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blood part f
blood part f
17
Anatomy
Undergraduate 1
11/05/2008

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Term
What do the etrinsic and intrinsic release?
Definition
Thromboplastin
Term
Which has less steps, extrinsic or intrinsic release of thromboplastin?
Definition
Extrinsic
Term
In the formation of the platelet plug, what is digestion?
Definition
Done by phagolysosome
Term
In the formation of platelet plug, what is phagocytosis?
Definition
Done by pseudopods moving in the vesicle with pseudopods
Term
In the formation of platelit ring, what is roling?
Definition
Neutrophils and monoctes bind to selectins (adhesion molecules)
Term
What is another term for adhesion molecules?
Definition
Selectins
Term
What is Margination?
Definition
In the formation of platelet plug, margination is more binding of adhesion molecules at damaged site causing these cells to flatten through blood vessel wall
Term
What is Diapedesis-transmigration?
Definition
In the formation of a blood platelet plug, this involves neutrophils and monocytes squeezing through blood vessel wall transmigration or immigration
Term
What are chemicals called that are released by platelets
Definition
Chemotaxis
Term
What are the stages monocytes and neutrophils go through for formation of platelet plug?
Definition
Rolling, Margination, Diapedesis, Opsonization, Phagocytosis, Digestion
(rolling much dirt, oops poopy doo doo)
Term
What happens with intrinsic release of thromboplastin?
Definition
Large amounts of thromboplastin released tdue to collagen -platelet interaction
Term
What happens in extrinsic release of thromboplastin?
Definition
Small amounts of thromboplastin released by damaged tissues= NO Platelet involvement
Term
In Blood Clotting, what are the stages?
Definition
Thromboplastin-cascade-formation of prothrombin activator. Prothrombin and prothrombinase forms Thrombin.
Thrombin and Calcium form fibrinogen and that in terms form fibrin and insoluble clot
Term
What is clot dissolution called?
Definition
Fibrinolysis
Term
What is clot retraction called?
Definition
Synersis
Term
What are the steps of clot retraction?
Definition
Plasminogen binds to endothelium. tPa released from cells with fibrin clot (controlled activation) that converts plasminogin to plasmin. Plasmin dissolves clot, cleaves fibrin, from edges of wound in clot retraction
Term
What is tPa?
Definition
Tissue plasminogen activator
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