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Life’s Molecular Diversity is Based on the Properties of |
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Different molecules found in cells are composed of carbon bonded to other carbons and atoms of other elements.
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Carbon-based molecules are called |
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carbon can form four covalent bonds with other atoms by |
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are molecules composed of only hydrogen and carbon. |
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tend to be non-polar molecules because they are made only of C and H. Examples:
CH4 is methane
C3H8 is propane
C8H18 is octane
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carbon skeletons (chain of carbon atoms in organic molecules). |
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There are a variety of hydrocarbon structures.
They are represented by |
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1. Length. Carbon skeletons vary in length.
Branching. Skeletons may be unbranchedor branched.
Double bonds. Skeletons may have double bonds
Rings Skeletons may be arranged in rings
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Four Ways That Carbon Skeletons Can Vary
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Compounds with the same molecular formula but different structural arrangements or shapes are call |
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The different shapes of isomers |
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result in unique properties on how they function! |
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Size and shape of its carbon skeleton
2) Groups of atoms (functional groups) attached to it.
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There are two basic parts to an organic molecule:
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affects a biological molecule’s function in a characteristic way. |
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The first five functional groups in this table all make their molecules |
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This polarity tends to make the compounds containing these groups |
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water -loving” which means these compounds are soluble or dissolve in water |
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Consists of a hydrogen atom bonded to an oxygen atom. Organic compounds containing this group are known as alcohols.
Examples:
CH3OH is methanol
C2H5OH is ethanol
C3H7OH is 2-propanol or isopropyl alcohol
What is isopropyl alcohol? Have you ever usedthis compound? |
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A carbon atom linked by a double bond to an oxygen atom. |
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If the carbonyl group is at the end of a carbon skeleton, then the molecule is an |
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If the carbonyl group is within a carbon skeleton, the molecule is a |
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A carbon atom linked by a double bond to an oxygen atom and also bonded to a hydroxyl group. |
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The carboxyl group acts as an acid by contributing an H+ to solution and becoming ionized. Compounds with carboxyl groups are called |
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A nitrogen atom is bonded to two hydrogen atoms and a carbon skeleton |
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Organic molecules with an amino group are called |
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Phosphate Group; -OPO32-: |
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Consists of a phosphorus atom bonded to four oxygen atoms.
Molecules with phosphate groups are often involved in energy transfer such as ATP (adenosine triphosphate)
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Male and female sex hormones differ only in |
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Limited Set of Small Molecules |
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Cells Make a Huge Number of Large Molecules from a |
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1. Carbohydrates2. Proteins
Lipids4. Nucleic acids
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There are four classes of molecules important to organisms:
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The four classes of biological molecules contain very large molecules called |
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are large molecules made by stringing together smaller, identical or similar building blocks (monomers). |
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are the building blocks of polymers. |
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Think of a train (polymer) consisting of a chain of cars (monomers).
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The variety of polymers is what makes organism unique. The monomers used to make those polymers are universal.
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Cells make their diverse macromolecules from about 40-50 common monomers and a few rare ones.
There are about a trillion different proteins (polymer) that are made from only 20 different amino acids (monomer).
The proteins in your body and those in a tree or an ant are all assembled from the same 20 amino acids, they are just arranged in different sequences!
DNA (polymer) is built from just four kinds of nucleotides (monomer).
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Cells make most of their macromolecules by joining monomers into chains of |
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Cells link monomers to form polymers through a |
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removes a molecule of water from two molecules that will be joined in the process. |
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the reverse process, hydrolysis. |
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Polymers are broken down to monomers by
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A hydrolysis reaction breaks covalent bonds between monomers by |
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Protein(polymer)Amino acids (monomers)
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Most of the organic molecules in your food are polymers and are too big to enter your cells. So they have to be broken down into monomers.
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range from small sugar molecules (monomers) to large polysaccharides such as starch molecules in pasta and potatoes. |
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Carbohydrate monomers (single-unit sugars) |
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are called monosaccharides. |
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have a number of hydroxyl groups and a carbonyl group. |
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Monosaccharides (especially glucose) |
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are the main fuels for cellular work
Also used as raw materials to manufacture other organic molecules such amino acids and fatty acids.
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Glucose and fructose are
They contain the same atoms (C6H12O6) but in different arrangements.
These minor differences give different properties e.g. fructose taste much sweeter
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disaccharide in a dehydration reaction |
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Two monosaccharides (monomers) can bond to form a |
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are polymers composed of hundreds to thousands of monosaccharides linked together by dehydration reactions |
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function as:
Storage molecules
Structural compounds
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is composed of glucose monomers.
Used by plants for energy storage – “carb bank”
Humans and animals can hydrolyze (break down) plant starch to glucose.
Potatoes, wheat, corn and rice are examples of starches in the human diet. |
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is composed of glucose monomers.
Used by YOU and animals for energy storage – “carb bank”
Glycogen is stored in human muscle and liver cells.
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is composed of glucose monomers but is arranged differently than glycogen and starch.
Component of plant cell walls – very tough!
Its bonds cannot be hydrolyzed by most animals – so cellulose is not a nutrient for humans – but it does contribute to digestive system health |
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From a nutrition standpoint, cellulose is known as
It passes through our digestive tract unchanged and provides the “bulk” for our stools.
We obtain it by eating fruits, vegetables, and whole grains. Remember, we gain no nutrients from cellulose.
Cows and termites have cellulose-hydrolyzing microorganisms in their digestive tracts – so they can derive fuel from cellulose.
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are usually hydrophilic (water-loving) due to their hydroxyl groups (-OH).
Cotton bath towels which are mostly cellulose, are highly water absorbent!
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consist mainly of carbon and hydrogen atoms (2X more H than C, and very few O) linked by nonpolar covalent bonds – this makes them hydrophobic, or water-fearing compounds. |
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they are smaller molecules and NOT built from monomers |
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Lipids differ from carbohydrates, proteins, and nucleic acids in that |
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This group of molecules includes fats and oils, phospholipids, and steroids. |
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Non-polar bonds means lipids are |
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long-term energy storage. |
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The main functions of lipids is |
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cushioning vital organs, insulating the body, make up part of the cell membrane, and make up components of hormones and steroids. |
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Other functions of lipids are |
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are lipids that are mostly long-term storage molecules. |
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is a large lipid made from two kinds of smaller molecules, glycerol and fatty acids. |
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consist of a glycerol linked to three fatty acids |
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is an alcohol with 3 carbon atoms. Each carbon atom is attached to a hydroxyl group (-OH). |
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consists of a hydrocarbon chain (16 -18 C) and a carboxyl group (-COOH). |
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is a fat molecule consisting of three fatty acids linked to glycerol.
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have at least one double bond in the fatty acid portion in the molecule. This means the molecule contains less than the maximum number of hydrogen atoms |
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Unsaturated fatty acids (fats |
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Saturated fatty acids (fats) |
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have all single bonds in the fatty acid portion of the molecule |
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are solid at room temperature. |
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are liquid at room temperature. |
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” vegetable oils are unsaturated fats that have been converted to saturated fats in the lab by adding hydrogen atoms. |
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Diets high in trans fats and saturated fats increase risk of |
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are structurally similar to fats but contain only two fatty acids (not three) attached to glycerol and contain a negatively charged phosphate group. |
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are a major component of cell membranes. |
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Within the cell membrane phospholipids cluster together into a |
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of a phospholipid molecule contains the negatively charged phosphate group and is hydrophilic (water–loving). |
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of a phospholipid molecule are the two fatty acids and are hydrophobic (water-fearing). |
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Steroids are lipids in which the carbon skeleton contains four fused rings (3 six-sided rings and one five-sided ring).
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is a common component in animal cell membranes and is the starting material for making other steroids such as sex hormones (estrogen, testosterone).
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Are synthetic variants of testosterone
Mimic testosterone and can cause a buildup of muscle and bone mass
They are prescription drugs and are often prescribed to treat general anemia and some diseases that destroy body muscle |
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is a polymer made up of amino acid monomers. |
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are composed of differing arrangements of a common set of just 20 amino acid monomers. |
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Probably the most important role for proteins is as |
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proteins that act as catalysts that speed up and regulate the chemical reactions within cells. |
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make up hair, nails, skin, tendons, ligaments (collagen, elastin, keratin). |
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(actin, myosin) are found in muscles and aid in movement. |
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such as antibodies of the immune system (gamma globulin). |
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Signal proteins (hormones) |
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that help coordinate body activities by communicating between cells (insulin). |
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hemoglobin – delivers O2 to cells in the body). |
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which serve as source of amino acids for developing embryos (ovalbumin |
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Each amino acid is composed of:
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–An amino group
–A carboxyl group (which makes it an acid)
–Central carbon atom
–R group (side chain) – which determines the specific properties of each of the 20 amino acids used to make proteins. |
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Depending on the composition of their R group |
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amino acids are classified as either hydrophobic (nonpolar) or hydrophilic (polar). |
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Cells link amino acid monomers together by a |
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The bonds between amino acid monomers is a |
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Additional amino acids can be added by the same process to create a chain of amino acids called a |
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are about 1000 amino acids in length and have a unique sequence – but it is not a protein. |
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is composed of one or more polypeptide chains precisely twisted and coiled together into a unique 3-D shape |
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causes the polypeptide to assume a particular shape. |
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is an enzyme in sweat, tears, and saliva. Its specific shape helps bind to its target (bacteria) which fits into its groove |
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a polypeptide chain unravels, loses its shape, and loses its function |
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Proteins can be denatured by changes in |
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in salt concentration, pH, or by high heat. |
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Primary structure
Secondary structure
Tertiary structure
Quaternary structure
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A protein has four levels of structure |
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determines the shape of the protein which ultimately determines its function |
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cell’s genetic information (DNA |
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The correct amino acid sequence is determined by |
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is the coiling or folding of the chain, stabilized by hydrogen bonding |
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Coiling of the polypeptide chain will form this structure. |
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: Formed by a certain kind of folding of the polypeptide chain – found in silk proteins in spider webs. |
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is the overall three-dimensional shape of a polypeptide. |
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hydrogen bonding and/or covalent bonds between sulfur atoms ( |
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The tertiary structure is held together by |
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results from the association of two or more polypeptide chains |
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DNA (Deoxyribonucleic acid) and RNA (Ribonucleic acid) |
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are nucleic acids composed of monomers called nucleotides |
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Five-carbon sugar called ribose in RNA and deoxyribose in DNA
2) A phosphate group
3) A nitrogenous base
DNA nitrogenous bases are adenine (A), thymine (T),cytosine (C), and guanine (G).
RNA also has A, C, and G, but instead of T, it has uracil (U).
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Nucleotides have three parts |
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DNA consists of two polynucleotide strands wrapped around each other to form a DNA |
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by contrast, is a single-stranded polynucleotide |
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Stretches of a DNA molecule called genes |
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program the amino acid sequence of a protein. |
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stores genetic information and passes that information from one generation to the next. |
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contains the instructions for the primary sequence of a polypeptide/protein |
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is the intermediary or middleman that conveys those instructions to the protein-making machinery in the cell that assembles the amino acids in the designated order to make the correct polypeptide/protein. |
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is the disaccharide sugar found in milk and other dairy products. It is formed from glucose and galactose |
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In order to digest lactose, your digestive system uses an enzyme called |
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