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Definition
-'competent' bacteria -take up floating DNA |
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-infection by bacteriophage -virus may incorporate host DNA into bacteriophage capsid via homologous recombination -ex.vibrio cholerae-code for exotoxin |
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-bacterial mating -dependent on plasmids containing TRA genes -encode for sex pilus assembly (F-pilus) -DNA is transferred via sex pilus -can transfer antibiotic resistance genes |
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-movement of DNA from DNA molecule to DNA molecule -plasmid to genome, virus to plasmid, within plasmid -movement due to transposable elements (jumping genes) -transposase is enzyme responsible for excision and insertion |
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-gram negative -serotypes defined by O and H (flagellar) antigens -most common fermenter in animal GI tract -common cause of diarrhea -fecal oral transmission |
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-produce NO exotoxins -inflammatory response triggers prostaglandins triggers cAMP triggers fluid secretion |
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-gram positive -B binds -internalization -releases A -inactivates EF-2 -inhibits protein synthesis -cell death -damages? |
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-curved gram negative -B binds -internalization of A -activates AC -increases cAMP -releases ions/water |
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-gram positive -anthrax toxin (spores) -edema-AC activity, increases cAMP -lethal-protease activity, dec. MAPKK, apoptosis |
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Definition
-gram positive -tetanospasmin toxin inhibits inhibtor transmitter -spastic paralysis |
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-gram positive -toxin blocks release of ACh from vesicles -flaccid paralysis |
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Term
Enteropathogenic E. coli (EPEC) |
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Definition
-do not produce toxins -virulence factor is Intimin (adhesion) -Tir codes for receptor for Intimin -loss of microvilli in small intestine (loss of absorption) -A/E lesions? |
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bacterial entry zipper mechanism |
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Definition
-bind receptors -engulf by actin |
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Definition
-type 3 secretion -protein is sent to activate GTPase/actin polymerization -engulfed |
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