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Composed of RBCs, plasma, WBCs, and platelets. The vol of ea Unit is approx. 500mL and consists of 200mL of RBCs and 300mL of platelets, with a min hemoglobin level of 38% |
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1 Unit of whole blood effect on Hgb and Hct |
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In an adult, 1 U of whole blood increases the hemoglobin by about 1 g/dL or the Hct by 3-4% |
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In a normal adult pt, 1 U of RBCs should raise the Hgb level by approx. 1 g/dL and the Hct by 3% |
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M= 13-18 g/dL F= 12-16 g/dL we want at least 11 g/dL critical level= <5 g/dL or >20 g/dL |
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M= 45-52% F= 37-48% we want at least 33% critical levels= <15% or >60% |
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Respiratory pigment of RBCs ie carries oxygen to your cells. It is a protein that is carried by red cells. It picks up oxygen in the lungs and delivers it to the peripheral tissues to maintain the viability of cells. |
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The proportion of the blood that consists of packed red blood cells. The hematocrit is expressed as a percentage by volume. The red cells are packed by centrifugation. |
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An immune response generated in an individual or strain of one species by an alloantigen from a different individual or strain of the same species. |
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Removal of only necessary blood components and return of unused portion. EX removal of plasma is plasm pheresis. |
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Graft-vs-Host Dz (pg 631) |
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When an immunocompromised recipient reacts to one of the donor HLA cells...The T lymphocytes become activated, engraft & proliferate...attack on the host cell tissues begins. This is fatal. Prevented by irradiating donor unit prior to infusion. |
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150,000-450,000/mm3 critical levels= <50,000 and >999,000/mm3 |
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HLA-Human Leukocyte Antigen is... |
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