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Block 5 Path Exam 1
Path Exam 1
71
Histology
Graduate
08/22/2012

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Cards

Term
oral cavity
Definition
most specialized reion of the tubular portion of the alimentary tract. lacks typical layering
Term
lining of the mouth
Definition
mucous membrane consisting of nonkeratinized stratified squamous (may be keritinized in regions of greater friction). submucosa contains many small salivary glands.
Term
lips
Definition
region of transition from keratinized to nonkeratinized stratified squamous epithelium. red margin
Term
vermilion
Definition
red region of dry epithelium. redness due to increased number and height of connective tissue papillae carrying an abundance of capillaries
Term
tongue
Definition
muscular organ used for tasting, gripping, manipulating food. speaking.
Term
taste buds
Definition
most prominent on the tongue but also found on soft palate, pharyngeal walls, and epiglottis. barrel shaped structures that extend through the epithelium from the basal lamina.
Term
taste pore
Definition
opening through which microvilli project from bud cells. nerve fibers wrapped around base.
Term
tongue muscles
Definition
fasciles all arranged in different planes and angles
Term
papillae
Definition
projections used to grip food
Term
filiform papillae
Definition
long, pointed projections. appear white due to keratinization. most numerous
Term
fungiform papillae
Definition
mushroom shapes with nonkeritinized epithelium. appear as small red dots. some contain taste buds.
Term
circumvallate papillae
Definition
broad, circular and surrounded by deep moats. walls of crypts contain numerous taste buds
Term
von Ebner's glands
Definition
serous glands that empty into the base of moat surrounding circumvillate papillae. dissolve food molecules to aid in sense of taste
Term
foliate papillae
Definition
leaf shaped projections that overlap like shingles on the lateral posterior portion of the tongue. endowed with taste buds and ducts of serous glands emerge between papillae.
Term
myoepithelial cells
Definition
cradle each acinus. contract to help propel secretory products.
Term
serous cells
Definition
demonstrate secretory granules that contain water, salts, enzymes and other proteins
Term
mucous cells
Definition
foamy appearance with flattened basal nuclei
Term
serous demilune
Definition
artifact of slide prep
Term
intercalated ducts
Definition
lined with simple squamous or a low cuboidal epithelium
Term
striated ducts
Definition
lined with simple columnar cells with reversed polarity that appear to have a striated basal border. pump ions from saliva into surrounding connective tissues. water follows via osmosis.
Term
interlobar ducts
Definition
formed by the junction of several intralobar ducts. begin as simple columnar epithelium eventually shifting to a stratified cuboidal/columnar.
Term
secretory ducts
Definition
lined by stratified cuboidal/columnar or pseudostratified epithelium which shifts to a stratified squamous just before empyting into the oral cavity
Term
parotid glands
Definition
largest. flattened pads in front of each ear. compound acinar glands containing only serous cells. produce salivary amylase. contain significant clusters of adipose (increases with age)
Term
submandibular glands
Definition
compound tubuloacinar seromucous glands located under middle third of body of mandible. produce bulk of saliva that enters oral cavity thru Whartons ducts. mixed serous and mucus.
Term
sublingual glands
Definition
series of compound tubuloacinar glands located under tongue. seromucous glands but mucous cells predominate.
Term
mucosa
Definition
lumenal lining. consists of 3 layers.
Term
epithelium
Definition
either nonkeritinized stratified squamous or simple columnar
Term
lamina propria
Definition
supporting loose irregular connective tissue. home to many immune cells.
Term
muscularis mucosa
Definition
thin layer of smooth muscle
Term
submucosa
Definition
relatively thick layer of loose connective tissue. rich in blood vessels.
Term
Meissner's plexus
Definition
network of nerves and small parasympathetic ganglia. between submucosa and circular muscle layer. controls secretion and absorption functions.
Term
muscularis externa
Definition
inner circular and outer longitudinal muscle layers
Term
sphincters
Definition
inner circular layer enlarged here. at junction of organs.
Term
Myenteric (Auerbach's) plexus
Definition
small ganglia located between muscle layers. controls motility.
Term
serosa
Definition
outermost layer of loose connective tissue when the tube is attached to a mesentery and surrounded by a simple squamous epithelium.
Term
adventitia
Definition
outermost layer composed of loose connective tissue when the outer layer blends in with the connective tissue of surrounding structures
Term
mucosa of esophagus
Definition
lined with stratified squamous epithelium. diffuse lymphoid tissue common within lamina propria. thick muscularis mucosa.
Term
submucosa of esophagus
Definition
contains mucous glands
Term
muscularis externa of esophagus
Definition
skeletal muscle upper 1/3, smooth muscle lower 2/3
Term
regions of stomach
Definition
cardia, body, fundus, pylorus
Term
stomach
Definition
liquefies food via chemical/enzymatic and mechanical digestion
Term
mucosa of stomach
Definition
lined by simple columnar epithelia arranged in glands
Term
mucus surface cells
Definition
common to all stomach regions as they line the surface between and within the lips of the gastric pits. different type of mucous than goblet cells. secrete via pinocytotic vesicles. appear foamy near apical surface. also make lysozyme. half life 3-5 days.
Term
lysozyme
Definition
secreted by surface mucus cells to destroy cell wall of gram positive bacteria
Term
undifferentiated reserve cell
Definition
found in gastric pits. can differentiate into several cell types as they migrate into proper position.
Term
mucous neck cells
Definition
produce chemically different type of mucous. smaller and stain darkly
Term
Parietal cells
Definition
eosinophilic (stain pink). pyramidal. upper portions of gastric glands. complex invaginations with microvilli. secrete HCl and intrinsic factor.
Term
chief cells
Definition
deeper portions of glands. basophilic cytoplasm (stain dark purple). secrete pepsinogen
Term
Enteroendocrine cells
Definition
small pyramidal. clear unstained cytoplasm. stain with silver or chromium salts. secrete products into lamina propria to enter capillaries.
Term
cardiac and pyloric glands
Definition
contain primarily mucus secreting cells
Term
gastric glands (fundus and body)
Definition
produce bulk of enzymes. short pits with compound glands.
Term
isthmus and neck portions
Definition
mucous neck cells and enteroendocriine cells
Term
base portion
Definition
predominantly chief cells with some parietal and scattered enteroendocrine cells
Term
lamina propria in stomach
Definition
occupies space between glands
Term
stomach muscle
Definition
has 3 layers: innermost oblique, middle circular, outer longitudinal
Term
submucosa of stomach
Definition
contains more mast cells and other lymph cells than other organs
Term
villi
Definition
small mucosa projections into lumen. only in small intestine. center is lamina propria
Term
absorptive cells of small intestine
Definition
most abundant. simple columnar with dense microvilli that form striated border.
Term
goblet cells of small intestine
Definition
become more abundant distally
Term
lamina propria of small intestine
Definition
forms core of each villus. capillaries and lacteals. richly infiltrated with lymphoid cells
Term
intestinal crypts of Lieberkuhn
Definition
simple, straight, tubular, glandular invaginations of the mucosa
Term
Panneth cell
Definition
grouped together in deepest parts of crypts. pink granules release lysozyme.
Term
plicae circularis
Definition
transverse folds in the submucosa
Term
duodenum
Definition
densely packed, long, broad, flat villi.
Term
Brunner's glands
Definition
submucosal glands that secrete sodium bicarbonate. aids in the neutralization of the HCl from the stomach
Term
jejunum
Definition
villi slight shorter and less closely packed.
Term
ileum
Definition
villi shorter, finger like. more widely dispersed. have peyer's patches
Term
Peyer's patches
Definition
lymphoid nodules embedded in diffuse lymphoid tissue. located in lamina propria on opposite side from mesentery.
Term
appendix
Definition
blind evagination of the cecum. contains absorptive, goblet, enteroendocrine, undifferentiated and Panneth cells. nodular lymphoid infiltration of lamina propria
Term
colon
Definition
deep crypts but no villi. absorptive, goblet and undifferentiated cells. goblet cells
Term
Rectoanal junction (line of Hilton)
Definition
mucosa shifts from simple columnar to stratified squamou
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