Term
| Define hematocrit. What is its normal value? |
|
Definition
Hematocrit- percent volume of blood that is red blood cells
45% |
|
|
Term
Rank the following proteins in order of highest to lowest % in plasma. Describe their major function.
Globulins,Fibrinogen, Albumin |
|
Definition
Albumin (4.5%)>Globulins (2.5%)> Fibrinogen (0.3%)
Albumin- osmotic pressure of blood
Globulins- defense and transport
Fibrinogen- clot formation |
|
|
Term
All of the following are true about hemoglobin except:
A. Permits RBCs to carry O2 efficiently
B. Composed of 5 Globins(polypeptide chain) chains each linked to a silver group
C. Facilitates the transport of CO2 in blood as HCO3(Bicarbonate) |
|
Definition
| B. Hemoglobin is composed of 4 globins each connected to a heme(iron) group |
|
|
Term
| In sickle cell disease, RBCs assume a sickle shape after the abnormal hemoglobin is deoxygenated. They have shortened life spans and increase blood viscosity b/c they undergo polymerization. Describe the mutation that causes this disease. |
|
Definition
| Point mutation where one amino acid, valine, is substituted for another, glutamic acid, during the synthesis of the beta-globin chain. |
|
|
Term
Spectrin and Ankyrin anchor the latticework of cytoskeleton to the cell membrane of what cell?
A. Erythrocyte
B. Leukocyte
C. Thrombocyte |
|
Definition
|
|
Term
Which of the following contains azurephilic granules and specific color lacking granules containing alkaline phosphatase and antibacterial substances?
A. Basophils
B. Lymphocytes
C. Neutrophils
D. Eosinophils |
|
Definition
|
|
Term
Barr bodies are located on which of the following?
A. Eosinophil
B. Basophil
C. Neutrophil
D. Lymphocyte
E. B and C |
|
Definition
|
|
Term
Which of the following contains large, refractile granules that show a crystalline core containing "major basic protein" along with acid phosphatase and phospholipase?
A. Eosinophil
B. Basophil
C. Neutrophil
D. Lymphocyte
E. Monocyte |
|
Definition
|
|
