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Block 1: Unit 3
Quantal Theory & Analysis
9
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Undergraduate 4
09/20/2016

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Term
How were endplate potentials discovered?
Definition
recording electrode was put into muscle cell of frog NMJ & stimulated the nerve to fire an action potential
Term
How were miniature endplate potentials discovered?
Definition
kept recording from the muscle cell but without stimulating the axon
Term
toxins that block ACh receptors --> ?
Definition
block both EPPs & mEPPs --> death
Term
toxins that block acetylcholinesterase --> ?
Definition
bigger EPPs & mEPPs because ACh isn't getting broken down in the synapse
Term
Upon direct application of ACh to the muscle fiber, response varied depending on ______
Definition
how much ACh was applied
Term
Reducing calcium levels ______ the size of the EPPs & mEPPs
Definition
reduced
Term
2 results of small increases in calcium
Definition
1. frequency of mEPPs increases
2. size of EPPs increases
Term
3 factors that go into the response a muscle cell gives from a stimulus
Definition
1. n = number of vesicles ready to be released
2. p = probability of vesicle release
3. q = size of a single quantum
Term
equation for magnitude of EPPs
Definition
m = n(p)(q)
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