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1. Isolate cell content from the external environment 2. Regulate the exchange of essential substances 3. Allow communications between cells 4. Create attachments in and between cells 5. Regulate biochemical reactions |
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Phospholipids form a bilayer with hydrophilic heads and hydrophobic tails (with more saturated phospholipids are more fluid) (with more cholesterol are less fluid) |
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May be attached to membrane by a hydrophobic group. May be embedded in membrane. Many are glycoproteins (protein with a carbohydrate attached. |
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Receive and respond to messages from outside the cell |
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Glycoproteins with carbohydrates, on the outside of the membrane, cell specific |
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Promote chemical reactions |
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Anchored to cytoskeleton or extra cellular matrix or to other cells |
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1. Channel proteins = form a channel/ pore that selectively allows molecules to get through 2. carrier proteins = bind to and carry molecules across the membrane |
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Cell membranes are viewed as two-dimensional solutions of oriented globular proteins and lipids |
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Two Types = passive transport and energy-requiring transport |
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Diffusion of molecules or ions across membrane down a concentration gradient (high>low) -Simple diffusion -Facilitated diffusion -Osmosis |
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Very small molecules with no net charge |
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Hydrophilic molecules (ions/polar molecules) Channel proteins - selectivity for shape and charge of what they allow through the pore Carrier protein - endose protein to allow to go through / can change its shape to allow different proteins through |
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Diffusion of water across a selectively permeable membrane from a high concentration gradient to low (simple diffusion/facilitated by aquaporin channels) |
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Energy-Requiring Transport |
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Movement of molecules or ions across membrane agains concentration gradient (low>high) 1. Active Transport 2. Endocytosis 3. Exocytosis |
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Requires a protein that spans the membrane, a binding site specific to the molecule, and a binding site for energy carrier such as ATP |
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Engulfed by membrane into the cell. -Pinocytosis = liquids into cell -Receptor-mediated endocytosis = receptor based molecules into cell -Phagocytosis = engulfing large particles |
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Out of the cell. Membrane bound vesicles fused with a plasma membrane. |
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