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biology 101 schoolcraft college chapter 3
book is biology concepts & connections by reece, taylor, simon, and dickey
121
Biology
Undergraduate 1
07/15/2012

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Term
Carbon
Definition
Life’s Molecular Diversity is Based on the Properties of 
Term
carbon
Definition

Different molecules found in cells are composed of carbon bonded to other carbons and atoms of other elements.

 
Term
organic compounds.
Definition
Carbon-based molecules are called 
Term
sharing electrons
Definition
carbon can form four covalent bonds with other atoms by
Term
Hydrocarbons
Definition
are molecules composed of only hydrogen and carbon.
Term
Hydrocarbons
Definition

tend to be non-polar molecules because they are made only of C and H.  Examples:

CH4 is methane

C3H8 is propane

C8H18 is octane

 
Term
carbon skeletons (chain of carbon atoms in organic molecules).
Definition

There are a variety of hydrocarbon structures.

They are represented by

Term

1.  Length.   Carbon skeletons vary in length.

Branching. Skeletons may be unbranched or branched.
 
Double bonds.  Skeletons may have double bonds
Rings Skeletons may be arranged in rings
Definition

Four Ways That Carbon Skeletons Can Vary 

 
Term
isomers
Definition
Compounds with the same molecular formula but different structural arrangements or shapes are call
Term
The different shapes of isomers 
Definition
result in unique properties on how they function!
Term

Size and shape of its carbon skeleton

2)  Groups of atoms (functional groups) attached to it.

 
Definition

There are two basic parts to an organic molecule:

 
Term
functional group 
Definition
affects a biological molecule’s function in a characteristic way.
Term
polar
Definition
The first five functional groups in this table all make their molecules 
Term
hydrophilic
Definition
This polarity tends to make the compounds containing these groups 
Term
Hydrophilic = 
Definition
water -loving” which means these compounds are soluble or dissolve in water
Term
Hydroxyl group:   –OH
Definition

Consists of a hydrogen atom bonded to an oxygen atom. Organic compounds containing this group are known as alcohols. 

Examples:

CH3OH is methanol

C2H5OH  is ethanol

C3H7OH is 2-propanol or isopropyl alcohol

What is isopropyl alcohol? Have you ever usedthis compound? 

Term
Carbonyl group
Definition
A carbon atom linked by a double bond to an oxygen atom.  
Term
aldehyde.
Definition
If the carbonyl group is at the end of a carbon skeleton, then the molecule is an
Term
ketone
Definition
If the carbonyl group is within a carbon skeleton, the molecule is a
Term
Carboxyl group; -COOH
Definition
A carbon atom linked by a double bond to an oxygen atom and also bonded to a hydroxyl group.  
Term
carboxylic acids
Definition
The carboxyl group acts as an acid by contributing an H+ to solution and becoming ionized.  Compounds with carboxyl groups are called 
Term
.  Amino group  –NH2
Definition
A nitrogen atom is bonded to two hydrogen atoms and a carbon skeleton
Term
amines
Definition
Organic molecules with an amino group are called 
Term
Phosphate Group; -OPO32-:
Definition

Consists of a phosphorus atom bonded to four oxygen atoms.

Molecules with phosphate groups are often involved in energy transfer such as ATP (adenosine triphosphate)

 
Term
functional groups
Definition
Male and female sex hormones differ only in 
Term
Limited Set of Small Molecules
Definition
Cells Make a Huge Number of Large Molecules from a 
Term

1.  Carbohydrates2.  Proteins

Lipids4.  Nucleic acids

 
Definition

There are four classes of molecules important to organisms:

 
Term
macromolecules
Definition
The four classes of biological molecules contain very large molecules called 
Term
Polymers
Definition
are large molecules made by stringing together smaller, identical or similar building blocks (monomers).
Term
Monomers
Definition
are the building blocks of polymers.
Term
monomers and polymers
Definition

Think of a train (polymer) consisting of a chain of cars (monomers).

 
Term

The variety of polymers is what makes organism unique.  The monomers used to make those polymers are universal.

 
Definition

Cells make their diverse macromolecules from about 40-50 common monomers and a few rare ones.

There are about a trillion different proteins (polymer) that are made from only 20 different amino acids (monomer).

The proteins in your body and those in a tree or an ant are all assembled from the same 20 amino acids, they are just arranged in different sequences!

DNA (polymer) is built from just four kinds of nucleotides (monomer).

 
Term
polymers 
Definition
Cells make most of their macromolecules by joining monomers into chains of 
Term
dehydration reaction
Definition
Cells link monomers to form polymers through a 
Term
Dehydration reactions 
Definition
removes a molecule of water from two molecules that will be joined in the process.
Term
the reverse process, hydrolysis.  
Definition

Polymers are broken down to monomers by 

 
Term

= water 

 break 

Definition
Hydro ; lysis 
Term
by adding water to them
Definition
A hydrolysis reaction breaks covalent bonds between monomers by 
Term

Protein(polymer)Amino acids (monomers)

 
Definition

Most of the organic molecules in your food are polymers and are too big to enter your cells.  So they have to be broken down into monomers.

 
Term
Carbohydrates
Definition
range from small sugar molecules (monomers) to large polysaccharides such as starch molecules in pasta and potatoes.
Term
Carbohydrate monomers (single-unit sugars) 
Definition
are called monosaccharides.
Term
Monosaccharides
Definition
have a number of hydroxyl groups and a carbonyl group. 
Term
Monosaccharides (especially glucose) 
Definition

are the main fuels for cellular work

Also used as raw materials to manufacture other organic molecules such amino acids and fatty acids.

 
Term
isomers
Definition

Glucose and fructose are

They contain the same atoms (C6H12O6) but in different arrangements.

These minor differences give different properties e.g. fructose taste much sweeter

 
Term
disaccharide in a dehydration reaction
Definition
Two monosaccharides (monomers) can bond to form a
Term
Polysaccharides
Definition
are polymers composed of hundreds to thousands of monosaccharides linked together by dehydration reactions
Term
Polysaccharides
Definition

function as:

Storage molecules

Structural compounds

 
Term
 many = sugar
Definition

Poly = ; sacchar = 

 
Term
Starch 
Definition

is composed of glucose monomers.

Used by plants for energy storage – “carb bank”

Humans and animals can hydrolyze (break down) plant starch to glucose.

Potatoes, wheat, corn and rice are examples of starches in the human diet.

Term
Glycogen 
Definition

is composed of glucose monomers.

Used by YOU and animals for energy storage – “carb bank”

Glycogen is stored in human muscle and liver cells.

 
Term
Cellulose 
Definition

is composed of glucose monomers but is arranged differently than glycogen and starch.

Component of plant cell walls – very tough!

Its bonds cannot be hydrolyzed by most animals – so cellulose is not a nutrient for humans – but it does contribute to digestive system health

Term
insoluble fiber
Definition

From a nutrition standpoint, cellulose is known as 

It passes through our digestive tract unchanged and provides the “bulk” for our stools.

We obtain it by eating fruits, vegetables, and whole grains.  Remember, we gain no nutrients from cellulose. 

 Cows and termites have cellulose-hydrolyzing microorganisms in their digestive tracts – so they can derive fuel from cellulose.

 
Term
Carbohydrates 
Definition

are usually hydrophilic (water-loving) due to their hydroxyl groups (-OH).

Cotton bath towels which are mostly cellulose, are highly water absorbent!

 
Term
Lipids 
Definition
consist mainly of carbon and hydrogen atoms (2X more H than C, and very few O) linked by nonpolar covalent bonds – this makes them hydrophobic, or water-fearing compounds.
Term
they are smaller molecules and NOT built from monomers
Definition
Lipids differ from carbohydrates, proteins, and nucleic acids in that 
Term
Lipids 
Definition
This group of molecules includes fats and oils, phospholipids, and steroids.
Term
hydrophobic molecules 
Definition
Non-polar bonds means lipids are 
Term
long-term energy storage.
Definition
The main functions of lipids is 
Term
cushioning vital organs, insulating the body, make up part of the cell membrane, and make up components of hormones and steroids.
Definition
Other functions of lipids are
Term
Fats 
Definition
are lipids that are mostly long-term storage molecules.
Term
fat 
Definition
is a large lipid made from two kinds of smaller molecules, glycerol and fatty acids.
Term
triglycerides
Definition
Fats are also known as 
Term
triglycerides
Definition
consist of a glycerol linked to three fatty acids
Term
Glycerol 
Definition
is an alcohol with 3 carbon atoms.  Each carbon atom is attached to a hydroxyl group (-OH). 
Term
fatty acid 
Definition
consists of a hydrocarbon chain (16 -18 C) and a carboxyl group (-COOH).
Term
triglyceride
Definition

is a fat molecule consisting of three fatty acids linked to glycerol.

 
Term
have at least one double bond in the fatty acid portion in the molecule. This means the molecule contains less than the maximum number of hydrogen atoms
Definition
Unsaturated fatty acids (fats
Term
Saturated fatty acids (fats) 
Definition
have all single bonds in the fatty acid portion of the molecule
Term
Saturated fats
Definition
are solid at room temperature.
Term
Unsaturated fats 
Definition
are liquid at room temperature.
Term
Hydrogenated
Definition
” vegetable oils are unsaturated fats that have been converted to saturated fats in the lab by adding hydrogen atoms.
Term
heart disease.
Definition
Diets high in trans fats and saturated fats increase risk of 
Term
Phospholipids 
Definition
are structurally similar to fats but contain only two fatty acids (not three) attached to glycerol and contain a negatively charged phosphate group.
Term
Phospholipids 
Definition
are a major component of cell membranes.
Term
bilayer (two layers).
Definition
Within the cell membrane phospholipids cluster together into a 
Term
head
Definition
of a phospholipid molecule contains the negatively charged phosphate group and is hydrophilic (water–loving). 
Term
tails
Definition
of a phospholipid molecule are the two fatty acids and are hydrophobic (water-fearing).
Term
Steroids 
Definition

Steroids are lipids in which the carbon skeleton contains four fused rings (3 six-sided rings and one five-sided ring).

 
Term
Cholesterol 
Definition

is a common component in animal cell membranes and is the starting material for making other steroids such as sex hormones (estrogen, testosterone).

 
Term
Anabolic steroids
Definition

Are synthetic variants of testosterone

Mimic testosterone and can cause a buildup of muscle and bone mass

They are prescription drugs and are often prescribed to treat general anemia and some diseases that destroy body muscle

Term
protein 
Definition
is a polymer made up of amino acid monomers.
Term
Proteins 
Definition
are composed of differing arrangements of a common set of just 20 amino acid monomers.
Term
enzymes
Definition
Probably the most important role for proteins is as 
Term
enzymes
Definition
proteins that act as catalysts that speed up and regulate the chemical reactions within cells.
Term
Structural proteins 
Definition
make up hair, nails, skin, tendons, ligaments (collagen, elastin, keratin).
Term
Contractile proteins 
Definition
(actin, myosin) are found in muscles and aid in movement.
Term
Defensive proteins
Definition
such as antibodies of the immune system (gamma globulin).
Term
Signal proteins (hormones)
Definition
that help coordinate body activities by communicating between cells (insulin).
Term
Transport proteins
Definition
hemoglobin – delivers O2 to cells in the body).
Term
Storage proteins 
Definition
which serve as source of amino acids for developing embryos (ovalbumin
Term

Each amino acid is composed of:

 
Definition
An amino group
A carboxyl group (which makes it an acid)
Central carbon atom
R group (side chain) – which determines the specific properties of each of the 20 amino acids used to make proteins. 
Term
Depending on the composition of their R group
Definition
amino acids are classified as either hydrophobic (nonpolar) or hydrophilic (polar).
Term
dehydration reaction
Definition
Cells link amino acid monomers together by a 
Term
peptide bond.
Definition
The bonds between amino acid monomers is a 
Term
polypeptide
Definition
Additional amino acids can be added by the same process to create a chain of amino acids called a 
Term
polypeptide
Definition
are about 1000 amino acids in length and have a unique sequence – but it is not a protein.
Term
functioning protein 
Definition
is composed of one or more polypeptide chains precisely twisted and coiled together into a unique 3-D shape
Term
amino acid sequence 
Definition
causes the polypeptide to assume a particular shape.
Term
Lysozyme 
Definition
is an enzyme in sweat, tears, and saliva.  Its specific shape helps bind to its target (bacteria) which fits into its groove
Term
denaturation
Definition
a polypeptide chain unravels, loses its shape, and loses its function
Term
Proteins can be denatured by changes in
Definition
in salt concentration, pH, or by high heat.
Term

Primary structure

Secondary structure

Tertiary structure

Quaternary structure

 
Definition
A protein has four levels of structure
Term
primary structure 
Definition
determines the shape of the protein which ultimately determines its function
Term
cell’s genetic information (DNA
Definition
The correct amino acid sequence is determined by
Term
secondary structure 
Definition
is the coiling or folding of the chain, stabilized by hydrogen bonding
Term
Alpha helix
Definition
Coiling of the polypeptide chain will form this structure.
Term
Beta pleated sheet
Definition
:  Formed by a certain kind of folding of the polypeptide chain – found in silk proteins in spider webs.
Term
tertiary structure 
Definition
is the overall three-dimensional shape of a polypeptide.
Term
hydrogen bonding and/or covalent bonds between sulfur atoms (
Definition
The tertiary structure is held together by 
Term
quaternary structure 
Definition
results from the association of two or more polypeptide chains
Term
DNA (Deoxyribonucleic acid) and RNA (Ribonucleic acid) 
Definition
are nucleic acids composed of monomers called nucleotides
Term

Five-carbon sugar called ribose in RNA and deoxyribose in DNA

2) A phosphate group

3) A nitrogenous base

DNA nitrogenous bases are adenine (A), thymine (T),cytosine (C), and guanine (G).

RNA also has A, C, and G, but instead of T, it has uracil (U).

 
Definition
Nucleotides have three parts
Term
double helix.
Definition
DNA consists of two polynucleotide strands wrapped around each other to form a DNA 
Term
RNA
Definition
by contrast, is a single-stranded polynucleotide
Term
Stretches of a DNA molecule called genes 
Definition
program the amino acid sequence of a protein.
Term
DNA 
Definition
stores genetic information and passes that information from one generation to the next.
Term
DNA
Definition
contains the instructions for the primary sequence of a polypeptide/protein
Term
RNA
Definition
is the intermediary or middleman that conveys those instructions to the protein-making machinery in the cell that assembles the amino acids in the designated order to make the correct polypeptide/protein.
Term
Lactose 
Definition
is the disaccharide sugar found in milk and other dairy products.  It is formed from glucose and galactose
Term
lactase
Definition
In order to digest lactose, your digestive system uses an enzyme called
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