Term
| What is the difference between plasma and serum? |
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Definition
| Plasma is the liquid of centrifuged blood. Serum is plasma minus the clotting factors. |
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Term
| What are the four criteria for recognizing and distinguishing WBCs? |
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Definition
a) morphology of nuclei
b)presence/ absence of granules and their color
c) size of cell
d) relative abundance |
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Term
| Name the granulocyte WBCs |
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Definition
| Neutrophils, Eosinophils and Basophils |
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Term
| Name the agranulocyte WBCs |
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Definition
| Lymphocytes and Monocytes |
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Term
| What is the most abundant WBC? |
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Definition
| the Neutrophils (60-70% of all WBCs) |
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Term
| Which is the largest WBC? |
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Definition
| Monocytes are the largest |
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Term
| Which WBC is responsible for phagocytosis? |
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Definition
| Neutrophils. They are capable of creating reactive oxygen species (O2, H2O2 and HOCl) to help in that process |
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Term
| Which WBC is chemotactic to parasites? |
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Definition
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Term
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Definition
| Hemopoiesis is the formation of blood cells (from stem cells) |
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Term
| What color bone marrow do adults have? |
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Definition
| Adults have yellow bone marrow, which has low RBC production. Infants have red marrow, which makes lots of RBC. In times of need, adults may switch to red marrow. |
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Term
| There are six stages in the erythropoietic series (proerythroblast -> erythrocyte). What is the best way to distinguis between the different phases? |
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Definition
| Size. Erythrocytes are the smallest. Only reticulocytes and erythrocytes are anucleated. |
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Term
| Platelets (aka __________) are disk shaped cell fragments of much larger ____________. |
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Definition
1) thrombocytes
2) megakaryocytes |
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Term
| List four major features of RBCs |
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Definition
1) no nucleus
2)durable
3) deformable (can compress)
4)elastic (can return to original shape) |
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Term
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Definition
| Anemia is a decreased functional capacity of blood to deliver O2 to tissues/cells |
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Term
| Anemia may be caused by a decrease in numbers of RBCs. What can cause a decrease in RBCs? |
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Definition
RBC decrease can be caused by:
a) blood loss
b)hemolytic anemia (abnormal breakdown of RBCs)
c) ineffective erythropoieses (new RBC formation) |
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Term
| Anemia may be caused by an insufficient amount of functional hemoglobin. What causes dysfunctional Hb? |
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Definition
a) hemoglobinopathies
b) defect in heme synthesis
c) iron deficiencies |
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Term
| _______________ is an anemia associated with erythrocytes of reduced size and hemoglobin content. |
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Definition
| Microcytic hypochromic anemia |
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Term
| __________ is an anemia caused by low numbers of large RBCs. |
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Definition
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Term
| In a CBC, the ______________ gives the volume of red blood cells/volume of blood. |
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Definition
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