Term
How many liters of blood exist in the vascular compartment? |
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Definition
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Name some examples of the vascular compartment. |
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Definition
arteries, veins, hepatic sinusoids, dural sinuses, etc. All places you would normally have blood |
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Blood is made of what two parts? |
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Definition
plasma and formed elements |
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What are the formed elements? |
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Definition
erythrocytes, leukocytes, and platelets (thrombocytes) |
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Term
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Definition
the percentage of RBCs in whole blood |
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Term
What is a normal hematocrit? |
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Definition
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Plasma is made mostly of? |
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Definition
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What is the most abundant SOLUTE in plasma? |
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Definition
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What are the smallest plasma proteins? |
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Definition
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The role of albumens is to... |
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Definition
maintain proper osmotic balance between blood and interstitial fluid |
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Term
Albumens are synthesized.. |
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Definition
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Term
Alpha and Beta globulins have the same fx. what is it? |
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Definition
lipid transport in the blood |
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Term
Where are alpha and beta globulins synthesized? |
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Definition
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Gamma globulins are aka.. |
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Definition
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Term
Where are gamma globulins made? |
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Definition
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Term
What is an example of clotting factors? |
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Definition
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Term
Last stage of blood clotting involves turning _____ into _____. |
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Definition
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Term
What are some plasma nutrients found in plasma? |
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Definition
glucose, free amino acids, free fatty acids, lipoproteins, etc. |
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Term
Nitrogenous compounds found in plasma are.. |
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Definition
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Electrolytes found in plasma are.. |
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Definition
Na+, Cl-, Ca++, K+, Mg+, HCO3-, etc. |
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Term
Blood work looks at electrolytes levels to check the fx of what organ? |
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Definition
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Term
What are the smallest cells in the body? |
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Definition
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Definition
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Definition
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Term
Where does erythropoesis occur in a fetus? |
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Definition
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Term
Where does erythropoesis occur in an adult? |
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Definition
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Term
Pathway of erythropoesis: |
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Definition
Stem cells - erythroblasts - reticulocytes - blood stream - 1-3 days - erythrocytes! |
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Term
What is the cell called when it leaves the red marrow before it becomes an RBC |
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Definition
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Term
What controls the rate of erythropoesis? |
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Definition
Negative feedback mechanism involving hormone erythropoitein |
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Term
Where is erythropoietin made? |
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Definition
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Term
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Definition
defend against microorganisms |
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Term
What are the 5 types of leukocytes? |
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Definition
neutrophils, basophils, eosinophils, monocytes, lymphocytes |
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Term
What are the most abundant WBCs in normal blood? |
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Definition
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Term
Which are the first WBCs to arrive to an injury and the first to die? |
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Definition
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Term
Which WBC is your best defense again helminth infections? |
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Definition
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What is the rarest of the WBCs? |
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Definition
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Term
Which WBCs are involed in inflamation? |
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Definition
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These WBCs are the largest cells found in blood... |
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Definition
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Term
When these WBCs gets to an infection, they leave the blood into tissues and convert to macrophages.. |
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Definition
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Term
Which WBCs are the smallest? |
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Definition
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Term
Which cells make antibodies? |
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Definition
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Term
When a tissue is injured what chemicals are released at the site? |
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Definition
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Term
Paracrine chemicals cause what to happen? |
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Definition
vasodilation of arterioles, and increase permeability (vaso D, increase P), increase blood flow to area |
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Term
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Definition
when neutrophils move toward vessel and gets tumbled over to the wall |
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Term
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Definition
WBCs attatching themselves to the vessel walls |
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Term
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Definition
When the WBC crawls out of the blood vessel into the tissue space and will move toward the source of paracrines |
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Term
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Definition
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Term
What are the 3 stages of hemostasis? |
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Definition
vascular spasm, platelet plug, clot formation |
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Term
What is the inner lining of a blood cell? |
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Definition
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Term
Describe a vascular spasm |
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Definition
a reflex vasoconstriction at the cut site, 30 min, platelets encounter collagen and develop sticky threads |
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Term
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Definition
does not stop the bleeding, platelets release serotonin thus prolonging vasoconstriction |
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Term
Describe clot formation briefly |
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Definition
fibrinogen combines to form fibrin |
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Term
What is the primary thing needed for clot formation |
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Definition
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Term
Thrombin is present in the blood as... |
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Definition
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The most important aspect of forming prothrombin is the activation of... |
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Definition
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Definition
Damaged tissues aroung the vessel make Tissue Thromboplastin (tissue factor) |
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Term
Intrinsic mechanism starts with .. |
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Definition
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Term
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Definition
this occurs as soon as the clot is formed, fibrin threads begin to shrink, broken edges of vessels draw together and healing occurs. Serum leaves the clot |
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Term
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Definition
plasma minus the clotting factors |
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Term
What do fibroblasts do when they invade a clot? |
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Definition
produce collagen to strengthen it |
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Term
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Definition
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Term
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Definition
Tissues form TPA (tissue plasminogen activator) which converts plasminogen to plasmin. Plasmin dissolves fibrin and therefore the clot |
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Term
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Definition
an abnl blood blot attached to a vessel wall |
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Term
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Definition
a free floating clot - a thrombus that breaks loose |
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Term
____ prevents clots and is most abundant in the lungs and liver |
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Definition
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