Term
|
Definition
ACE Inhibitors
Captopril, enalapril, fosinopril, lisinopril, perindopril, quinapril, ramipril, trandolapril.
Block renin-angiotensin-aldosterone mechanism |
|
|
Term
| Angiotensin II receptor antagonists |
|
Definition
Angiotensin II receptor antagonists
Candesarten, eprosarten, irbesarten, losarten.
"Antagonists of the angiotensin AT-1 receptor
* Decrease peripheral vascular resistance
* Inhibit aldosterone release" |
|
|
Term
| α1‐Adrenoceptor antagonists |
|
Definition
α1‐Adrenoceptor antagonists
Prazosin, doxazosin, terazosin
"Block alpha receptors on arterioles and venules p
Inhibit sympathetic nervous system-mediated vasoconstriction and thereby reduces peripheral vascular resistance
Used in severe hypertensive crisis" |
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Term
|
Definition
Beta Blockers
Propranolol, oxprenolol, atenolol, metoprolol.
"Act by blocking β1 adrenergic receptors - Reduces cardiac output by decreasing heart rate and
myocardial contractility" |
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|
Term
| Calcium channel antagonists |
|
Definition
Calcium channel antagonists
Nifedipine, Amlodipine, Verapamil.
"Inhibit calcium ion channels and block entry of calcium
into vascular smooth muscle and myocardial cells
* Produces peripheral vasodilatation and also reduces
the force of myocardial contraction" |
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|
Term
|
Definition
Hydrochlorothiazide.
Diuretics
"Decreases blood pressure by
reducing blood volume
By acting on the kidneys to
increase urine flow" |
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