Term
|
Definition
| INTIMA changes in medium/large arteries |
|
|
Term
|
Definition
Raised lesion of lipid
Fibrous cap
Collagen deposition (stains blue)
Deposited in intima |
|
|
Term
|
Definition
| Weakened vessel wall --> Balloons out |
|
|
Term
| Atherosclerosis risk (HHCDCI) |
|
Definition
Hyperlipidemia
HT
Cigarettes
Diabetes
CRP/Inflammation |
|
|
Term
| Atherosclerosis pathogenesis (6) |
|
Definition
Lipoproteins (LDL) accumulation
Monocyte adhesion
Platelet adhesion
Factor release
Smooth muscle proliferation
ECM production |
|
|
Term
| Most common site of atherosclerotic aneurysm |
|
Definition
| Between lower abdominal aorta and upper iliac arteries |
|
|
Term
| Thoracic atherosclerosis location |
|
Definition
| Primarily dorsal by intercostal arteries |
|
|
Term
MC in thoracic/ascending aorta
Aortic valve dilated
Saccular outpouching (not all the way around)
Wrinkled tree bark intima |
|
Definition
| Tertiary/Syphilis aneurysm |
|
|
Term
|
Definition
Intimal tear in thoracic vessel
Blood --> media
1. Massive hemorrhage
2. Hemothorax
3. Pericardium rupture
4. Cardiac tamponade |
|
|
Term
MC in ACA
Congenital defect in media
Subarachnoid hemorrhage
Common in polycystic kidney disease pts. |
|
Definition
| Congenital/Berry aneurysm |
|
|
Term
| Classic fusiform aneurysm (2) |
|
Definition
Atherosclerotic abdominal aorta
Arteriosclerotic kidney --> HT |
|
|
Term
| Aortic dissection (adults) (2) |
|
Definition
|
|
Term
| Aortic dissection (younger) (3) |
|
Definition
RARE
CT abnormality
Marfan's
Cystic medial degeneration |
|
|
Term
| 95% have cANCA = Antineutrophil cytoplasmic Ab |
|
Definition
|
|
Term
|
Definition
Immune complex Noninfectious vasculutis
SLE |
|
|
Term
| Wegener's Granulomatosis (3Ns) |
|
Definition
Necrotizing granulomas of upper/lower respiratory tract
Necrotizing glomerulonephritis (hematuria) |
|
|
Term
> 50 yrs
In small arteries
Headaches/face pain
Optical symptoms |
|
Definition
MC vasculitis
Giant cell (Temporal) Arteritis |
|
|
Term
| Giant cell (Temporal) Arteritis Pathology (6) |
|
Definition
Lymphocytes and multinucleated giant cells
Nodular intimal thickening
Granulomatous inflammation of inner media
Fragmentation of internal elastic lamina
Lumen stenosis and thrombosis |
|
|
Term
Weak pulse in upper extremities (Classic Sign)
Ocular defects
F < 40 yrs |
|
Definition
Vasculitis of aortic arch great arteries
Takayasu Arteritis |
|
|
Term
| Takayasu Arteritis Pathology (7) |
|
Definition
Collagenous scarring of arterial wall
Thickened intima
Lumen stenosis
Granulamatous inflammation
Giant cells/monocyte inflammation of media
Patchy medial necrosis
Adventitial inflammation |
|
|
Term
Systemic S to M arteries
Capillaries spared
Episodic
Hep B Ag present in 30% (UNIQUE) |
|
Definition
|
|
Term
| Polyarteritis Nodosa Pathology (3) |
|
Definition
Transmural inflammation (Acute)
Fibrous nodular thickening (Chronic)
Impaired perfusion -> infarcts |
|
|
Term
| Kawasaki Disease General (4) |
|
Definition
NI Vasculitis of M to L arteries
Transmural inflammation
Fibrinoid necrosis less than PaN
Coronary arteries aneurysms (20%) --> Aneurysms, MI |
|
|
Term
| Hypersensitivity Leukocytoclastic Vasculitis (4) |
|
Definition
Immunologic reaction to Ag
Fragmented neutrophils in capillaries
Same aged lesions
Palpable purpura on legs |
|
|
Term
| Hypersensitivity Leukocytoclastic Vasculitis (2 Organs) |
|
Definition
Lung --> hemoptysis (coughing up blood)
Kidney --> hematuria |
|
|
Term
| Kawasaki Disease Kids (4) |
|
Definition
80% pts < 4 yrs
Leading cause of acquired heart disease in children
Cervical lymphadenopathy
Edema and rash |
|
|
Term
| Churg-Strauss Syndrome (2) |
|
Definition
Bronchial Asthma
Allergic rhinitis |
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
Smoking < 35
Feet ulcers (Tibial/Radial vasculitis)
Cold sensitivity (Raynauds) |
|
Definition
Thromboangitis Obliterans
Buerger Disease |
|
|
Term
| Endothelial cells targeted --> hemorrhage |
|
Definition
|
|
Term
| Angioinvasive arteritis in lungs |
|
Definition
|
|
Term
| Dilated tortuous superficial varicose veins (3) |
|
Definition
Increased intraluminal pressure
Incompetent valves
Noncontributory to pulmonary thromboemboli |
|
|
Term
Statis Dermatitis
Ulcerated Skin |
|
Definition
|
|
Term
|
Definition
Pain on foot dorsoflexion
DVT |
|
|
Term
| Adenocarcinoma (pancreas/colon) |
|
Definition
| Troussaeu = migratory thrombophlebitis |
|
|
Term
| Contributory to pulmonary thromboemboli |
|
Definition
|
|
Term
|
Definition
Benign
Increased number of blood vessels |
|
|
Term
Vascular tumor in skin and lips
Most common hemangioma |
|
Definition
|
|
Term
| Vascular tumor in deep tissue, large dilates vessels |
|
Definition
|
|
Term
Benign smooth muscle cell tumor
Painful
Digits |
|
Definition
|
|
Term
Reddish purple raised patches
Spindle cells
Slit spaces |
|
Definition
|
|
Term
| Kaposi Sarcoma types (BETH) |
|
Definition
Bantu children
E. European men lower legs
Transplant Associated
HIV |
|
|
Term
Malignant anaplastic endothelial cell neoplasm
Increased N/C ratio |
|
Definition
|
|
Term
| Hepatic Angiosarcoma causes (CPcAT) |
|
Definition
Carcinogens
Polyvinyl chloride
Arsenic
Thorotrast |
|
|
