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Biology Final
Lectures 15-22
183
Biology
Undergraduate 1
12/10/2007

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Term
Transferring a phosphate group to some other molecule
Definition
Phosphorylation
Term
Three Types of Cellular Work
Definition
Mechanical, transport, and chemical
Term
Chemical agent that speeds up a reaction without being consumed by the reaction
Definition
catalyst
Term
catalytic protein that lowers the Ea barrier but do not affect change in free-energy
Definition
enzyme
Term
reactant that an enzyme acts on
Definition
enzyme substrate
Term
what forms when an enzyme binds to its substrate at the active site
Definition
enzyme-substrate complex
Term
How does the active site lower the Ea barrier
Definition
-orienting substrates correctly
-straining substrate bonds
-providing a favorable microenvironment
-covalently bonding to the substrate
Term
nonprotein enzyme helpers
Definition
cofactors
Term
organic cofactors
Definition
coenzymes
Term
bind to the active site of an enzyme, competing with the substrate
Definition
competitive inhibitors
Term
bind to another part of an enzyme, causing the enzyme to change shape and making the active site less effective
Definition
noncompetitive inhibitors
Term
cases where a proteins function at one site is affected by binding of a regulatory molecule at another site, that may inhibit or stimulate an enzyme's activity
Definition
allosteric regulation
Term
stabilizes active form of enzyme
Definition
activator
Term
stabilizes the inactive form of the enzyme
Definition
Inhibitor
Term
what prevents a cell from wasting chemical resources by synthesizing more product than needed
Definition
feedback inhibition
Term
generation of oxygen and organic molecules to be used in cellular respiration
Definition
photosynthesis
Term
create energy by breaking down organic fuels
Definition
catabolic pathways
Term
partial degradation of sugars without oxygen
Definition
fermentation
Term
consummation of oxygen and completely degrades organic molecules, yielding a much greater amount of ATP
Definition
cellular respiration
Term
substance loses electrons
Definition
oxidation
Term
substance gains electrons
Definition
reduction
Term
electron donor
Definition
reducing agent
Term
electron receptor
Definition
oxidizing agent
Term
coenzyme that functions as an electron acceptor
Definition
NAD+
Term
break down glucose into two molecules
Definition
glycolysis
Term
completes the breakdown of glucose
Definition
citric acid cycle
Term
"splitting of sugar"; harvests energy by oxidizing
Definition
glycolysis
Term
produced during glycolysis, three carbon organic acid
Definition
pyruvate
Term
two major phases of glycolysis
Definition
-energy investment phase
-energy payoff phase
Term
the use of energy in a H+ gradient to drive cellular work
Definition
chemiosmosis
Term
pyruvate is converted to ethanol by releasing CO2
Definition
alcohol fermentation
Term
pyruvate reduced by NADH to lactate with no release of CO2
Definition
lactic acid fermentation
Term
long molecule consisting of monomers
Definition
polymer
Term
three organic polymers
Definition
-carbs
-proteins
-nucleic acids
Term
monomers form with large molecules
Definition
dehydration reaction
Term
polymers are disassembled into monomers
Definition
hydrolysis
Term
multiples of CH20, major fuel for cells and as raw material for building molecules
Definition
monosaccharides
Term
dehydration reaction joins two monosaccharides
Definition
disaccharides
Term
covalent bond between two monosaccharides
Definition
glycosideic linkage
Term
storage polysaccharide that consists mostly of glucose monomers
Definition
starch
Term
unbranched starch
Definition
amylose
Term
branched starch
Definition
amylopectin
Term
storage in animals that is highly branched. In humans, mainly stored in liver and muscle cells
Definition
glygogen
Term
major component of tough walls of plant cells; polymer of glucose that has either alpha or beta glucosidic linkages
Definition
cellulose
Term
structural polysaccharide found in cell walls of fungi
Definition
chitin
Term
3-carbon alcohol with hydroxyl group
Definition
glycerol
Term
three fatty acids joining to glycerol by ester linkage
Definition
fatty acids
Term
maximum number of hydrogen atoms, no double bonds; solid @ room temp; contributes to CVD through plaque deposits
Definition
saturated fatty acids
Term
one or more double bonds; liquid @ room temp
Definition
unsaturated fatty acids
Term
3 functional groups of proteins
Definition
-nonpolar
-polar
-electrically charged
Term
polymer of amino acids linked by peptide bonds
Definition
polypeptide
Term
unique sequence of amino acids, determined by inherited genetic information
Definition
primary structure
Term
coils and folds in polypeptide chain, either alpha helix or beta pleated sheet
Definition
secondary structure
Term
determined by interactions among various side chains (ionic bonds, hydrogen bonds, disulfide bridges)
Definition
tertiary structure
Term
a change in the genetic makeup of a population from generation to generation
Definition
microevolution
Term
results when two or more polypeptide chains form one macromolecule
Definition
quaternary structure
Term
fibrous protein consisting of 3 polypeptides
Definition
collagen
Term
globular protein consisting of 4 polypeptides
Definition
hemoglobin
Term
what affects conformation of protein structure?
Definition
-alterations in pH
-salt concentration
-temperature
-other environmental factors
Term
loss of proteins original conformation
Definition
denaturation
Term
boundary that separates living cell from nonliving surroundings
Definition
plasma membrane
Term
model that proteins are dispersed within the fluid bilayer with only hydrophilic regions exposed to h20
Definition
fluid mosaic model
Term
cool temperatures cause membranes to become more ____________
Definition
solid
Term
helps to stabilize membrane structure
Definition
membrane proteins
Term
6 major functions of membrane proteins
Definition
-transport
-enzymatic
-signla transduction
-cell to cell recognition
-intercellular joining
-attachment to cytoskeleton and ECM
Term
allows passage of hydrophilic substances and are specific to the substance it moves
Definition
transport proteins
Term
allow H20 to pass through membrane
Definition
aquaporins
Term
bind to molecules and change shape to shuttle across membrane
Definition
carrier proteins
Term
diffusion of substance across a membrane with no energy investment
Definition
passive transport
Term
tendency of molecules to spread out evenly into available space; randomly dispersed
Definition
diffusion
Term
diffusion of h20 across selectively permeable membrane
Definition
osmosis
Term
ability of solution to cause a cell to gain or lose water
Definition
tonicity
Term
cell loses water; concentration greater outside cell
Definition
hypertonic
Term
cell gains water; concentration greater inside cell
Definition
hypotonic
Term
transport proteins speed up movement of molecules across plasma membrane
Definition
facilitated diffusion
Term
provide corridors that allow a specific molecule or ion to cross the membrane
Definition
channel proteins
Term
undergo subtle change in shape that translocates the solute-binding site across the membrane
Definition
carrier proteins
Term
moves substances across concentration gradient via ATP
Definition
active transport
Term
totality of organism's chemical reactions
Definition
metabolism
Term
organisms convert energy to light
Definition
bioluminescence
Term
release energy by breaking down complex molecules into simpler compounds
Definition
catabolic pathways
Term
consume energy to build complex molecules
Definition
anabolic pathways
Term
energy associate with motion
Definition
kinetic energy
Term
energy that matter possesses
Definition
potential energy
Term
1st law
Definition
-energy is constant
-can be transferred
-cannot be created/destroyed
Term
2nd law thermodynamics
Definition
-energy transfer increases entropy and that some energy is lost
Term
net release of free energy and is spontaneous
Definition
exergonic
Term
absorbs free energy from surrounds and is not spontaneous
Definition
endergonic
Term
study of how populations change genetically over time; integrates Mendelian genetics with Darwinian theory of evolution by natural selection
Definition
population genetics
Term
focuses on populations as units of evolution
Definition
modern synthesis
Term
localized group of individuals capable of inter-breeding and producing fertile offspring
Definition
population
Term
total aggregate of genes in a population at any one time
Definition
gene pool
Term
describes a population that is not evolving; states that frequencies of alleles and genotypes in a population's gene pool will remain constant from generation to generation
Definition
Hardy-Weinberg theorem
Term
Conditions of HWE
Definition
-no mutations
-large population size
-no gene flow
-no natural selection
-random mating
Term
changes in nucleotide sequence of DNA; cause new genes and alleles to arise
Definition
mutations
Term
describes how allele frequencies fluctuate unpredictably from one generation to the next; reduces genetic variation through loss of alleles
Definition
genetic drift
Term
sudden change in the environment that drastically reduces size of population and remaining individuals do not reflect the original gene pool
Definition
bottleneck effect
Term
occurs when few individuals become isolated from a larger population. Ex, small group of organisms become isolated and start a new population
Definition
founder effect
Term
causes a population to gain or lose alleles; reduces differences between populations over time
Definition
gene flow
Term
requires genetic variation to be present; certain alleles are passed to the next generation
Definition
Natural selection
Term
distinct phenotype; either-or basis
Definition
discrete characters
Term
vary along a continuum within a population. Ex, skin colour or height
Definition
quantitative characters
Term
describes a population in which two or more distinct varieties are common throughout the population
Definition
phenotypic polymorphism
Term
looks at variable traits that cause differences. Ex, how similar DNA between individuals is
Definition
heterozygosity
Term
measures the average percent of loci that are heterozygous in a population
Definition
average heterozygosity
Term
a quantitative trait that varies over geographical extent
Definition
cline
Term
contribution an individual makes to the gene pool of the next generation, relative to the contributions of other individuals
Definition
fitness
Term
favors individuals at one end of the phenotypic range
Definition
directional selection
Term
favors individuals at both extremes of the phenotypic range
Definition
disruptive selection
Term
favors intermediate variatns and acts against extreme phenotypes
Definition
stabilizing selection
Term
natural selection for mating success
Definition
sexual selection
Term
marked differences between the sexes in secondary sexual characteristics
Definition
sexual dimorphism
Term
competition among individuals of one sex for mates of the opposite sex
Definition
intrasexual selection
Term
occurs when individuals of one sex (usually females) are choosy in selecting their mates. Ex, may depend on showiness of male's apperance
Definition
intersexual selection
Term
refers to evolutionary change above the species level. Longer periods of time, and from one species to another species
Definition
macroevolution
Term
transforms one species into another. Changing within lineage over time
Definition
anagenesis (phyletic evolution)
Term
splitting of a gene pool, giving rise to one or more new species
Definition
cladogenesis (branching evolution)
Term
splitting of a gene pool, giving rise to one or more new species
Definition
cladogenesis (branching evolution)
Term
cannot reproduce with other species, different from their own. Ex, humans
Definition
biological species concept
Term
factors that impede two species from producing viable, fertile hybrids; two types of barriers: prezygotic and postzygotic
Definition
reproductive isolation
Term
two species encounter rarely because of different habitats (prezygotic)
Definition
habitat isolation
Term
species that don't interbreed because of timing of reproduction occurs at different times (prezygotic)
Definition
temporal isolation
Term
same habitat, same reproduction schedule but have different rituals or behaviors for courtship (prezygotic)
Definition
behavioral isolation
Term
morphological differences can prevent successful mating. Ex, flowers that have different polinators (prezygotic)
Definition
mechanical isolation
Term
sperm of one species is not able to fertilize eggs of another species (prezygotic)
Definition
gametic isolation
Term
genes of different parent species may interact and impair the hybrid's development. Genetic abnormalities/weaker (postzygotic)
Definition
reduced hybrid viability
Term
hybrids are sterile, often due to failure in meiosis. Ex, donkey + horse = mule (postzygotic)
Definition
reduced hybrid fertility
Term
first generation hybrids are fertile but when they mate with another species or with parent species, offspring of next generation are feeble or sterile (postzygotic)
Definition
hybrid breakdown
Term
limits of biological species (does not apply to)
Definition
-asexual organisms
-fossils
-organisms with little known about their reproduction
Term
defines a species by structural features; corresponds with biological species concept (Linnaus)
Definition
morphological species concept
Term
focuses on morphologically discrete species known only from fossil records
Definition
paleontological species concept
Term
views a species in terms of its ecological niche; differ based on ecology but can't identify reproduction isolation
Definition
ecological species concept
Term
defines a species as a set of organisms with a unique genetic history. Ex, lineages, branches, or phylogentic tree
Definition
phylogenetic species concept
Term
gene flow interrupted or reduced when population is divided into geographically isolated subpopulations
Definition
allopatric speciation
Term
parent populations overlap geographically
Definition
sympatric speciation
Term
presence of extra sets of chromosomes due to accidents during cell division.
Definition
polyploidy
Term
evolution of diversely adapted species from a common ancestor upon introduction to new environmental opportunities
Definition
adaptive radiation
Term
describes periods of apparent stasis punctuated by sudden change; Stephen Jay Gould
Definition
punctuated equilibrium
Term
proportioning that helps give a body its specific form
Definition
allometric growth
Term
evolutionary change in the rate or timing of developmental events
Definition
heterochrony
Term
rate of reproductive development accelerates compared with somatic development
Definition
paedomorphosis
Term
determines asic features as where wings and legs develop
Definition
homeotic genes
Term
provide positional info in the development of fins in fish and limbs in tetrapods. Duplication important in evolution of vertebrates
Definition
hox genes
Term
eat autotrophs (plants & algae)
Definition
herbivores
Term
eat other animals
Definition
carnivores
Term
eat animals or autotrophs
Definition
omnivores
Term
eat dead matter
Definition
detritivores
Term
adequate diet needs
Definition
-fuel for all cellular work
-organic raw materials for biosynthesis
-essential nutrients
Term
stored excess calories in the liver and muscles, and as fat
Definition
glycogen
Term
major fuel for cells
Definition
glucose
Term
reduces glucose levels by signaling liver and muscle tissue to make glycogen. secreted when blood glucose levels rise after eating
Definition
insulin
Term
stimulates glycogen breakdown, secreted from the liver when the blood glucose levels drop
Definition
glucagon
Term
diet deficient in calories
Definition
undernourishment
Term
excessive calorie intake
Definition
overnourishment
Term
excess stored fat
Definition
adipose tissue
Term
secreted by empty stomach to promote hunger
Definition
ghrelin
Term
produced by adipose tissue to reduce hunger
Definition
leptin
Term
limited essential nutrients
Definition
malnutrition
Term
diet with insufficient essential amino acids
Definition
protein deficiency
Term
unsaturated fatty acids
Definition
essential fatty acids
Term
organic molecules required in small amounts
Definition
vitamins
Term
simple inorganic nutrients
Definition
minerals
Term
process of breaking down food into molecules small enough to absorb
Definition
digestion
Term
uptake of nutrients by body cells
Definition
absorption
Term
food particles engulfed by endocytosis and digested within food vacuoles
Definition
intracellular digestion
Term
breakdown of food particles outside cells, in compartments with the outside of the animal's body
Definition
extracellular digestion
Term
passage of undigested material out of the digestive compartment
Definition
egestion
Term
part of alimentary canal that stores food
Definition
crop
Term
part of alimentary canal that mechanically digests food
Definition
gizzard
Term
enzymatic digestion, acidifcation
Definition
stomach
Term
absorption of nutrients
Definition
intestine
Term
secrete digestive juices through ducts; salivary glands, pancreas, liver, and gallbladder
Definition
accessory glands
Term
rhythmic contractions of muscles in the wall of the alimentary canal
Definition
peristalsis
Term
initiates breakdown of glucose polymers into maltose
Definition
salivary amylase
Term
made up of HCl and Pepsin, secreted from stomach to converts meal to acid chyme
Definition
gastric juice
Term
lesions in the lining when the mucus fails and the stomach digests some of itself
Definition
gastric ulcers
Term
protein-digesting enzymes produced in the pancreas, that are activated after entering the duodenum
Definition
proteases
Term
aids in digestion and absorption of fats; breaks down fats
Definition
bile
Term
epithelial lining of duodenum that produces several digestive enzymes
Definition
brush border
Term
where acid chyme mixes with digestive juices from pancreas, liver, gallbladder, and small intestine
Definition
duodenum
Term
hormone that inhibits gastrin production
Definition
enterogastrone
Term
molecules made from glycerol and fatty acids mixed with cholestoral, and transported into lacteals
Definition
chylomicrons
Term
lymphatic vessel that allows amino acids and sugars to enter blodstream
Definition
lacteal
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