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biosystems
carbs lipids nucleotides
48
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Undergraduate 3
10/06/2011

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Term
carbohydrates
Definition
most abundant biomolecules
ch2o
Term
functions of carbs
Definition
-energy source
-structural elements (cellulose, chitin)
-cellular communication
-precursors in production of other biomolecules
Term
oligosaccharides
Definition
-3-10 monosaccharides
common in glycoproteins and glycolipids
Term
polysaccharides
Definition
-11 or more monosaccharides (polymers)
-not very soluble (ideal for energy storage)
Term
glycoconjugates
Definition
-protein and lipid molecules with covalently linked carbohydrate groups
-
Term
trioses
Definition
monosaccharide containing 3 carbon atoms
Term
tetroses
Definition
monosac containing 4 carbons
Term
pentoses
Definition
monosac containing 5 carbons
Term
hexoses
Definition
monosac containing 6 carbons
Term
monosaccharides
Definition
-have ketone or aldehyde functional group
-hydroxyl group on most or all non-carbonyl carbons
-most become cyclic in aqueous solution
Term
glucose
Definition
-aldose
-primary fuel for living cells
Term
fructose
Definition
-ketose
-referred to as fruit sugar
-twice as sweet as sucrose
Term
galactose
Definition
-aldose
-necessary for synthesis of various biomolecules
Term
galactosemia
Definition
-genetic disorder
-enzyme to metabolize galactose is missing
-galactose and derivatives accumulate causing liver damage, cataracts and retardation
Term
disaccharides
Definition
-bonded by a glycosidic linkage (1,4)
-too large to pass through cell membranes (therefore broken down by hydrolysis)
Term
sucrose
Definition
-table sugar
-disac of glucose and fructose
-synthesized only in plants
Term
maltose
Definition
-dimer of glucose
-released during hydrolysis of starch
-present in malt
Term
lactose
Definition
-galactose and glucose
-milk sugar
-synthesized in mammary glands
Term
lactase
Definition
enzyme required to hydrolyze the beta 1,4 linkage and digest lactose
Term
starch
Definition
-reservoir in plants
-2 polysaccharides (amylose and amlylopectin)
Term
amylose
Definition
-polysac of unbranched chains
-typically several thousand glucose residues
Term
amylopectin
Definition
branched polymer
Term
glycogen
Definition
-carb storage molecule in vertebrates
-greatest abundance in liver and muscle cells
-more compact than other polysaccharides
Term
proteoglycans
Definition
-class of carb-protein conjugates
-found on cell surface and in extracellular matrix
Term
glycoproteins
Definition
-class of carb-protein conjugates
-antibodies and other immune proteins, many hormones, structural proteins
Term
glycolipids
Definition
carbohydrate-lipid conjugates
Term
lipids
Definition
-contain C, H, O and sometimes P
-triglycerides, phospholipids, steriods, eiconsanoids
Term
lipid functions
Definition
cell membrane components, energy storage, hormones, vitamins, pigments, surface protection
Term
triglycerides
Definition
-neutral fats- solid fats and liquid oils
-large nonpolar molecules
-stored in adipocytes
-composed of 3 fatty acids bonded to a glycerol molecule
Term
glycerol
Definition
-modified simple sugar (sugar alcohol)
-backbone of phospholipid molecule
Term
fatty acids
Definition
-monocarboxylic acids typically containing hydrocarbon chains 12-20 carbons long
-numbered from c in c. acid
Term
triglyceride formation
Definition
-3 fatty acids are bound to glycerol by dehydration synthesis
-3 water molecules formed
Term
triglyceride functions
Definition
-energy storage (more reduced than carbs, energy released via oxidation, more energy released on oxid. than carbs)
-insulation
-protection under skin
Term
saturated fatty acids
Definition
-single bonds b/w C atoms (max # of H)
-solid animal fats, butter
Term
unsaturated fatty acids
Definition
-1 or more double bonds b/w C atoms
-1 double bond = monounsaturated
-multi-double bonds = polyunsaturated (plant oils, olive oil)
Term
clinical application of trans fats
Definition
-unsaturated fats w/trans-isomer fatty acid
-artificially hydrogenated (causes formation conversion of cis to trans DB)
-raises LDL, lowers HDL = heart disease
Term
phospholipid
Definition
-glycerol + 2 fatty acids and phosphorus (polar head) containing group
-head: polar
-tail: nonpolar
Term
steroids
Definition
-interlocking 4-ring structure
-ex. cholesterol, vit d, steroid hormones, bile salts
Term
cholesterol
Definition
-most important steroid
-liver can produce some
-in all cell membranes
Term
mineralocorticoids
Definition
-hormones that regulate sodium and other ion concentrations in body
-aldosterone
Term
glucocorticoids
Definition
-hormones that regulate metabolic processes
-cortisol
Term
bile salts
Definition
-emulsifying agents that influence fat absorption
-cholic acid
Term
nucleic acids
Definition
-comprise dna and rna (largest molecules in body)
-C, O, H, N, P
-building block = nucleotide
Term
nucleotides
Definition
-nitrogenous base
-pentose sugar
-phosphate group
Term
DNA composed of
Definition
-adenine, guanine, cytosine, and thymine
-deoxyribose (2 carbon)
Term
RNA composed of
Definition
-adenine, guanine, cytosine, and uracil
-ribose
Term
DNA
Definition
-double-stranded helical molecule in nucleus
-instructions for protein synthesis
-replicates before cell division
Term
RNA
Definition
-single-stranded molecule outside nucleus
-messenger, transfer, ribosomal RNA
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