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surface layer. stratified squamous epithelium. keratinized in superficial strata and varies in thickness among different regions of the body. |
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middle layer. supports epidermis via blood vessels, nerves, and epidermal appendages |
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composed primarily of adipose tissue and loosely attaches skin to underlying structures |
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predominate cell. waterproofs skin. |
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spider shaped cells of deeper epidermis that synthesize pigment. incorporated into keratinocytes to protect underlying structures from UV. appear as round cells with pale staining cytoplasm. |
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macrophages. most easily seen in stratum spinosum. |
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separated from dermis by basement membrane. layer closest to blood supply. keratinocytes exist as single layer of columnar cells. high mitotic activity. |
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8-10 cells in this layer. slight mitotic activity, particularly in deeper layers, superficial cells too far removed from blood supply. |
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3-5 cels thick. keratinization begins here. granular appearance due to ribosomes. upper cells of this layer begin to die and flatten out to eventually obtain squamous shape. |
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clear layer. only present in thick skin (palms, solves and regions of friction) |
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most superficial layer thickness varies greatly between thick and thin. dead cells filled with keratin, superficial cells constantly being shed. |
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composed of loose and dense irregular connective tissue. mainly fibroblasts with occasional macP, lymphocytes, mast cells and other immune cells. rich nerve, lymph, blood supply. |
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paler staining due to fewer fibers and more ground substance. rich in capillaries and nerve endings. |
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darker staining due to abundance of large diamter collagen and elastic fibers, provides strength and elasticity. adversely affected by UV light. |
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elongated columns of fused keratinized epithelial cells originating from a tubular evagination of the epidermis into the dermis. growth occurs from bulb and base of follicle. contains layers of both dermal and epidermal origin. |
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simple cuboidal epithelium arranged in coiled simple tubular glands. secrete via action of myoepithelial cells. secretory portions in deep dermis and sometimes hypodermis. |
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cover most of the body but most concentrated in regions of thick skin. thermoregulation. myoepithelial cells. duct serpentines to empty on skin surface. |
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ducts empty into hair follicles in axiallary and anogenital regions. secretions metabolized by microbes to make body odor. |
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simple or compound alveolor glands with a washed out appearance similar to adipose |
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