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Sex linked traits Linked genes Fruit flies Mutant and wildtype |
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genes located on the same chromosome and do not assort independently |
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Recombinant ratio: less than 50% EX 1-49% |
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Genes are on the same chromosome |
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Recombinant ratio: 50 or greater |
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Check intermediate genes to see if it is sex linked or linked genes |
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What increases the likelihood of genes to cross over or recombinate |
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a farther distance between the two genes |
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Independent assortment will not occur when? |
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Genes are located on the same chromosome |
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Why did Morgan choose fruit flies? |
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A lot of offspring Quick reproduction time Four chromosome pairs 3 autosomal and 1 sexlinked |
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A gene is duplicated repeated gene segment lost fragment joins homologous chromosome |
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A lost gene reattaches backwards gene removed and replaced incorrectly |
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Swap genes on 2 different chromosomes lost fragment joins non homologous chromosome |
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a gene is deleted. Delete a gene |
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unactivated X in females randomly unactivated XXX 2 out of 3 are inactive which one will be inactive is random |
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If a nondisjunction gamete unites with a normal gamete you get the wrong number of chromosomes (abnormal) Two types: Monosomic 2n-1 Trisomic 2n+1 |
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Turner syndrom Monosomic Down-syndrom Trisomic |
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Affects only famales Genotype XO 45 chromosomes cant bare children one X Monosomy 2n-1 |
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47 chromosomes 3 #21 Trisomy 2n+1 |
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Wrong number of chromosomes 2n-1 2n+1 Can result in down-syndrom caused by: homologous pairs don't separate during Meiosis I sister chromatid don't separate during Meiosis II Result: 1 gamete gets 2 of the same kind of chromosome other gamete gets none |
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More than 2 complete sets of chromosomes 2 or more pairs common in plants rare in animals 4n 16n 32n meiosis never occurs |
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sex linked diseases to male offspring and female offspring |
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Sex linked diseases to female offspring pass Y chromosomes to Male offspring |
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Females are __________ for recessive sex linked diseases. What is their Genotype? |
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Carriers Heterozygous XBXb Disease is not expressed |
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Dominant sex linked diseases can or can't be carried? |
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Females Heterozygous XBXb |
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Male and Female can be carriers heterozygotes Bb |
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two of the same alleles can be Dominant BB or Recessive bb |
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What is seen Physical characteristics |
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Genetic make up Can't be seen physically |
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2 possible alleles 1 dominant one recessive Law of Segregation Independent Assortment went to F2 generation |
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chromosomes seperate each allele pair segregates |
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Meiosis chromosome pairs line up independently or the others (randomly) |
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None mendelian Inheritance: |
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Complete Opposite of Mendel's theories includes: Incomplete dominance Multiple alleles codominance epistasis polygenic inheritance pleotrophy |
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one allele is not completely dominant over the other EX Red flower X White flower BB X bb Gives you a pink flower Bb=pink mixed not blended (intermediate) |
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More than 2 alleles EX Blood type A dominant B dominant O recessive |
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Two dominant alleles are expressed equally EX Red and Blue scales in fish some scales are red some are blue EX AB blood type both show equally |
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one gene at one locus alters the phenotypic expression of another gene at another EX fur color in Labradors 2 genes for fur color 1 is present or absent presence or absence of pigment (ee)=no pigment =yellow lab if it does not have ee and has pigment it is either chocolate (bb) or black (BB Bb) |
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multiple genes influence one phenotypic characteristic not either/or EX skin color 3 genes all incompletely dominant AABBCC=darkest aabbcc=lightest AABbcc=aaBBCc intermediate combinations |
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ability of gene to have multiple phenotypic effects Ex Siamese cats Sick cell disease |
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heritable units specific location on chromosomes |
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specific location of a gene |
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variants of a character black hair brown hair blonde hair |
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heritable features that varies among individuals |
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heritable features that varies among individuals |
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identical to parents PPXpp=Pp |
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When would you use a test cross? |
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If an organism's appearance does not reveal its genetic composition PP Pp, determine with test crosses Cross unknown with recessive PP X pp Pp X pp |
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YYRR X yyrr two traits 9:3:3:1 ratio |
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What makes A blood and B blood different between O blood? |
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A and B blood have polysacharide molecules on blood cells O blood has no molecules on blood cells |
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O blood A and B are also co dominant AB blood type expressed equally |
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6 possible genotypes for blood types are: |
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A Blood: Genotype/Rejects/Accepts: |
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Genotype: AA AO Rejects: BB BO AB Accepts: A, O |
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Genotype: BB BO Reject: AA AO AB Accepts: B, O |
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AB Blood Genotype/Rejects: |
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Genotype: AB Rejects: NONE Universal acceptor |
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Genotype: OO Rejects: AA, AO, BB, BO, AB Universal Donor |
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more likely to stay together during meiosis |
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Crossing over is responsible for: |
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individuals that dont look like parents |
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XXY yields a _________ male. |
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