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Blood
Blood
22
Histology
Graduate
11/27/2012

Additional Histology Flashcards

 


 

Cards

Term
Primordial phase
Definition
-begins @ 2wks
-nucleated RBC with fetalhemoglobin
Term
Hepatosplenothymic phase
Definition
-2 months
-anucleated RBC and white BC production
Term
Medullolymphatic phase
Definition
-birth to rest of life
Term
Colony Forming Unit (CFU)
Definition
-stem cells under the capsule of the spleen
-pluripotent
-myloid or lymphoid
Term
Stem cell factor (Steel)
Definition
-regulates blood production
-stimulates all stem cells
-produced by stromal cells (in marrow)
-integral membrane protein
Term
Interleukins 1, 3, & 6
Definition
-regulates blood production
-stimulates many stem cells
Term
GM-CSF
Definition
-regulates blood production
-stimulates unipolar stem cells to produce Granulocytes and macrophages
Term
M-CSF
Definition
-regulates blood production
-stimulates unipolar stem cells to produce macrophages
Term
G-CSF
Definition
-regulates blood production
-stimulates unipolar stem cells to produce Granulocytes
Term
Erythropoietin
Definition
-Regulates blood production
-stimulates RBC production
-produced by kidney
Term
megakaryocytes
Definition
produces platelets (thromobopoiesis)
Term
spectrin
Definition
protein on RBC
forms concave shape
Term
Rouleaux Formations
Definition
string of red blood cells bound together
caused by proteins such as Fibrinogen
Term
C-Reactive Protein (CRP)
Definition
-production (by hemocytes) induced by macrophages in response to bacterial infection
-binds to bacterial so neutrophils can eat them
Term
Neutrophil circulation and lifespan
Definition
-circulation: 6-8 hr
-lifespan: 2-4 days
Term
Neutrophil function
Definition
phagocytose bacteria
Term
Erythrocyte Sedimentation Rate (ESR)
Definition
aggregation rate of RBC
-will go up in infection
Term
Eosinophils function
Definition
allergic reactions and parasitic
infections. Regulate other leukocytes
Term
Eosinophils circulation and lifespan
Definition
-circulation: 3-4 days
-lifespan: 8-12 days
Term
Basophil function
Definition
activated by antibody binding to Fc receptors to secrete
cytokines that influence other leukocytes
Term
Monocytes life span
Definition
1-4 days
Term
Platelet lifespan
Definition
7-10 days
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