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Block 6 - Bacteria
Buzz words
55
Bartending
Pre-School
09/22/2009

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Term
G+, cocci, grape cluster, catalase+, coag+, slimy capsule, skin ABCESS IS HALLMARK, ACUTE ENDOCARDITIS, PNEUMONIA AFTER VIRAL INFECTION, PREFORMED ENTEROTOXIN IN FOOD POISONING, TSST-1 superantigen, exfoliative exotoxin A/B SSSS in kids, immune evasion by protein A binding to IgG-Fc and coagulase activate prothrombin, community acquired makes P-V toxin against PMN.
Definition
Staph aureus
Term
G+, cocci, catalase +, coagulase -, not virulent, polysaccharide slime, INFECTS PROSTHETIC DEVICES AND CATHEDERS, novobiocin sensitive.
Definition
Staph epidermis
Term
G+, cocci, catalase +, coagulase -, urease, not virulent, UTI, novobiocin resistant.
Definition
Staph. Saprophyticus
Term
G+, cocci, short chains, catalse -, b-hemolytic, bactitracin sensitive, ASO titer increase, M protein, capsule, lipoteichoic acid, PHARYNGITIS, SKIN INFECTIONS, SCARLET FEVER (RASH, BERRY TONGUE), TSS, RHEUMATIC FEVER FOLLOWING PHARYNGITIS, ACUTE GLOMERULAR NEPHRITIS, pyrogenic exotoxins A/B/C, Streptolysin S and O lyse RBC, Pr F attachment to fibronectin.
Definition
Strep pyogenes group A
Term
G+, cocci, catalase -, b-hemolytic, bacitracin resistant, group B cell wall anigen, thick cell wall, NEONATAL PNEUMONIA AND MENINGITIS.
Definition
Strep agalacticae group B
Term
G+, cocci, catalse -, pairs (lancet diplococci), capsule, a-hemolysis, optochin sensitive, teichoic acid, MOST IMPORTANT CAUSE OF CA-PNEUMONIA, MOST IMPORTANT CAUSE OF CA-MENINGITIS IN ADULTS, ALSO CAUSES OTITIS MEDIA/SINUSITIS, 23 valent vaccine for adults and IC, conjugate vaccine for babies.
Definition
Strep pneumo
Term
G+, cocci, catalase -, coag -, a-hemolytic, optochin resistant, cause tooth decay and damaged heart valves.
Definition
Viridans strep
Term
G+, cocci, pairs or short chains, NOSOCOMIAL INFECTIONS, UTI, ENDOCARDITIS, part of normal bowel flora.
Definition
Enterococcus
Term
G+, bacillus, anaerobic, spore-forming, Nagler rxn (lecithinase on egg yolk), causes GAS GANGRENE, CELLULTIS, FOOD POISONING, Alpha toxin lyses RBC, WBCs, Beta toxin causes necrotizing enteritis, enterotoxin.
Definition
Clostridium perfrigens
Term
G+, bacillus, anaerobic, terminal spores, tetanospasmin plasmid causes heat labile AB neurotoxin that is metalloprotease that prevents GABA release, CAUSES TENTANUS OR FATAL NEONATAL TENTANUS.
Definition
Clostridium tentani
Term
G+, bacillus, spores, anaerobic, botulism AB toxin limits Ach release, don’t give honey to babies <1 cause spores make toxin in vivo.
Definition
Clos botulinum
Term
G+, bacillus, spores, anaerobic, enterotoxin A, cytotoxin B, grows out after anti-biotic treatment, DIARRHEA, PSUEDOMEMBRANOUS COLITIS.
Definition
Clos difficile
Term
G+, pacillus, spores, capsule, 3 exotoxins, CUTANEOUS OR INHALED ANTHRAX.
Definition
Bacillus anthracis
Term
G+, bacillus, spores, preformed heat stabile toxin, QUICK FOOD POISONING 1-6 hours, from old rice or meat.
Definition
Bacillus cereus
Term
G+, rod, AB toxin, Diptheria toxin from bacteriophage inhibits protein synthesis via EF2, causes leathery psuedomembrane DIPTHERIA.
Definition
Corynebacterium diphtheria
Term
G+, rod, ENDOTOXIN LPS-LIPID A, motile with H-Ag, fac intracell, catalase +, b-hemo, NEONATAL OR REGULAR MENINGITIS, escapes phagosome via hemolysin and propels via ActA,.
Definition
Listeria mono
Term
G+, rod, filaments, yellow sulfur granules in infections, anaerobe, CAUSES GRANULOMAS WITH ABCESSES VIA SINUS TRACTS.
Definition
Actinomyces
Term
G+, branching rod, acid fast, infection with impaired CMI, can cause PNEUMONIA OR CUTANEOUS INFECTIONS, OR CAUSE MYCETOMA (FOOT INFECTION).
Definition
Nocardia
Term
G+, rod, acid fast, triggers TLR2/1 needs Vit D dependent immune response, cord factor results in parallel growth of organism, PRIMARY LUNG DISEASE OFTEN ASYMPTOMATIC WITH CASEOUS NECROSIS, SECONDARY IS REACTIVATION, MILIARY IS DISSEMINATED GRANULOMAS ALL OVER BODY, PPD/mantoux test is purified protein with Type 4 rxn, booster phenom- latent infection is false negative at first.
Definition
Myco tuberculosis
Term
G+, rod, acid fast, triggers TLR2/1 needs Vit D dependent immune response, ONE VERSION OF DISEASE ACTIVATES TH1(IL-2, IFN-Y) WITH MINIMAL SKIN DAMAGE AND ORGANIZED GRANULOMAS, OTHER VERSION IS TH2(IL-4,IL-10) WITH SKIN DAMAGE AND DISORGANIZED GRANULOMAS AND BACILLI, HLA-DR2/3 associated with organized version.
Definition
Myco leprae; lepromin test measures Type 4 rxn, Mitsuda measures CMI response like positive in tuberculoid
Term
G+, rod, acid-fast, intracellular, from fresh or ocean water, seen as DISSEMINATE IN AID PATIENTS, ALSO PULMONARY OR CUTANEOUS subtypes.
Definition
MAC, myco bovis, myco marinum
Term
g-, rod, lactose -, catalase+, oxidase -, H2S+, motile, Vi Ag for capsule, type 3 secretions via patho islands, invasive strains, can set up carrier state in gall bladder, causes BLOODY OR NON-BLOODY GE, ENTERIC FEVER, OR OSTEOMYELITIS IN SICKLE CELL PATIENTS.
Definition
Salmon typhi or paratyphi
Term
g-, rod, lactose -, catalase+, oxidase -, H2S+, motile, non-invasive, causes GE or OSTEOMYELITIS IN SICKLE CELL.
Definition
Salmonella typhimurium or enteriditis
Term
g-, rod, lactose-, catalase+, oxidase-, H2S-, non-motile, type 3 secretions for invasion, Shiga toxin inhibs 60S ribo in endothelial cells, spreads like listeria, CAUSES FEVER, DIARRHEA, BLOODY STOOLS.
Definition
Shigella
Term
g-, rod, lactose-, catalase+, oxidase-, trans via a flea, type 3 secretions of YOPS proteins that destroy macros, CAUSES PLAGUE AND BUBOS OR SUBTYPE ENTEROCOLITIS.
Definition
Yersinia pestis or enterocilitica
Term
g-, rod, lactose+, catalase+, oxidase-, growth on EMB or MC agar, 3 major antigens - O for outer LPS, K for kapsule, and H for flagella, plasmid AB toxin similar to cholera toxin (up cAMP), ST and LT toxins, CAUSES TRAVELERS WATERY DIARRHEA.
Definition
Enterotoxigenic e coli
Term
g-, rod, lactose+, catalase+, oxidase-, growth on EMB or MC agar, 3 major antigens - O for outer LPS, K for kapsule, and H for flagella, type 3 secretions with pedestals, CAUSE INFANT NON-BLOODY DIARRHEA.
Definition
Enteropathogenic e coli
Term
g-, rod, lactose+, catalase+, oxidase-, growth on EMB or MC agar, 3 major antigens - O for outer LPS, K for kapsule, and H for flagella, plasmid toxin similar to shiga, invasive like listeria, BLOODY STOOLS.
Definition
Enteroinvasive e coli
Term
g-, rod, lactose+, catalase+, oxidase-, growth on EMB or MC agar, 3 major antigens - O for outer LPS, K for kapsule, and H for flagella, phage shiga like toxin Stx-1, Stx-2 can cause hemolytic uremic, CAUSES BLOODY DIARRHEA.
Definition
Enterohemorrhagic e coli 0157
Term
g-, rod, lactose+, uric+, citrate+, orange mucoid colonies, alcoholics complicate, most common cause of CA PNEUMONIA.
Definition
Klebsiella pneumo
Term
g-, rod, lactose+, catalase+, oxidase-, growth on EMB or MC agar, 3 major antigens - O for outer LPS, K for kapsule, and H for flagella, P pili to climb kidneys, type 1 fimbria form facet cells in ureter, CAUSE UTI AND ALSO NEONATAL MENINGITIS.
Definition
UROPATHOGENIC e coli
Term
g-, rod, lactose-, catalase+, oxidase-, hundreds of pili, swarming on agar, UREASE, causing UTI and STRUVITE KIDNEY STONES.
Definition
Proteus mirabilis
Term
g-, rod, lactose+, catalase+, oxidase-, NOSOCOMIAL UTI, PNEUMO, MENINGITIS.
Definition
ENTEROBACTER (U-,C+) AND CITROBACTER
Term
g-, rod, lactose-, oxidase+, pyocyanin stims superoxide, grape odor, polysaccharide capsule makes biofilm, exotoxin A protein ihibs, exoenzymes S&T via type 3 secretion causes tissue invasion, protease/elastases and phospholipase C causes tissue destruction, CAUSES SKIN INFECTION IN BURNS, UTI, EXTERNAL OTITIS (SWIMMERS), MALIGNANT OTITIS IN DIABETICS, AND NECROTIC LESIONS CALLED ECTHYMA GANGRENOSUM.
Definition
P. Auerginosa
Term
g-, rod, anaerobic, capsule, no LPS activity, CAUSES FEVER IN POST-SURGICAL PERITONEAL ABSCESSES.
Definition
Bacteroides
Term
g-, rods, odontogenic, fastidious, fac anaerobes, CAUSE CULTURE NEG ENDOCARDIDTIS.
Definition
HACEK bugs; hemo, actinobaccilus, cardiobacterium, eikenllea, kingella
Term
g-, curved rod, single polar flagellum with phage AB toxin, non-invasive, crosses mucous membrane, attaches to SI via adhesions, AB enterotoxin ups cAMP, CAUSES RICE WATERY STOOLS OR WOUND INFECTION WITH BULLAE.
Definition
Vibrio cholera or vulnificus
Term
g-, curved rod, single polar flagellum, no carbs, MOST COMMON CAUSE OF BACTERIAL GE EITHER WATERY OR BLOODY, CAN CAUSE REACTIVE ARTHRITIS.
Definition
Campy
Term
g-, curved rod, single polar flagellum, CaG patho island, colonization increases with age, UREASE, VacA cytotoxin, O2 radicals can cause carcinoma, breath test with radioactive urea, CAUSES GE, ULCERS, OR GI CARCINOMA/LYMPHOMA.
Definition
Helicobacter
Term
g-, diplococcus, grows on chocolate agar, capsule, LPS, complement deficiencies increase risk, CAUSES MENINGITIS THAT CAN LEAD TO PETECHIAE AND DIC.
Definition
Neisseria menin
Term
g-, diplococci, no capsule, pili attach to membranes, seen in PMNs, chocolate agar, STD, CAUSES UTI, PID, OR DISSEMINATED DISEASE.
Definition
Neisseria gonorrhea
Term
g-, spiral, primary disease causes painless ulcer, secondary MUCOCUTANEOUS RASH, LATE CAUSES CHRONIC INFLAMM WITH ORGAN DESTRUCTION, NEURO, CARDIO, AND GUMMAS IN SKIN AND BONE, congenital causes rhinitis, hutchinon’s teeth, saddle nose, and frontal bossing, synergy with HIV.
Definition
Treponema pallidum; tested with non specific VDRL cardiolipin protein and specific FTA-ABS
Term
g-, spiral, antigenic variation of VSP, tick or louse vector, OspA releases bacteria from bug gut into saliva, CAUSES EITHER RELPASING FEVER, OR FLU-LIKE DISEASE WITH ERYTHEMA MIGRANS, early disease can disseminate while late can cause arthritis and dermatitis chronically.
Definition
Borrelia burgdorferi (tick) or recurrentis (louse)
Term
g-, spiral, one or two hooks on end, damages small endothelia vessels that may result in hemorrhage or renal failure, CAUSES ANICTERIC FLU-LIKE SYMPTOMS LEADING TO BACTEREMIA AND ICTERIC WEIL SYNDROME CAUSING LARGE AMOUNTS OF Ag, RENAL FAILURE, AND HEMORRHAGIC PNEUMONITIS.
Definition
Leptospira
Term
g-, rods, in kids CAUSES BENIGN LYMPHADENOPATHY CAT SCRATCH FEVER, OR “TRENCH FEVER” 5 DAY INTERVAL FEVER via body louse, or sandfly induced “ORROYA FEVER” CAUSING CHRONIC SKIN LESIONS AND ANEMIA.
Definition
Bartonella henselae, quitana, or bacilliformis
Term
g-, cocc-rod, encapsulated type b most virulent, non-encapsulated called non-typable, anti-PRP capsule, needs hemin and NAD, conjugate vaccine, TYPE B CAUSES PNEUMONIA AND PEDIATRIC MENINGITIS, NON-TYPABLE MOST COMMON CAUSE OF OTITIS MEDIA IN CHILDREN, OR STD CAUSE OF CHANCROID.
Definition
H. flu B, flu, paraflu, and ducreyi
Term
g-, rod, requires cysteine and iron for growth, intracellular, binds C3b receptors to enter macros phagosome, CAUSES PNEUMONIA IN ICs OR PONTIAC FEVER which is a self-limited fever without pneumonia.
Definition
Legionella pneumophila, micdadei
Term
g-, cocco-rod, AB toxin for Gprotein ups cAMP, adenylate cyclase toxin ups cAMP in leukocytes cause apop, tracheal toxin kills ciliated cells, adhesions, CAUSES PERSISTENT COLD-LIKE COUGH WITH CATARRHAL, PAROXYSMAL, AND CONVALESCENT STAGES which can lead to pneumo or menin.
Definition
Bordetlla pertussis; has acellular vaccine with pertussin toxin, FHA, pertactin, and Type 2/3 fimbriae
Term
g-, small, cocc-rod, lives in PMN spreads to reticuloendo, milk and animals, CAUSES UNDULANT FEVER WITH MALAISE AND CHILLS.
Definition
BRUCELLA
Term
g-, cocc-bac, capsule, found in rabbits, cats, ticks, phago-lysosome in macros, CAUSES GLANDULAR FEVER, WITH MALAISE, CHILLS, FATIGUE.
Definition
Francisella tularensis
Term
g-, small, cocc-rod, dog or cat bites, CAUSE STREAKY CELLULITIS THAT MAY INFECT JOINTS/BONES.
Definition
Pastruella multicoda
Term
no cell wall, sterols, smallest organism, p1 adhesin attaches to epithelial cells, they are superantigens, fried egg morphology on diagnosis, subtypes contracted sexually, CAUSES MILD URI OR ATYPICAL PNEUMONIA, SUBTYPES CAUSE NON-GONO URETHRITIS, OR PYELO, OR PID.
Definition
Mycoplasma pneumo, hominim, genitalum, and Ureaplasma (urethritis)
Term
g-, poor staining, obligate intracellular, free in cytoplasm of endothelial and RBCs, no toxins, via ticks or human body louse, indirect fluorescent antibody test, CAUSES ROCKY MOUNTAIN SPOTTED FEVER WITH TOTAL BODY RASH with acral skin AND VASCULAR DAMAGE, or TYPHUS WITH RASH AND VASCULITIS.
Definition
Rickettsia rickettsii, or typhi; epidemic typhus has rash while small percent of endemic do.
Term
g-, obligate intracellular, replicates in phagolysosomes, phase variation between acute and chronic, inhaled from farm animals, ACUTE FEBILE ATYPICAL PNEUMONIA OR CHRONIC HEPATITIS.
Definition
COXIELLA, called Q fever
Term
g-, elementary body is infectious spore, reticulate body has cell wall, obligate intracellular, lacks a true peptidoglycan layer, energy parasite, serology is MIF, culture is gold standard, common STD, CAUSES URETHRITIS, PROSTATIS IN MEN AND ASYMPTOMATIC BUT PID, ECTOPIC, OR INFERTILITY IN WOMEN, can cause trachoma involving in-turned eyelashes and conjunctivitis, 3rd world lymphogranuloma veneruem has genital lesion and bubo; subtypes CAUSE ATYPICAL PNEUMO OR SEVERE PARROT FEVER PNEUMO.
Definition
Chlamydia trachomatis, pneumo, and psittacci
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