Term
| BLOOD GROUPS AND TRANSFUSIONS |
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Definition
| Early attempts to transfer blood from one person to another produced varied results. Sometimes the recipient improved. Other time the recipeint suffererd a blood reaction in which the red blood cells clumped, obstructing vessels and producing great pain and organ damage. |
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Term
| BLOOD GROUPS AND TRANSFUSIONS COUNTINUED |
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Definition
Eventually scientist determined blood is of different types
Only certain combinations of blood types are compatible |
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Term
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Definition
Aggulatination-clumbing of RBC's, following a transfusion reaction. Due to reaction between:
-Red blood cells surface molecules: antigens
-Proteins: Antibodies
-Anxiety, Breathing difficulty, facial flushing, headache, severe pains
-Avoiding the mixture of certain kinds of antigens and antibodies prevents adverse transfusion reactions |
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Term
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Definition
-Based on: presence of two major antigens on red blood cell membranes. -Antigen A and -Antigen B
RBC's have one of 4 antigen combinations on their membrane
-Based on inheritance only A, only B, Both A and B, or Neither A or B
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Term
| ABO BLOOD GROUP COUNTINUED |
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Definition
Only antigen A has type A blood. Only Antigen B has type B blood. Both antigen A and B is type AB blood. Neither antigen A nor B has type O blood.
In the US, the most common ABO blood types are O (47%) and A (41%). AB is 3%. |
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Term
| Antibodies are synthesized about 2-8 months following birth |
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Definition
-Persons with type A blood have antibody anti-B
-Persons with type B blood have antibody anti-A
-Those with type AB blood have neither antibody
-Tose with type O have both antibody anti-A and antibody anti-B |
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