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-regulates bodies internal environment. -conducts signals from sensory receptors from within internal organs and relays this information to the CNS. Also relays signals back to organs from CNS. |
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parasympathetic nervous system |
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conserves energy to maintain bodily function in a vegetative state. |
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Na+ rushes into neuron until electrical potential across the membrane passes beyond zero to a reversed polarity-positive inside relative to outside |
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muscles twitch with stimulation to brain |
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Egyptian viewpoint of mind body problem |
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they believed consciousness and intelligence was mediated by the centrally located heart |
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Aristotle's evidence the heart is location of mind |
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1. the heart is warm and not cold as the brain
2. heart is first thing to form |
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Central Nervous System(CNS) |
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Fluid mechanical theroy- fluid forced in ventricals through nerves to move limbs |
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semipermeable membrane that encloses the neuron |
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the brain and mind are separate entities. |
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examines effects of drugs on the nervous system and the brain |
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R&R worker injured by tnt blast. -spike went through skull and frontal lobes |
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is produced by Chorid Plexus. -located in the ventricals of Cerebral Hemisphere. -125mL -Buoyancy-reduces momentum and acceleration of brain -waste collector- removes waste from neural metabolism |
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gaps between sections of myelin |
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gaps between adjacent neurons across which chemical signals are transmitted |
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fatty insulation around many axons |
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compares behavior of different species |
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ablation studies in pigeons -he attacked phrenology -he removed brain areas in pigeons to discover their functions |
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study psychological effects of brain damage |
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long, narrow, process that projects from the cell body |
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button like endings of the axon branches which release chemicals into synapses. |
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Franz Gall(Austrian Doctor) |
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-founder of phrenology-measuring of bumps on skull -personalty traits in certain brain parts caused displacement of skull -skull bumps represent brain bumps - |
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discoveries of 18th Century |
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1.brain communicates with body through nerves. 2.the brain generates electricity 3.brain follows laws of nature like a machine 4.different identifiable parts |
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studies relationship between physiological and psychological psychology |
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Darwin and natural selection |
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Behavior reflects activities of nervous system and brain mechanisms may be identical among species |
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study of neural mechanisms of behavior through direct manipulation of the brain through controlled experiments. |
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Sympathetic Nervous System |
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Part of the ANS. organizes and mobilizes energy sources during times of threat |
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Found damage in left frontal lobe of a patient who could understand language but could not speak. |
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short processes emanating from the cell body. |
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the cone shaped region at the junction between the axon and the cell body. |
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Hippocrates view of ind body problem |
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first to suggest link between mental events and brain |
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GLIA -nfluence the neurite outgrowth or rtraction -regulates chemical content of extra cellar space -controls concentration of several ions -affects synaptic transmission. |
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GLIA produces myelin spirals for multiple axons |
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Prduces myelin for only one axon |
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acts as phagocytes to remove debris |
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medulla oblongata- controls some reflexes ( heart rate, breathing, vomiting, sneezing) |
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cerebellum - involved in sensorimotor coordination and balance. May be more active in organizing sensory information that guides movement
-pons - (Latin for bridge) many axons in the pons cross from one side of the brain to the other. It contains nuclei for several cranial nerves |
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tectum - (Latin for roof) has 2 swellings: the superior colliculus (visual orienting) and inferior colliculus (auditory orienting)
-tegmentum - periaqueductal gray (pain), substantia nigra (motor movement) and ventral tegmental area (reward) |
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thalamus - made up of several different nuclei, especially important for relaying sensory information to the cerebral cortex. -hypothalamus - motivated behaviors, i.e. feeding, drinking & sex |
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Cerebral Cortex or Neocortex - 6 layered. The back half involved in sensory information. The front half involved in motor information or action |
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Hippocampus involved in memory for facts and possibly navigating in space. Pyriform cortex involved in memories for odors. -Amygdala (Latin for almond) - involved in emotional behavior for both positive and negative affect. |
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cooling just above freezing |
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Increases release and blocks reuptake of dopamine and norepinephrine |
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destroys DA (Dopamine) & 5-HT (Serotonin) axons -low doses releases dopamine; higher doses releases 5-HT |
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agonists: mimics the action of particular neurotransmitter molecules, e.g. nicotine 2. antagonist: blocks the actions of specific neurotransmitters, e.g. scopolamine |
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Inactivation and reuptake of neurotransmitters |
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. Breakdown with enzyme, e.g. acetylcholinesterase
2. Directly attach to protein and send back into the bouton, e.g. serotonin and catecholamines |
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Different types of presynaptic receptors |
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1. autoreceptor - sensitive to the neurotransmitter released by terminal bouton-acts as negative feedback 2. heteroreceptor - responds to chemical other than the neurotransmitter released by terminal bouton, e.g. nicotinic receptors at DA terminals |
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quick start (10 ms) with short duration (30 ms Immediately opens gates for ions Most abundant: glutamate (excitatory), Ionotropic synapses are used for quick events like visual stimulation, muscle movements, etc. |
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late start (30 ms) with duration up to hours activates G-protein inside membrane G-Protein activates second messenger system affects much of cell: opens or closes ion channels, changes protein production, or activates chromosomes in cell |
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Ca++ influx causes neuron to release neurotransmitter |
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Synthesis of small vs. large neurotransmitters |
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Small neurotransmitters synthesized in the bouton and packaged in vesicles, e.g. ACh Large neurotransmitters synthesized in the cell body by ribosomes and transported by microtubles, e.g. dynorphin |
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Excitory post synaptic potentials - increases the likelyhood a nearon will fire. |
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Inhibitory post synaptic potential- decreases the likeleyhood a nearon will fire. |
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