamic psychotherapy Aim at conveying empathy for patient’s sensitivity and disappointments Allows for a positive idealized transference Vulnerability should be addressed early and directly Very difficult as they resist self-reflection Entitlement feelings get in the way |
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Term
What are the characteristics of avoidant personality disorder? |
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Definition
Excessive anxiety and discomfort in social situations and intimate relationships Strongly desire relationships but fear being ridiculed, criticized, rejected or humiliated Low self-esteem and hypersensitivity to negative evaluation by others Lead constricted lives and avoid new activities |
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Term
What causes avoidant personality disorder? |
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Definition
Develops from parental rejection and censure From early life experiences that lead to an exaggerated desire for acceptance or an intolerance of criticism Children as young as 21 months can show physiological arousal and avoidant traits in social situations |
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Term
How is avoidant personality disorder treated? |
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Definition
May be difficult to engage Psychotherapy with supportive techniques and sensitivity to protective defenses Be aware of potential countertransference reactions Assertiveness and social training may be helpful Cognitive techniques to gently challenge beliefs Group therapy May see some improvement with SRI’s Short term use of low dose anxiolytics |
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Term
What are the characteristics of dependent personality disorder? |
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Definition
Excessive need to be cared for by others Submissive and clinging behaviors and fears of separation Doubt their abilities and judgment View others as stronger and more capable Low self-esteem and self-doubt lead them to avoid positions of responsibility Great effort to maintain dependent relationships |
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Term
What causes dependent personality disorder? |
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Definition
May result from either over or under indulgence during oral phase (birth to age two) Subsequently more support for under-indulgence No specific association between feeding or other oral habits and dependent behavior in adulthood Perhaps more from prohibition of independent behaviors Twin studies have monozygotic twins more similar on scales measuring submissiveness than dizygotic Cultural and social factors |
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Term
How is dependent personality disorder treated? |
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Definition
Often present with depression or anxiety related to loss of a dependent relationship Respond well to various forms of psychotherapy Exploration of fears of independence Encourage increased self-esteem, assertiveness and independent functioning Desire to help may reinforce dependence Group and cognitive-behavioral therapies Couple and family therapy may be helpful |
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Term
What are the characteristics of obsessive-compulsive personality disorder? |
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Definition
Excessively orderly, neat, punctual, organized and overly conscientious Extreme perfectionism which interferes with task completion and delegation Over-work at the expense of leisure activities and relationships Severe superego, “I should” Overly concerned with control including their emotions and others Difficulty expressing emotions, appear distant Difficulty discarding worn-out or worthless objects Miserly toward self and others |
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Term
What causes obsessive compulsive personality disorder? |
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Definition
Related to autonomy Excessive parental control Criticism and shaming Constitutional factors such as excessive rage leading to power struggles with others are possible |
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Term
How is obsessive compulsive personality disorder treated? |
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Definition
Difficult to treat: Excessive intellectualization Difficulty expressing emotion Often respond to psychoanalytic type therapies Therapists must be active Avoid being drawn into interesting but affectless discussions Focus on feelings that are being avoided Power struggles offer opportunities to address the excessive need for control Cognitive techniques to diminish need for control and perfection Dynamically oriented groups that focus on feelings |
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Term
What are the characteristics of normal anxiety? |
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Definition
Fear resulting from the perception of an external environmental danger Alerts the individual to prepare for defense Provides motivational force Anxiety arising from internal impulses that are a threat to the person’s sense of well-being |
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Term
What are the characteristics of pathological anxiety? |
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Definition
Ineffective adaptation to a naturally occurring threat Becomes pathological when functioning is disrupted Worry, demoralization Can manifest as cardiac, respiratory, gastrointestinal or neurological symptoms |
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Term
What biologic findings are common in patients with panic or phobic disorders? |
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Definition
Greater cardiac and respiratory reactivity during sleep Sodium lactate infusion and breathing CO2 may induce respiratory alkalosis and exaggerated brain elevations of brain lactate and elicit panic attacks Dopamine receptors in the prefrontal cortex may be involved in avoidance conditioning Serotonin system may be dysregulated in panic disorder |
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Term
What is the relay center for the body's alarm system? |
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Definition
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Term
How is the Hypothalamic-Pituitary-Adrenal Axis involved in anxiety? |
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Definition
Acute stress triggers release of Corticotrophin Releasing Factor (CRF) from the paraventricular nucleus of the hypothalamus CRF increases Adrenocorticotrophic Hormone (ACTH) and cortisol levels Cortisol helps orchestrate the body's stress response |
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Term
Which endocrine disorders can cause anxiety? |
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Definition
Pheochromocytoma Thyroid dysfunction Pituitary dysfunction Adrenal disorders |
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Term
Which neurological disorders can cause anxiety? |
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Definition
Head trauma Neurosyphilis Seizure disorder CNS neoplasms |
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Term
What toxic and metabolic disorders can cause anxiety? |
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Definition
Alcohol or sedative withdrawal Stimulant intoxication Sympathomimetic agents Cannabis B12 deficiency Hypoxia Ischemia Anemia |
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Term
What autoimmune disorders can cause anxiety? |
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Definition
Systemic lupus erythematosis Temporal arteritis Polyarteritis nodosa |
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Term
What complications are associated with anxiety disorders? |
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Definition
Men with panic disorder have twice the expected death rates, mostly cardiovascular and suicide Overall increased rate of alcoholism Social phobias Decreased educational attainment Higher rate of teenage pregnancy Higher rate of marital violence |
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Term
What is classical conditioning? |
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Definition
A person learns to associate a neutral object or situation with something that naturally results in a fear response |
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Term
What is operant conditioning? |
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Definition
A response is rewarded or punished by the environment and thus results in an increase or decrease of that response Uses positive or negative reinforcement |
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Term
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Definition
Unacceptable thoughts, impulses or desires are kept out of conscious reach When the psychic energy attached to these elements becomes too great to hold back, they find there way into awareness in disguised form, leading to anxiety and panic |
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Term
What are the basic guidelines for screening for anxiety disorders? |
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Definition
Get a good description of the anxiety symptoms Inquire about associated symptoms Take a life history Ask about patient’s theories about symptoms Obtain a complete medical history Maintain a calm, reassuring demeanor Avoid expressing irritation or impatience with the patient |
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Term
How is anxiety disorder associated with depression? |
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Definition
Symptoms often overlap High rate of comorbidity |
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Term
What are the criteria defining a panic attack? |
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Definition
A discrete period of intense fear or discomfort, in which 4(+) of the following develop abruptly & peak w/in 10 min: Palpitations, accelerated HR, Sweating, Trembling or shaking, Sensations of shortness of breath or smothering, Feeling of choking, Chest pain or discomfort, Nausea or abdominal distress, Feeling dizzy, unsteady, lightheaded, or faint, Derealization or depersonalization, Fear of losing control or going crazy, Fear of dying, Parasthesias, Chills or hot flushes |
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Term
What are the characteristics of agoraphobia? |
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Definition
Anxiety about places from which escape might be difficult or where help might not be available in the event of a panic attack Condition not better accounted for by another psychiatric disorder |
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Term
What are the criteria for agoraphobia without panic disorder? |
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Definition
The presence of agoraphobia related to fear of developing panic-like symptoms Criteria have never been met for panic disorder |
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Term
What are the criteria for panic disorder? |
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Definition
Recurrent unexpected Panic Attacks At least 1 of the attacks has been followed by 1(+)mo of 1(+) of the following: Persistent concern about having another attack Worry about the implications of the attack or its consequences Significant change in behavior related to the attacks |
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Term
How often do panic attacks occur in panic disorder? What does it often present with? |
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Definition
Highly variable Several panic attacks per day to twice per year Often comorbid with Major Depressive Disorder and other anxiety disorders, arrhythmias, hyperthyroidism, asthma, COPD, irritable bowel syndrome Increased prevalence of mitral valve prolapse, thyroid disease Higher concordance in monozygotic twins |
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Term
What are the most common symtoms in panic disorder? |
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Definition
Palpitations* Fatigue SOB Nervousness Chest pain Siging Dizziness, fainting, apprehensiveness Headache, parasthesias |
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Term
What does panic disorder usually appear? |
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Definition
Onset late adolescence to mid 30’s Usually chronic, but waxing and waning First-degree relatives have 8x risk of PD |
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Term
What are the different patterns of anxiety? |
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Definition
Panic attacks Anticipatory anxiety During panic; worry about dying, losing control, having a heart attack Dyspnea, palpitations, lightheaded Avoid closed spaces or being alone. Seek reassurance |
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Term
How are panic disorders treated? |
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Definition
Primary: relaxation training, cognitive behavioral pyschotherapy, SSRI's and SNRI's Secondary: TCA's, benzodiazepines Tertiary: MAOI's, anticonvulscants Adjuncts: Buspirone, beta blockers |
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Term
What relaxation techniques can be used to treat panic disorders? |
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Definition
Visual Imagery Diaphragmatic Breathing Autogenic training (relaxing your body through suggestion, focus a body part to relax it) Progressive Muscle Relaxation (focus on tension to relaxation) Yoga Meditation |
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Term
What does cognitive therapy address when used to treat panic disorders? |
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Definition
Negative automatic thoughts/cognitive distortions that help to maintain the anxiety Catastrophizing: exaggerating a potential problem into a catastrophe Generalization Overestimating the probability of a negative outcome |
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Term
What are the criteria for specific phobia? |
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Definition
Marked and persistent excessive or unrealistic fear, cued by the presence or anticipation of an object or situation Exposure to the phobic stimulus provokes an immediate anxiety response The person recognizes that the fear is excessive or unreasonable In children, the duration is at least six months More common in lower socioeconomic classes and unmarried |
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Term
How are specific phobias treated? |
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Definition
First-line: Cognitive-behavioral therapy Second-line: PRN Benzodiazepines |
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Term
What are common somatic complaints associated with social anxiety disorder? |
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Definition
Stuttering Blushing Palpitations Sweating Shaking/trembling |
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Term
What are the characteristics of social anxiety/phobia disorder? |
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Definition
Comorbid anxiety disorders, substance abuse, major depressive disorder common Marked and persistent fear of one or more social or performance situations Exposure to the feared social situation provokes an anxiety response The person recognizes that the fear is excessive or unreasonable In children, the duration is at least six months |
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Term
How is social anxiety disorder associated with considerable impairment? |
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Definition
Lowers potential wages, probability of college graduation, and of professional, technical or managerial employment |
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Term
What are the patterns of anxiety in social anxiety disorder? |
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Definition
Panic attacks Anticipatory anxiety Fear of embarrassment and negative evaluation Blushing, sweating, trembling Avoid public speaking or social interaciton |
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Term
How is social anxiety disorder managed? |
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Definition
Primary: Psychotherapy - systematic desensitization, flooding, cognitive therapy. SSRI’s and SNRI’s Secondary: MAOI’s, Benzodiazepines, Beta blockers (performance anxiety) |
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Term
How is cognitive therapy used to treat social anxiety disorder? |
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Definition
Addresses negative automatic thoughts/cognitive distortions which: Help to maintain the anxiety Catastrophizing: exaggerating a potential problem into a catastrophe Generalization: if one person doesn’t like my lecture I’ll never be a good speaker” Overestimating the probability of a negative outcome |
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Term
OCD is often comorbid with what other conditions? |
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Definition
Major Depressive Disorder M = F but onset earlier in men |
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Term
What are the criteria for OCD? |
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Definition
Either obsessions or compulsions At some point, the person recognizes that the obsessions or compulsions are excessive or unreasonable (does NOT apply to children) The obsessions or compulsions cause marked distress, are time consuming If another Axis I disorder is present, the content of the obsessions or compulsions are not restricted to it |
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Term
What defines an obsession? |
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Definition
Recurrent thoughts, impulses or images that are experienced, at some time during the disturbance, as intrusive and inappropriate, and that cause marked anxiety or distress The thoughts, impulses or images are not simply excessive worries about real life problems The person attempts to ignore or suppress such thoughts, impulses or images, or to neutralize them with some other thought or action The person recognizes that the thoughts, impulses or images are a product of his own mind |
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Term
What defines a compulsion? |
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Definition
Repetitive behaviors or mental actions that the person feels driven to perform in response to an obsession, or according to rules that must be applied rigidly The behaviors or mental acts are aimed at preventing or reducing stress or preventing some dreaded event or situation; however, these behaviors or mental acts either are not connected in a realistic way |
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Term
What kind of biological findings are often present in OCD patients? |
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Definition
Dysfunction of the Corticostriatal circuit Orbitofrontal cortex Caudate nuclei Globus pallidus Symptoms may occur in neurological disorders that involve the basal ganglia (Huntington’s disease) |
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Term
What is the pattern of anxiety in OCD patients? |
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Definition
Panic attacks Anticipatory anxiety Obsessive fears of contamination, causing harm to others, not doing something “just right” Washing/cleaning, checking, ordering, avoiding contaminants, etc. |
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Term
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Definition
First-line: SSRI’s Clomipramine Cognitive-behavioral therapy (Exposure therapy, fear and avoidance hierarchy) Family therapy Second line: Atypical antipsychotic augmentation |
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Term
What are the characteristics of generalized anxiety disorder? |
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Definition
Female>male Usually chronic course, though severity fluctuates Psychiatric treatment uncommon Complications include major depression, substance abuse, panic disorder, associated with significant impairment Excessive anxiety and worry, occurring more days than not for at least six months, about a number of events or activities The person finds it difficult to control the worry |
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Term
What are the criteria for generalized anxiety disorder? |
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Definition
The anxiety and worry are associated with 3(+) of the following (one item in children): Restlessness or feeling keyed up Being easily fatigued Difficulty concentrating Irritability Muscle tension Sleep disturbance |
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Term
What is the pattern of anxiety in generalized anxiety disorder? |
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Definition
Panic attacks Anticipatory anxiety Worries about money, safety, future, relationships Tension, insomnia, restlessness Avoid reminders of worry, seek reassurance |
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Term
How is generalized anxiety disorder treated? |
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Definition
First-line: SNRI’s and SSRI’s Cognitive-behavioral therapy Second-line: Benzodiazepines Buspirone TCA’s Antihistamines (hydroxyzine) |
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Term
What are the characteristics of PTSD? |
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Definition
Men usually combat-related; women usually related to assault or rape Symptom severity fluctuates; usually worse w/stress Outcome better in patients with rapid symptom onset, good premorbid functioning, strong social support, and no psychiatric or medical comorbidity Comorbid anxiety disorders, major depression, and substance abuse common |
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Term
What are the diagnostic criteria for PTSD? |
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Definition
The person has been exposed to a traumatic event in which both of the following were present: Event or events that involved actual or threatened death or serious injury, or a threat to the physical integrity of self or others The person’s response involved intense fear, helplessness or horror The traumatic event is persistently re-experienced in various ways The traumatic event is persistently re-experienced in 3(+) ways Persistent symptoms of increased arousal (not present before the trauma) in 2(+) ways Duration of symptoms is more than one month |
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Term
What are the different types of PTSD? |
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Definition
Acute: duration of symptoms less than 3 months Chronic: duration of symptoms 3 months or more Delayed onset: onset of symptoms is at least six months after the trauma |
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Term
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Definition
First-line SSRI’s and SNRI’s Group therapy Family therapy Cognitive-behavior therapy Second-line Benzodiazepines Prazosin (nightmares and hypervigilance) |
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Term
What are the criteria for acute stress disorder? |
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Definition
The person has been exposed to a traumatic event in which both of the following were present: The person experienced, witnessed, or was confronted with an event or events that involved actual or threatened death or serious injury, or a threat to the physical integrity of self or others The person’s response involved intense fear, helplessness or horror Either while experiencing or after experiencing the distressing event, the individual has 3(+) dissociative symptoms The traumatic event is persistently reexperienced Marked symptoms of anxiety or increased arousal The disturbance lasts for a minimum of two days and a maximum of four weeks and occurs within four weeks of the traumatic event |
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Term
How is acute stress disorder treated? |
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Definition
80 % progresses to PTSD Relaxation training Short course of benzodiazepine Possible beta-blockers |
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Term
What are the characteristics of separation anxiety disorder? |
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Definition
May be precursor to panic disorder May be related to academic problems, or problems with athletic or social skills Approximately 3% schoolchildren |
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Term
What are the diagnostic criteria for separation anxiety disorder? |
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Definition
Developmentally inappropriate and excessive anxiety concerning separation from home or from those to whom the individual is attached, as evidenced by 3(+) manifestations The duration of the disturbance is at least 4 weeks The onset is before age 18. |
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Term
How is separation anxiety disorder managed? |
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Definition
Identify thoughts about anxiety Cognitive restructuring to patient’s worries Parental interventions Educate about anxiety Effect of overprotection in maintaining anxiety Parent management techniques Application of exposure hierarchies |
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Term
How does sexuality change with aging? |
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Definition
Sexual interest does not decline significantly with aging Best predictor of sexual activity in the elderly is availability of a partner Physical changes associated with aging can impact sexual activity Older patients may be uniformed about STD’s |
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Term
What endocrine disorders can cause sexual dysfunction? |
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Definition
Hypothyroidism, hypogonadism, diabetes Causes low libido, impotence, dec vaginal lubrication |
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Term
What vascular disorders can cause sexual dysfunction? |
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Definition
Hypertension, atherosclerosis, stroke, venous insufficiency, sickle cell disorder Causes impotence |
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Term
What neurological disorders can cause sexual dysfunction? |
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Definition
Neuropathy, spinal cord injury, brain injury, multiple sclerosis, temporal lobe epilepsy |
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Term
What surgeries have a higher chance of causing sexual dysfunction? |
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Definition
Prostectomy, colostomy, vaginal repair, episiotomy, amputation |
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Term
What cardiovascular drugs can cause sexual dysfunction? |
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Definition
Methyldopa Thiazide diuretics Clonidine Propanolol Digoxin Clofibrate |
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Term
Which GI drugs can cause sexual dysfunction? |
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Definition
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Term
What anxiolytics cause sexual dysfunction? |
|
Definition
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Term
Why do antipsychotics cause sexual dysfunction? |
|
Definition
Hyperprolactinemia Seen in thioridazine, haloperidol, and quetiapine |
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Term
What are predisposing factors to sexual dysfunction? |
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Definition
Lack of information/experience Unrealistic expectations Negative family attitudes to sex Sexual trauma, rape, incest |
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Term
What are maintaining factors of sexual dysfunction? |
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Definition
Interpersonal issues Family stress Work stress Financial problems Depression Performance anxiety Gender identity conflicts |
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Term
What are the phases of the human sexual response cycle? |
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Definition
Desire phase Excitement phase (foreplay) Plateau phase (period prior to orgasm) Orgasmic phase Resolution phase |
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Term
What is the definition of a sexual desire disorder? |
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Definition
Persistent or recurrent deficiency in or the absence of sexual fantasies and desire for sexual activity Often accompanied by social uneasiness, and lack of self-confidence More common in women |
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Term
What is the definition of sexual aversion disorder? |
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Definition
Persistent and recurrent aversion to and avoidance of genital contact with a sexual partner Some persons have been sexually victimized in the past |
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Term
How do you treat sexual desire disorder? |
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Definition
Testosterone CBT Sensate focus exercises (nondemand pleasuring techniques) Erotic material Masturbation training Marital therapy |
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Term
How do you treat sexual aversion disorder? |
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Definition
CBT Sensate focus exercises (nondemand pleasuring techniques) Erotic material Masturbation training For phobic/panic symptoms, use antidepressant/antianxiety medications |
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Term
What are the characteristics of male erectile disorder? |
|
Definition
Can be primary (rare) or secondary (25% of men), more common with age |
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Term
What are the characteristics of female sexual arousal disorder? |
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Definition
Partial or complete failure to attain or maintain the lubrication/swelling response characteristic of the excitement stage or the complete lack of sexual excitement and pleasure 1/3 of married women May be associated with lack of sexual desire and anorgasmia May result in painful intercourse sexual avoidance |
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Term
How is erectile dysfunction treated? |
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Definition
Phosphodiesterase-5 inhibitors: sildenafil (Viagra), vardenafil (Levitra), and tadalafil (Cialis) Enhance effect of nitric oxide, which relaxes smooth muscles in the penis, increasing blood flow to the penis Sildenafil short-acting, vardenafil lasts up to a day, tadalafil lasts up to 3 days Alprostadil: synthetic prostaglandin E |
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Term
How common is premature ejaculation disorder? |
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Definition
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Term
How is female orgasmic disorder treated? |
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Definition
Self-stimulation Use of fantasy materials Kegel vaginal exercises (contraction of pubococcygeus muscles) Female controlled intercourse |
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Term
How is premature ejaculation treated? |
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Definition
SSRI’s Stop-start technique Squeeze technique |
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Term
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Definition
Genital pain associated with sexual intercourse in men or women Rare in men Not diagnosed when pain is from vaginismus |
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Term
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Definition
Recurrent or persistent involuntary muscle contractions of the perineal muscles surrounding the vagina when penetration by a penis, finger, tampon, or speculum is attempted Muscle contractions may occur even when penetration is anticipated Sexual desire and orgasmic potential may be unimpaired More common in younger women |
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Term
How are sexual pain disorders treated? |
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Definition
Ensure sufficient lubrication Treat any underlying gynecological problem Training to have orgasm by masturbation Psychotherapy Relaxation techniques Hegar dilators for vaginismus |
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Term
What are psychological causes of sexual dysfunction? |
|
Definition
Chronic stress Anxiety or depression Fear of impregnation Fear of rejection by partner |
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Term
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Definition
Usually involves couples Education about normal sexual functioning Understanding attitudes and improving communication Sensate focus exercises A series of assignments to be carried out in private CBT to correct dysfunctional beliefs |
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Term
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Definition
Recurrent, intense sexually arousing fantasies, sexual urges or behaviors occurring over a period of at least six months generally involving either nonhuman objects, suffering or humiliation, or children or other nonconsenting partners |
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Term
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Definition
Deviant patterns of arousal become paired with masturbation Can occur in brain injuries or dementia, poor impulse control Dilation of temporal horns seen in pedophilia |
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Term
How do Paraphilias progress? |
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Definition
Usually established in adolescence Most persons are heterosexual Persons may have > 1 paraphilia Co-occurring psychiatric disorders common Tend to be chronic but tend to vary in frequency of expression and severity May have normal sex lives with partner or spouse aside from paraphilia |
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Term
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Definition
Exposure of one’s genitals to a stranger 1/3 of sexual offenders referred for treatment Person masturbates while exposing his genitals Generally no attempt at having sexual activity with the stranger May occur during dementia |
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Term
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Definition
Sexual arousal from a physical object (not a vibrator) Often rubber garments, women’s underclothing, and high-heeled shoes as objects of gratification Contact with the object produces arousal, which is followed by masturbation Person may spend considerable time seeking desired objects |
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Term
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Definition
Touching or rubbing against a nonconsenting person May involve rubbing genitals against victim’s thighs or buttocks or touching genitals or breasts with hands Tends to occur in crowded places from which the person can readily escape Most common in 15- to 25- year age group |
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Term
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Definition
Sexual activity with a prepubescent child, generally age 13 or younger Individual must be 16 yo and at least 5 years older than the child Pedophiles generally report an attraction to children of a particular age Experiencing distress about thoughts and fantasies is not required for the diagnosis Tends to begin in adolescence and to be chronic |
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Term
What is Transvestic fetishism? |
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Definition
Cross-dressing by a man in women’s clothing Begins at puberty Early on, person experiences cross-dressing as sexually stimulating As person gains confidence, clothes may be worn in public Tends to have chronic course |
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Term
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Definition
Act of observing unsuspecting persons, usually strangers, who are naked, in the act of disrobing, or engaging in sexual activity The looking is for sexual excitement and no sexual contact with the observed person is sought Often an expression of sexual curiosity in adolescents and typically has onset before 15 years of age Tends to have chronic course |
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Term
What is sexual masochism and sexual sadism? |
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Definition
Masochism involves sexual fantasies, urges, or behaviors of being humiliated, bound, or otherwise made to suffer, causes significant distress or impairment Sadism involves sexual fantasies, urges or behaviors in which psychological or physical suffering (including humiliation) of a victim is sexually exciting to the person. The person has acted on the urges with a nonconsenting person, or the urges or fantasies cause marked distress or interpersonal difficulty |
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Term
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Definition
Paraphilia involving feces |
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Term
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Definition
Paraphilia involving desire to achieve altered state of consciousness secondary to hypoxia |
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Term
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Definition
Paraphilia involving behaving as though one were an infant |
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Term
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Definition
Paraphilia involving dead persons |
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Term
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Definition
Paraphilia involving enemas |
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Term
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Definition
Paraphilia involving focusing on oral-genital contact to the exclusion of intercourse |
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Term
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Definition
Paraphilia involving focusing on one part of the body to the exclusion of all else (e.g., feet) |
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Term
What is telephone scatologia? |
|
Definition
Paraphilia involving obscene phone calls |
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Term
How are paraphilias managed? |
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Definition
Masturbatory satiation (boring the pt with his own deviant fantasies) Covert sensitization (replacing fantasies with unpleasant images) Masturbatory conditioning Social skills conditioning Relaxation training CBT Some meds, none are FDA-approved |
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Term
What is gender identity disorder (transexualism)? |
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Definition
A strong and persitent cross-gender identification Often a desire to become a member of the opposite sex Individuals have a sense of inappropriateness about their assigned gender Usually begins in childhood Prevalence 1 in 30000 men and 1 in 100000 women Mood disorders, substance abuse and personality disorders are frequently comorbid Many seek hormonal treatment and request sex reassignment surgery |
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Term
What factors lead to good adjustment after sex-change surgery in people with gender identity disorder? |
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Definition
Lifelong cross-gender identification Ability to “pass” convincingly as a member of opposite sex Good social support Education and steady job |
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Term
What are the purposes served by monogamy? |
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Definition
Preserves couples mental, physical, social, and economic health Preserves family structure to facilitate children’s emotional development Preserves continuity of families lives |
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Term
What is noncommercial problematic sex? |
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Definition
Love affairs Hookups Friends with benefits Swinging |
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Term
What is commercial problematic sex? |
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Definition
Prostitutes Lap dancers/strippers Masseuses with “happy endings” |
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Term
How psychotherapy for sexual diseases approached? |
|
Definition
Initial, from substance abuse Addiction is a disease, not a moral failing Subsequent Personal responsibility for better choices and impulse control, expressing feelings and coping Focus on understanding the motivations for the behaviors Learning new ways of dealing with life issues |
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Term
What drugs can be used to treat excess sex drives? |
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Definition
SSRI Gonadotrophin-release factor inhibitor (leuprolide) Progesterone |
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Term
What are the diagnostic criteria for adjustment disorders? |
|
Definition
The development of emotional or behavioral symptoms in response to an identifiable stressor occurring within three months of the onset of the stressor Symptoms cause marked distress that is in excess of what would be expected from exposure to the stressor or significant impairment in functioning |
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Term
What is the difference between acute and chronic adjustment disorders? |
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Definition
Acute = >6mo Chronic = <6mo in response to a chronic stressor or to a stressor that has enduring consequences When disturbance is longer than six months, should presumably meet criteria for another disorder |
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Term
What are the subtypes of adjustment disorders? |
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Definition
Can be associated with: Depressed mood Anxiety Mixed anxiety/depressed mood Disturbance of conduct Mixed disturbance of emotions and conduct Unspecified: ex. for a person who is having difficulty functioning at work |
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Term
What are the characteristics of adjustment disorders? |
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Definition
Typically lasts days to weeks 43% of adolescents with adjustment disorders later are diagnosed with other psychiatric illness Adolescents more likely to be suicidal Clinicians may have a bias toward diagnosing adjustment disorders in adolescents If the symptoms meet criteria for another Axis I psychiatric disorder, it would be the correct diagnosis, even in the presences of a stressor Adjustment disorders more likely to occur in patients with maladaptive styles, such as those with personality disorders |
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Term
What are the common stressors causing adjustment disorders in children? |
|
Definition
Illness Parental divorce Moves Birth of a sibling Poverty |
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Term
What are the common stressors causing adjustment disorders in adults? |
|
Definition
Illness Marital problems Moves/placements Job problems Legal problems Cancer patients: about 25% have persistent anxiety and depressive symptoms for weeks to months |
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Term
What do you do when an adjustment disorder is comorbid for depression? |
|
Definition
Depression should be treated, do not underestimate the morbidity caused by depression |
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Term
How are adjustment disorders managed? |
|
Definition
Individual psychotherapy, typically supportive psychotherapy Group psychotherapy Symptomatic treatments: Hypnotic for insomnia Short course of benzodiazepine for anxiety |
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|
Term
What mental health factors during pregnancy influence infant outcomes? |
|
Definition
Exposure to illness during pregnancy Impact of illness during pregnancy on obstetrical outcome Exposure to treatment during pregnancy Impact of illness on infant Exposure to treatment during breastfeeding |
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Term
How are medication use decided during pregnancy? |
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Definition
Medications used when risk to mother and fetus from disorder outweigh the risks of pharmacotherapy No decision is risk free |
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Term
What are potential effects of maternal anxiety during pregnancy on infant outcome? |
|
Definition
Prematurity Low birth weight Low Apgar scores High cortisol levels in children |
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Term
What are potential effects of maternal depression during pregnancy on infant outcome? |
|
Definition
Low birth weight Intrauterine growth retardation Childhood IQ negatively associated with duration of depression in pregnancy |
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Term
What are potential effects of maternal psychosis during pregnancy on infant outcome? |
|
Definition
High risk pregnancy in many ways Thought and behavioral disorganization May have delusions about fetus/infant Suicide |
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|
Term
What is the treatment of choice for mild to moderate depression during pregnancy? |
|
Definition
Psychotherapy May be especially important during first pregnancy and women with limited support systems |
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|
Term
What is required to detect teratogenesis with medication? |
|
Definition
Must exceed 3% baseline and/or must have distinctive pattern |
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|
Term
What are the FDA pregnancy categories? |
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Definition
A= Absence of risk B= No risk in animals or risk in animals not shown in human controlled studies C= risk in animals, no human controlled studies; or no studies available D= need for drug justifies known risk X= Contraindicated in pregnancy |
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|
Term
What drugs carry a low risk of teratogenesis? |
|
Definition
Typical antipsychotics: thioridizine, perphenazine, trifluoperazine, fluphenazine, haloperidol Antidepressants: TCA’s, most SSRI’s, bupropion, mirtazapine, venlafaxine Mood stabilizing medication: lamotrigine <3% risk of cleft palate |
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Term
What risk is associated with the use of atypical antipsychotics during pregnancy (clozapine, olanzapine, quetiapine, risperidone, aripiprazole, ziprasidone)? |
|
Definition
Concerns regarding gestational diabetes, weight gain, infant birth rate May be associated with lower motor skills and reflexes at six months after birth |
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Term
Lithium has what known teratogenic effects? |
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Definition
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|
Term
Carbamazepine has what known teratogenic effects? |
|
Definition
Cranial-facial defects, spina bifida |
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|
Term
Valproic acid has what known teratogenic effects? |
|
Definition
Cranial-facial defects, spina bifida, autism?, diminished cognition |
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|
Term
What are the consequences of untreated maternal depression during pregnancy? |
|
Definition
Untreated maternal depression = diminished body and head growth SSRI-treated depression = less depressive symptoms, no effect on body growth, but diminished head growth SSRIs have no association with stillbirth or neonatal mortality |
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Term
How does lithium affect labor and delivery? |
|
Definition
Can cause obstructed labor due to goiter in the baby |
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|
Term
How do benzodiazepines affect labor and delivery? |
|
Definition
Can cause sedation in neonate |
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|
Term
How do SSRI’s/SNRI’s affect labor and delivery? |
|
Definition
Potential for discontinuation syndrome (paroxetine, venlafaxine); persistent pulmonary hypertension associated with late trimester exposure to an SSRI; increased risk of prematurity? |
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|
Term
What are the long-term neurobehavioral effects of prenatal exposure to an antidepressant? |
|
Definition
Though limited data, no clear effects noted In small study, no significant effects on muscle tone, reflexes or motor skills at six months |
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|
Term
When should you consider discontinuing antidepressant therapy during pregnancy? |
|
Definition
Only one episode At least six months of good functioning No strong family history No current stressors Good support system Avoid switching meds during pregnancy, depression during pregnancy strongest predictor of postpartum depression |
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|
Term
How do you treat bipolar disorder during pregnancy? |
|
Definition
If mild to moderate: consider tapering from mood stabilizers prior to pregnancy, reintroduce as needed or during 2nd trimester Lithium may be safest alternative for women dependent on mood stabilizers |
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|
Term
What are the long-term neurobehavioral effects of prenatal exposure to an antipsychotic? |
|
Definition
At six months: Lower muscle tone Less-developed motor skills Reduced reflexes |
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|
Term
What should be screened for when suspecting postpartum depression? |
|
Definition
Anemia Thyroid disease Bipolar disorder Psychosis Delirium |
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|
Term
What are the risk factors for postpartum depression? |
|
Definition
Past history of psychiatric disorder or subsyndromal disease Affective instability during pregnancy coupled with clinical roughening during third trimester History of mood cycling |
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|
Term
What should be kept in mind when treating postpartum disorders with medication? |
|
Definition
All psychotropic medications pass into milk Infant levels are a fraction of maternal levels Long-term effects are unknown |
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|
Term
How does illness affect breast feeding? |
|
Definition
Cortisol readily excreted into breast milk Unknown impact on IgA, IgM, and other constituents of breast milk If breast milk is altered by illness, benefits may not be the same |
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|
Term
What are the risks of not treating postpartum disorders? |
|
Definition
Poor infant care/impaired synchrony Rejection of infant/impaired attachment Suicide/homicide Guilt Poor eating/ maternal self-care |
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|
Term
What meds show no harm during breastfeeding? |
|
Definition
SSRI’s TCA’s Bupropion Venlafaxine Trazadone Atypical antipsychotics |
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Term
|
Definition
Related to thinking, memory, judgment, perception |
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|
Term
What are some examples of ADLs (activities of daily living)? |
|
Definition
Hygiene, ambulation, toileting eating, dressing |
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|
Term
What are some examples of IADLs (instrumental activities of daily living)? |
|
Definition
Shopping, housekeeping, accounting, food/meds, technology |
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|
Term
|
Definition
Objective acquired cognitive dysfunction Displays a dysfunction in ADLs (or IADLs) |
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|
Term
What is mild cognitive impairment? |
|
Definition
Objective cognitive dysfunction No impairment in ADLs 50% develop dementia in 5 years |
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|
Term
What are the risk factors for dementia? |
|
Definition
Increasing age, esp over 65 Low level of education Family history Gene mutations Vascular risk factors: Obesity, Lack of exercise, Diabetes, Hypertension |
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|
Term
What is the most common cause of dementia? |
|
Definition
Alzheimer Disease (50%) Prevalence doubles every 5 years after age 65 |
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|
Term
What are the core features of Alzheimer disease? |
|
Definition
Impaired episodic memory Visuospatial dysfunction Language difficulties |
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|
Term
What makes up plaques in Alzheimer Disease? Where are they found? |
|
Definition
Extracellular Beta-amyloid deposits |
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|
Term
What makes up tangles in Alzheimer Disease? Where are they found? |
|
Definition
Phspho-tau found intracellularly |
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|
Term
What are the three major subtypes of frontotemporal dementia? |
|
Definition
Behavioral Progressive nonfluent aphasia Semantic dementia |
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|
Term
What are the characteristics of behavioral frontotemporal dementia? |
|
Definition
Disinhibition Loss of volition Distractibility Emotional blunting Irritability Poor insight |
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|
Term
What are the characteristics of progressive nonfluent aphasia frontotemporal dementia? |
|
Definition
Impaired language production Effortful speech Poor grammar Reading and writing may be affected Eventual mutism Other functions generally spared |
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|
Term
What are the characteristics of semantic frontotemporal dementia? |
|
Definition
Impaired language comprehension Difficulty naming Fluent speech and normal grammar Reading usually unaffected |
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|
Term
How does Alzheimer Disease appear in neuroimaging? |
|
Definition
Generalized brain atrophy, hippocampal atrophy on CT, abnormal FDG on PET scan |
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|
Term
How does Frontotemporal Demential appear on neuroimaging? |
|
Definition
Atrophy of the frontal lobe, visible in the frontal lobe on a CT scan, abnormal FDG PET scan |
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|
Term
What causes vascular dementia? |
|
Definition
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|
Term
What are the characteristics of cerebral infarctions that lead to vascular edema? |
|
Definition
Single event with residual symptoms Progressive decline due to multiple events Preventable Often associated with other dementias |
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|
Term
How does vascular dementia appear on neuroimaging? |
|
Definition
Infarctions are visible, may be multiple and tiny or few and large. Placement determines effect |
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|
Term
What are the tangible complications of dementia? |
|
Definition
Increased morbidity and mortality Higher costs of living Nursing home and ALF placement |
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|
Term
What are the intangible complications of dementia? |
|
Definition
Lost productivity Family/caregiver stress |
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|
Term
|
Definition
Formal assessment of cognition interpreted in the context of other psychological, social and health factors |
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|
Term
How is neuropsychology used when treating patients suspected with dementia? |
|
Definition
Provides a diagnostic aide A useful baseline to evaluate treatments/progression Can be useful in guiding competency decisions and design interventions. Can be applied in clinical trials |
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|
Term
What clinical cognitive assessments are used physicians? |
|
Definition
Mini-Mental State Examination (MMSE) Montreal Cognitive Assessment (MoCA) |
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|
Term
What clinical cognitive assessments are used neuropsychologists? |
|
Definition
Various styles, “off the shelf” batteries Usually eclectic mix to assess different domains |
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|
Term
What clinical cognitive assessments are used clinical trialists? |
|
Definition
ADAS-Cog Neuropsychological Test Battery Severe Impairment Battery |
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|
Term
What cognitive domains are tested during assessment? |
|
Definition
Premorbid IQ Orientation Attention Processing Speed Memory Language Visuospatial Skills Executive skills |
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|
Term
What is it important to assess various domains? |
|
Definition
Different diseases have their own cognitive “signatures” Some parts of the brain are more vulnerable to certain diseases |
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|
Term
Alzheimer's disease targets what parts of the brain first? How does it progress? |
|
Definition
Limbic networks responsible for episodic memory Attacks the hippocampus and entorhinal cortex, causes anterograde amnesia Progresses to association cortices, cascades neuropsychological impairment by region |
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|
Term
How does memory change in Alzheimer's disease? |
|
Definition
Word learning tests show loss of free recall ability and reduced recognition with cues Impaired consolidation (not ineffective retrieval) Free recall and recognition further impacted by increased sensitivity to interference Reduced semantic clustering affects learning |
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|
Term
What is evaluated in the neuropsychological evaluation? |
|
Definition
Estimation of baseline IQ Various domains: M-S-A-L-V-E Memory Speed of processing Attention Language Visuospatial functiong Executive functioning |
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|
Term
How is the the neuropsychological evaluation interpreted? |
|
Definition
Heirarchical in nature If no attention, or severely reduced speed, needs to be taken into account for interpretation Language and understanding has a major impact Must be flexible in approach |
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|
Term
A patient's clinical history during a neuropsychological evaluation should strive to include input from what other source? |
|
Definition
Partner's report However, sometimes it is important to separate the accounts |
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|
Term
What type of assessment tools are available for neuropsychological evaluations? |
|
Definition
Standardized tests commercially available Free tests of cognition and questionnaires |
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|
Term
What are non-standardized aspects of neuropsychological evaluations? |
|
Definition
Remembering clinician’s name, evidence of fluctuation during assessment, remembering way back to waiting room |
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|
Term
How should neurophsychological tests be standardized? |
|
Definition
Should use appropriate norms Test performance differs by age but also cultural background, and education level Sometimes, normative information is not enough, must screen closely for actual retention or the nature of the naming difficulty Environmental and examiner relationship/rapport are also factors |
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|
Term
What is prodromal/mild cognitive impairment Alzheimer's Disease? |
|
Definition
Some memory loss may occur years prior to the onset of dementia |
|
|
Term
What mental faculties are usually spared with Alzheimer's Disease? |
|
Definition
Digit span forward Vocabulary Information Comprehension Similarities |
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|
Term
A decline in cognition coincides with what other change? |
|
Definition
|
|
Term
What are common neuropsychiatric symptoms associated with Alzheimer's? |
|
Definition
Depression, anxiety, irritability among most frequent |
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|
Term
What pathologies might resemble Alzheimer's Disease but do not display the specific deficit in retrieval necessary for diagnosis? |
|
Definition
Depression Normal pressure hydrocephalus Sleep deprivation |
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|
Term
What is Lewy body dementia? |
|
Definition
A "subcortical" dementia characterized by Parkinsonism, hallucinations, fluctuating cognition, and neuropsychological deficits |
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|
Term
What neuropsychological deficits are present with Lewy body dementia? |
|
Definition
Visuospatial Executive Attention Memory deficit less severe than in AD, qualitatively different, better recall and recognition but deficit in learning |
|
|
Term
Vascular dementia usually presents with impairments in what functions? |
|
Definition
Executive functions Visuoconstructional impairment |
|
|
Term
What functions are spared in vascular dementia? |
|
Definition
|
|
Term
Frontotemporal dementia causes what changes? |
|
Definition
Primarily affects behavior and/or language Memory spared in early stages Can be difficult to test memory due to prominent aphasia or behavioral indifference/disinhibition |
|
|
Term
What biomarkers predict the conversion from mild cognitive impairment to Alzheimer's disease? |
|
Definition
Best prediction of conversion seen on MRI Aβ pathology implies clinical progression but absence does not classify it as benign |
|
|
Term
What are potential reasons Alzheimer's disease is so underdiagnosed? |
|
Definition
The goals of treatment may not be clearly understood Lack of understanding of the importance of treating AD Early signs of AD are subtle and easily missed by physicians Cholinesterase inhibitor therapy can reduce cognitive and functional decline in patients with AD Lack of definitive screening and diagnostic tests Reluctance to acknowledge signs and symptoms |
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|
Term
What are risk factors for Alzheimer's Disease? |
|
Definition
Age Hypertension Hypercholeterolemia Head injury |
|
|
Term
What type of patients should be evaluated for Alzheimer's Disease? |
|
Definition
Patients with identified risk factors Patients with memory or cognitive impairment People brought to attention through an informal complaint Depressed or anxious patients with or without cognitive complaints |
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|
Term
What are the DSM IV criteria for Alzheimer's Disease? |
|
Definition
Memory impairment Impairment in one other domain (aphasia agnosia, apraxia, executive dysfunction) Occupational and social dysfunction Gradually progressive |
|
|
Term
What are the limitations of the DSM criteria for Alzheimer's disease? |
|
Definition
Low specificity 40% of non-AD dementia dx are actually AD Requires presence of dementia prior to diagnosis Many behavioral symptoms precede diagnosis by months or years |
|
|
Term
What are often the first signs and changes associated with Alzheimer's disease that can precede diagnosis by months to years? |
|
Definition
Social withdrawal Depression Day/night reversals |
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|
Term
What is the informant assessment/AD8? |
|
Definition
An 8-item questionnaire that probes for changes from the patient’s previous level of functioning Only minimally affected by age, gender, race, education, or relationship of informant |
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|
Term
How is the informant assessment/AD8 administered? |
|
Definition
Can be done at home by informants Yes/No format, 2 or more positive answers correlate strongly with dementia |
|
|
Term
Why are extensive lab studies recommended as a part of the assessment of dementia? |
|
Definition
Necessary to identify causes of dementia and coexisting conditions that are common in the elderly Depression, vitamin B12 deficiency, and hypothyroidism commonly occur in the elderly, and particularly in patients with suspected dementia |
|
|
Term
What are some causes of memory problems other than dementia? |
|
Definition
Depression Drugs Tumors Infection Subdurals |
|
|
Term
Abnormal TSH and B12 levels found during the assessment of suspected dementia indicates what? |
|
Definition
|
|
Term
Focal signs found during the assessment of suspected dementia indicates what? |
|
Definition
|
|
Term
Parkinsonism found during the assessment of suspected dementia indicates what? |
|
Definition
Dementia with Lewy bodies |
|
|
Term
Tactless and impulsive behavior found during the assessment of suspected dementia indicates what? |
|
Definition
|
|
Term
Amnestic memory defects found during the assessment of suspected dementia indicates what? |
|
Definition
|
|
Term
What are the benefits of early recognition and treatment of dementia? |
|
Definition
Identify entities that would be treated differently Treatments may slow down functional decline Opportunity to participate in research Capacity to decide one’s fate and treatment by the patient |
|
|
Term
What is the original amyloid cascade hypothesis? |
|
Definition
Alzheimer’s is the cumulative product of a series of pathological events that may begin with the deposition of beta-amyloid in the brain |
|
|
Term
What is required for a research diagnosis of Alzheimer's Disease (including pre-dementia)? |
|
Definition
Documented and progressive episodic memory impairment At least 1 biomarker evidence of Alzheimer's disease such as mild temporal atrophy, biparietal hypometabolism, amyloid signals on PET, decreased Aß and increased tau/p-tau int he CSF, or a first degree relative with a APP or PS mutation |
|
|
Term
|
Definition
A legal action to recover money or property, enforce or protect a civil right, prevent or redress a civil wrong The “opposite” of a criminal action |
|
|
Term
|
Definition
A legal process for admitting a mentally ill person to a psychiatric treatment program, usually involuntarily Involves a court or judicial procedure |
|
|
Term
What are other terms that refer to a civil commitment? |
|
Definition
Legal 2000 L2K Involuntary Hold Involuntary treatment Involuntary Committed 72 hour hold |
|
|
Term
After a patient is brought into the ER by EMS, what is the following process of civil commitment in Nevada? |
|
Definition
Initial evaluation to establish whether or not they meet criteria and whether they are medically clear Discharged if no criteria are met and medically clear If medically clear but meet criteria, Legal 2000 is completed and they are transferred to a mental health facility. If medically not clear, admitted first to hospital and not committed |
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|
Term
What is the definition of mental illness according to Nevada? |
|
Definition
Any person whose capacity to exercise self-control, judgement, and discretion in the conduct of his/her affairs and social relations or to care for personal needs is diminished as a result of mental illness to the extent that they present a clear and present danger to self or others, but does not include any person whose capacity is diminished by epilepsy, mental retardation, dementia, delirium, intoxication, addiction, unless a diagnosable mental illness is also present |
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|
Term
A mental hospital should be reserved for what type of patients? |
|
Definition
The seriously mentally ill who are in an acute crisis situation and for whom a treatment is available |
|
|
Term
What is considered "serious mental illness"? |
|
Definition
Schizophrenia and schizoaffective disorders Bipolar disorder, particularly while manic PTSD with exacerbations from stressors Severe personality disorder, particularly borderline and antisocial disorder Major depression with psychotic symptoms, extreme negativity, and suicidal impulses All can be under the influence of drugs or severe stress |
|
|
Term
What is Criteria A for serious mental illness? |
|
Definition
Unable to care for self Sometimes known as “gravely disabled” Can be subsumed under a broad definition of dangerousness to self |
|
|
Term
What is Criteria B for serious mental illness? |
|
Definition
Suicidal actions, threats or intent High risk illnesses include schizophrenia, major depression, bipolar disorder, substance abuse/dependence and personality disorders |
|
|
Term
What are static risk factors for Criteria B? |
|
Definition
Male, single, increasing age, White and Native Americans, prior suicide attempts and family history of suicide |
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Term
What causes Criteria B serious mental illness? |
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Definition
Psychosocial stresses Younger more likely about relationship problems and legal problems Older populations frequently related to declining health and physical illness Other issues relate to financial ruin or shame and failure |
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Term
What is Criteria C for serious mental illness? |
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Definition
Self-mutilation Some will report converts psychic pain into physical pain which is a relief and gives a sense of control Most common in borderline personality Frequently has a manipulative aspect |
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Term
What is Criteria D for serious mental illness? |
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Definition
Danger to others Past history of violence is the best predictor of future violence Obtain as much history as possible and use multiple sources |
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Term
What demographic has a higher risk of Criteria D serious mental illness? |
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Definition
Slightly increased risk of violence in the mentally ill |
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Term
What mental illnesses are most commonly associated with violence? |
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Definition
Schizophrenia Bipolar mania Personality disorders Alcohol and other substance abuse |
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Term
What are common characteristics in patients under Criteria D serious mental illness? |
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Definition
Recent stressors are relationship issues and economic problems such as job loss History of abuse, victimization and family violence predispose Affect states are most important to assess such as fear, anger, confusion and humiliation |
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Term
What is required by the state of Nevada to classify a Criteria D serious mental disorder? |
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Definition
Threats or previous actions must be within 30 days Clinician must judge the dangerousness of the threats or acts rather than the degree of danger represented by the patient’s mental state |
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Term
Why is it the responsibility of the mental health system to attempt to treat antisocial personalities, particularly those classified under Criteria D serious mental disorder? |
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Definition
Police are unlikely to arrest someone for verbal threats |
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Term
What are non-committable patients? |
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Definition
Patients who are intoxicated will resolve much of their suicidal and homicidal ideation once sober Patients experiencing acute crisis due to environmental stressors, will usually calm down Some patients with mental illnesses off their meds Some patients should be referred for detox or substance abuse treatment if they will go voluntarily |
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Term
How often do patients presenting to local ER’s with the initial part of Legal 2000 completed actually receive inpatient care at SNAMHS? |
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Definition
Only about 23% Most others have other problems, are ultimately considered non-committable patients |
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Term
What is the function of medical clearance? |
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Definition
Establishes that patient does not have a medical problem that is causing or significantly contributing to the psychiatric symptoms and that any other medical problem is stable enough for the patient to be admitted to a mental health facility |
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Term
A medical clearance should include what tests? |
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Definition
Pregnancy test in females Urine toxicology screen and BAC |
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Term
What are the possible outcomes for a patient that a physician determines requires commitment and for whom a Legal 2000 has started? |
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Definition
Psychiatric consultation determines: No underlying psychiatric illness Psychiatric symptoms are due to substance disorder, refer to substance abuse program when stable Psychiatric diagnosis generates treatment recommendations that are successful Psychiatric treatment does not lead to improvement before medical clearance, page B of Legal 2000 is completed, committed to a mental health facility |
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Term
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Definition
A legal state and refers to the degree of mental soundness necessary to make decisions about a specific issue or to carry out a specific act |
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Term
When can you assume someone is competent? |
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Definition
All adults are presumed competent unless adjudicated otherwise by a court |
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Term
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Definition
An individual’s ability to make an informed decision |
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Term
Who can make a determination of capacity? |
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Definition
Any licensed physician Frequently done by forensic psychiatrists for many issues such as stand trial or make a will |
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Term
What happens if a person is determined to be lacking capacity? |
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Definition
They may need to be referred for a competency hearing or need to have a guardian appointed |
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Term
Competence is specific to what? |
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Definition
A specific issue in question such as competency to stand trial |
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Term
What competency issues often become points of dispute following an individuals death? |
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Definition
Competency to make a will or enter into a contract such as marriage or real estate |
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Term
What are common causes of a patient's refusal to receive medical treatment? |
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Definition
Patient’s poor understanding of proposed treatment Mental illness may also impair capacity |
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Term
What is informed consent? |
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Definition
Written consent needed for procedures, treatments with risk and research protocols In psychiatry may be for ECT or psychotropic medications |
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Term
What is required for someone to make informed consent? |
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Definition
Comprehension Free or voluntary choice Reliability Requires that the patient has knowledge, is competent and consent is voluntary |
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Term
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Definition
Whether or not a patient demonstrates an understanding of their condition and proposed treatments Educate if necessary and at a language level appropriate to the patient. Patient must know the risks and benefits of treatment |
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Term
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Definition
Decision to accept or reject treatment must be voluntary May be forced due to coercion, unrealistic fears, denial, or mental illness |
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Term
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Definition
The patient’s ability to make a decision and stick to it Some psychiatric conditions such as anxiety or depression may cause indecision and may respond to treatment |
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Term
What are exceptions to informed consent? |
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Definition
Emergency Incompetence or lack of capacity to make decisions that must be made without benefit of the court Consent obtained from a guardian or substitute decision maker Waiver Therapeutic privilege |
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Term
What are potential interruptions that can deny communicating choice and consent? |
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Definition
Impairment of consciousness Mutism Thought disorder Disruption of short memory Severe ambivalence Severe aphasia with inability to write as an alternative |
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Term
What concept of competence is most often referred to in legal cases and statutes? |
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Definition
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Term
What is relevant information? |
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Definition
Refers to capacities include memory for words, phrases, ideas and sequences of information Must comprehend the fundamental meaning and that they have a critical part in decision making |
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Term
What is involved in appreciating the situation and its consequences? |
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Definition
Appreciating the existence of illness, the probable consequences of a treatment or its refusal, and the likelihood of each of a number of consequences |
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Term
What must be distinguished when appreciating the situation and its consequences? |
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Definition
A realistic evaluation of the situation and the reasonableness of the decisions made |
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Term
What can cause a deficiency in the ability to appreciate the situation and its consequences? |
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Definition
Pathological distortion or denial of reality Delusional perceptions of the illness, the treatment or motivations of caregivers |
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Term
What is rational manipulation of information? |
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Definition
Ability to use logical processes to compare the benefits and risks of various treatment options Process of weighing information, frequently multiple options simultaneously, to reach a decision |
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Term
What can impede rational manipulation of information? |
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Definition
Psychotic thought disorder Delirium and dementia Extreme phobia, panic or anxiety Euphoria or mania Depression Anger |
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Term
What determines the level of competence? |
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Definition
Varies with the risk/benefit ratio More favorable the risk/benefit ratio, the lower the standard of competence to consent and the higher the standard to refuse |
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Term
What situations require a particularly high level of competence? |
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Definition
Participation in research studies Refusal of disfiguring surgeries such as amputation may require a court intervention Very unfavorable risk/benefit ratio |
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Term
Who is qualified to evaluate capacity? |
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Definition
Most evaluations can be performed by the attending physician who must be: Conversant in the evaluation of mental status in the medically ill Familiar with the abilities related to competence Aware of the medical implications of the illness and proposed treatment |
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Term
When is a more formal evaluation of capacity required? |
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Definition
When patients behave in a way that their competence comes into question, such as refusal of treatment thought beneficial |
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Term
What is the process of evaluating capacity? |
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Definition
Gather information related to medical situation and psychiatric history Assess the patient’s knowledge and understanding Do a mental status exam focusing on orientation, memory, cognitive skills and presence of delusions and hallucinations Obtain auxiliary information from family, caregivers and nurses Treat reversible conditions and reassess Document thoroughly |
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Term
What is the function of the court regarding issues of capacity and competency? |
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Definition
The court will attempt to reach a balance between protecting patients from bad decisions and maintaining their autonomy In most cases of apparent incompetence, a substitute decision maker is found or appointed and generally the courts will support this approach |
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Term
Patients with a mental illness and an acute medical problem cannot be civilly committed in Nevada until what? |
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Definition
Their medical condition must be stable enough to transfer |
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Term
What is required in the non-emergent situation for treatment of an incompetent patient? |
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Definition
A surrogate decision maker |
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Term
What are the basic guidelines in the approach to treating an incompetent patient? |
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Definition
Use the least restrictive treatment alternative A sitter is generally preferred to physical restraints Careful documentation for physical restraint when necessary Chemical restraint is effective but watch for over sedation |
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Term
Restraint or treatment without a patient’s consent can give rise to liability for what charges? |
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Definition
Battery which is touching another person without consent or justification False imprisonment from when patient is denied the right to move around at will by real or perceived methods of confinement |
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Term
A failure to treat or restrain a patient who is incompetent or behaves in self-injurious fashion leaves you liable for what? |
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Definition
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Term
What are the principles of medical ethics specifically applicable to psychiatry? |
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Definition
A physician shall respect the rights of patients and shall safeguard patient confidences within the constraints of the law Psychiatric records must be protected with extreme care Confidentiality is essential to psychiatric treatment The psychiatrist must be circumspect in the information he/she chooses to disclose to others about a patient |
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Term
What is required to breach doctor-patient confidentiality? |
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Definition
Written consent of the patient, though exceptions exist HIPAA was passed to protect information as the electronic age began to permeate medicine |
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Term
What is ensured by the Privacy Act of 1974? |
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Definition
Maintenance of privacy of all information that personally identifies an individual, both patients and employees Applies to written and verbal disclosure Patients and individuals acting on their behalf may request in writing to have access to and make corrections to their record Agencies have “Privacy Officer” or “Release of Information Officer” Some areas of information such as drug and alcohol abuse, HIV infection and sickle cell anemia have special protection |
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Term
What is the purpose of HIPAA? |
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Definition
Encourages efficiency and effectiveness of healthcare systems through development of electronic health information systems Creates standards to regulate electronic transmission, privacy and security of certain health information Requires training of individuals |
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Term
What is considered protected health information (PHI) under HIPAA? |
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Definition
Identifying information related to past, present or future mental or physical condition Services or treatment provided Payment information |
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Term
What are problems with confidentiality under HIPAA? |
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Definition
The risks of possibly breaching confidentiality in the interest of good care are often overstated The risks of not providing important patient information to clinicians, or of not obtaining important information from third parties, are usually greatly understated Clinical-entity-to-clinical-entity communication in a patient’s interest is almost always acceptable |
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Term
What are exceptions to confidentiality? |
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Definition
Medical emergencies Legal actions Insurance billing Protection of vulnerable persons, particularly children and the elderly Reportable infectious diseases: TB, HIV, syphilis, gonorrhea Potential victims of psychiatric patients – Tarasoff rule |
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Term
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Definition
A civil tort related to negligence of duty, either by omission or commission Applies to organizations as well as clinicians, and to organizations’ responsibility for their staff |
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Term
What are the 4 elements of malpractice? |
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Definition
Duty Breach of duty Damage Causation: the connection between the breach and the damage |
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Term
What must be shown in a malpractice suit? |
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Definition
Duty: arises from a special relationship with the damaged person, such as a doctor-patient, clinic-patient, or hospital-patient relationship Causation: usually the hardest element for the plaintiff to prove Damage: must be substantial |
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Term
What do you do if you or your organization get any communication from a lawyer about a patient, including a request for records? |
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Definition
Refer it immediately to your lawyer or insurance carrier Do not respond independently Do not ignore it |
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Term
Why are malpractice suits rare for psychiatrists? |
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Definition
Desire for confidentiality Less likely to be harmed Long-term relationships |
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Term
What are the most common reasons for malpractice suits against psychiatrists? |
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Definition
Suicide most common reason Failure to obtain informed consent Adverse effects from medications or ECT Abandonment Sexual relations with patients |
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Term
What are the basic principles involved in dealing with difficult patients? |
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Definition
Identify and honor patient’s strengths Provide structure, goals, boundaries, function of tx Reassess patient situation Recognize own limitations Get help Take care of your own stress management |
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Term
What are the principles of effective listening? |
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Definition
Focus on conversation Ignore distractions Don’t interrupt Control your own emotions Avoid hasty judgments Acknowledge patient’s (family’s) perspective |
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Term
What limits should be set with patients? |
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Definition
Define what is and is not appropriate behavior Define what will and will not be tolerated Treatment and care-giving should be valued |
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Term
What is the purpose of setting limits? |
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Definition
Block habitual and maladaptive behavior Allow for the emergence of newly learned behavior |
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Term
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Definition
Target maladaptive behavior requiring change Address consequences of continued inappropriate behavior Communicate limits with the entire team Be aware of content and tone of communications Encourage patient and family to participate in limits Effective limits should be few in number The complete team must support the limits once set Provide patient and family with opportunity to verbalize responses |
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Term
What are the dynamics of a professional patient-physician relationship? |
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Definition
Physician agrees to provide medical services to a patient for a fee Patient trusts physician to act in his/her best interest Only patient discloses very personal information Patients may be unaware of the need for professional boundaries; physician is responsible for maintaining boundaries and held accountable in their absence |
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Term
What are the dynamics of a social relationship? |
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Definition
Initiated for the purpose of friendship Mutual needs are met Communication includes giving advice and meeting basic needs such as lending money Both are responsible for maintaining the boundaries of the relationship |
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Term
What is the purpose of boundaries? |
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Definition
Limits that allow a patient and physician to connect safely in a therapeutic relationship based on the patient’s needs Protect client vulnerability Provide legal protection for physician |
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Term
What are typical areas where boundaries tend to be violated? |
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Definition
Self-disclosure Giving or receiving significant gifts Dual relationships Becoming friends Maintaining established conventions (providing treatment in social situation) Physical contact |
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Term
What are warning signs of sexual misconduct? |
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Definition
Gradual erosion of physician neutrality Perceiving patient as special Socializing outside of practice Self-disclosure Physical contact End of day or after hours appointments Free care Dating |
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Term
What is considered sexual misconduct? |
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Definition
“It is considered sexual misconduct for a physician to have sexual contact with any current patient whom the physician has interviewed and/or upon whom a medical or surgical procedure has been performed.” |
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Term
How should you approach treating an angry patient? |
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Definition
Acknowledge anger Accept the anger by listening Explore the reason for anger, even if you do not agree with it Reflect what he or she has been said Look for contributing factors, may not be obvious Reach an agreement if possible about what can be done to resolve the issue |
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Term
What are characteristics of dependent patients? |
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Definition
May be mildly or severely ill Have self perception of bottomless needs Perceive caregivers as inexhaustible This may result in weary avoidance of the patient |
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Term
What tactics are usually used by dependent patients? |
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Definition
Use flattery and unconscious seduction Extreme gratitude Feeling of specialness by caregiver |
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Term
What should be avoided when stamina exhausted with dependent patients? |
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Definition
A referral for psychiatric evaluation may be put forth in a way the patient perceives as rejection. Referrals in this context are destined to fail |
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Term
How should you manage a dependent patient? |
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Definition
Discuss with patient and families, patient is entitled to good care but there are limits to human knowledge, skill, stamina, and time Try to avoid saying “goodbye” Leave reminder of visits such as a card or note |
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Term
What are characteristics of entitled demanders? |
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Definition
Very needy Use intimidation, devaluation, and guilt-induction May be overtly hostile Patient is unaware of deep dependency underlying actions Hostility is born of the terror of abandonment Patient may be feeling weak, unattractive or unsuccessful |
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Term
How should you respond to entitled demands? |
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Definition
Re-channel entitlement "We can’t give you the good treatment you deserve unless you help. You’ll get the help you deserve if you stop mis-directing your anger at the people trying to help you. You need all the allies you can get" |
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Term
What type of comfort are entitled demanders seeking? How should you comfort them? |
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Definition
Feel more comfortable and secure if caregivers fulfill need for him to be acknowledged as a person of achievement Does not mean denying own medical expertise and skills |
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Term
How should you approach the treatment of an entitled demander? |
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Definition
May need to practice some defensive medicine Good charting Avoid debates Remain calm, gentle and firm Tireless repetition of the theme of acceptance that the patient deserves first-rate medical care |
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Term
What are characteristics of Manipulative Help-Rejecters? |
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Definition
Not seductive, grateful, or overtly hostile Appear to feel no regime of treatment will help May accept treatment, only to report again and again that it does not work Pessimism increases in proportion to caregiver’s efforts and enthusiasm When one symptom improves another appears in its place Symptoms and illnesses serve to maintain the relationship with the caregiver Patients frequently deny depression and refuse referral to psychiatry |
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Term
How do you deal with manipulation? |
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Definition
Put limits on unrealistic expectations Put limits on demanding hostility |
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Term
What are the characteristics of Self-Destructive Care-Refusers? |
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Definition
No self-destructive intent Tendency to prize independence Appeals to the patient’s sturdiness should be attached to the treatment plan Patient is using the defense of denial to survive Has given up hope of ever having needs met |
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Term
How should you approach the treatment of elf-Destructive Care-Refusers? |
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Definition
Patients respond to medical advice delivered with a lighthearted touch and focused on maintenance of good health Doomsaying, authoritarian approaches typically fail Patient easily denies bad news |
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Term
How do you provide optimal care to Self-Destructive Care-Refusers? |
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Definition
Psychiatry consult to see if depression exists and/or to evaluate competence Recognize limits such patients pose for even ideal caregivers Work with diligence and compassion to preserve the refuser as long as possible, just as one does with any other patient with a terminal illness |
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Term
What are the characteristics of a compulsive patient? |
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Definition
Presents with excellent self-discipline When stressed, reacts by needing as much information as possible as the preferred way of handling anxiety Striving for intellectual control Tends to master aggression and satisfy his conscience by hard work Copes with danger by increasing his efforts to be responsible and orderly -May seem inflexible and opinionated -May be hesitant, doubting and indecisive Tends to suppress emotions |
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Term
How should you approach a compulsive patient? |
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Definition
Responds to scientific medical approach Values sympathetic efficiency and cleanliness Physician should welcome patients active participation in decisions Recognize patient’s reasoning and high standards Encourage patient participation in care |
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Term
What are the characteristics of an aloof patient? |
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Definition
Lack of involvement with everyday events and concerns of people Quiet, seclusive, unsociable History of solitary interests and noncompetitive jobs Often oversensitive, fragile and lacking resilience Aloofness may be protective in avoiding painful experience Seeks solace and satisfaction within himself |
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Term
How should you approach an aloof patient? |
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Definition
Make few demands for personal involvement with others, but do not permit complete withdrawal |
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Term
What are characteristics of a Long-Suffering, Self-Sacrificing Patient or Family Member? |
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Definition
History of repeated suffering, rather from repeated illnesses or disappointments Inclined to disregard own comfort and be of service to other people Tendency to display suffering in exhibitionistic way despite overt humility Striving for love, care and acceptance, but feels too guilty and anxious to accept without self-sacrifice and suffering |
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Term
How should you approach a a Long-Suffering, Self-Sacrificing Patient or Family Member? |
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Definition
Express appreciation of the difficulties of illness as they are experienced by the patient Patients respond better when considering the burden that treatment will carry rather than the relief that health would bring May have to present recovery as a special additional task for the benefit of others |
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Term
How do you deal with patients experiencing feelings of aversion? |
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Definition
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Term
How do you deal with patients experiencing an impulse to counterattack? |
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Definition
Re-channel entitlement into expectation of good medical care |
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Term
How do you deal with patients experiencing feelings of depression who reject help? |
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Definition
Accept pessimism so patient does not feel abandoned |
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Term
How do you deal with patients experiencing feelings of wishing death? |
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Definition
Consider possibility that patients wishes to die Uncomfortable feelings not addressed make it more likely that errors in diagnosis and treatment will occur |
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