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Biology 101 - Chapter 03
Biology 101 - Chapter 03 Molecules of Life
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Biology
Undergraduate 1
10/13/2013

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Term
Organic compounds
Definition
carbon-based molecules
Term
hydrocarbons
Definition
contain only carbon and hydrogen atoms
Term
functional groups
Definition
groups of atoms directly involved in chemical reactions
Term
macromolecules
Definition
polymers

ex: carbohydrates, starch, proteins
Term
polymers
Definition
large molecules made by stringing together many smaller molecules called monomers
ex: pearl necklace is polymer, single pearls are monomers
Term
monomers
Definition
smaller molecules that join together to create a polymer
Term
dehydration reaction
Definition
chemical reaction that removes a molecule of water while creating a polymer
Term
hydrolysis
Definition
breakdown of bonds between monomers by adding a water molecule
Term
Carbohydrates
Definition
molecules that include sugars and polymers of sugars
in animals: primary source of dietary energy and raw material for manufacturing other kinds of organic compounds
in plants: serve as building material for plant body
Term
monosaccharides
Definition
monomers of carbohydrates; cannot be broken down into smaller sugars
ex: glucose (found in sports drinks)
fructose (found in fruit)
both are found in honey
Term
isomers
Definition
molecules that have the same molecular formula but different structures

ex: anagrams - earth, heart
Term
glucose
Definition
main fuel molecules for cellular work, aqueous solution called dextrose often given as an IV to sick or injured patients.
Term
disaccharide
Definition
double sugar, constructed from two monosaccharides by a dehydration reaction
ex: lactose, maltose, sucrose
Term
lactose
Definition
"milk sugar"
made from glucose and galactose
Term
maltose
Definition
naturally found in germinating seeds
two glucose monomers joined together
used to make beer, malt whiskey & liquor, malted milk shakes, malted milk ball candy
Term
sucrose
Definition
glucose monomer linked to a fructose monomer
main carb in pant sap
Term
high-fructose corn syrup
Definition
manufactured by the breakdown of starch from corn to glucose and converted to fructose
main sweetner for the United States.
Term
polysaccaride
Definition
complex carbs, polymers of monosaccharides
ex: starch, glycogen, cellulose
Term
starch
Definition
long strings of glucose monomers
plant cells store starch, like we do glycogen
ex: potatoes, grains, corn and rice
Term
glycogen
Definition
polymer of glucose monomers, but more extensively branched than starch.
stored in liver and muscles, which breakdown the glycogen and release glucose when energy is needed
Term
cellulose
Definition
polymer of glucose, but linked together in a unique way
most abundant organic compound on earth, forms cable-like fibrils in tough walls that enclose plant cells.
cellulose in plant fods, pass unchanged through our system, commonly known as dietary fiber
ex: fruits and veggies, whole grains, bran and beans
Term
hydrophilic
Definition
readily dissolving in water
(monosaccharides and disaccharides)
Term
hydrophobic
Definition
does not mix with water
(lipids)
ex: vinegar and oil
Term
lipids
Definition
neither macromolecules nor polymers
diverse group of molecules made from different "building blocks"
ex: fat and steroids
Term
fat
Definition
triglycerides, unsaturated and saturated
Term
triglycerides
Definition
glycerol molecule joined with three fatty acids
Term
unsaturated
Definition
fatty acid has fewer than the max number of hydrogens at the double bond
Term
saturated
Definition
contain max number of hydrogen atoms
Term
polyunsaturated fat
Definition
several double bonds within its fatty acids
Term
atherosclorosis
Definition
lipidcontaining deposits called plaque build up along the inside walls of blood vessels, reducing blood flow and increasing risk of heart attacks and strokes

caused by diets rich in saturated fat
Term
hydrogenation
Definition
converting unsaturated fat to saturated fat by adding hydrogen
also createstrans fats, a type of unsaturated fat that is particularly bad for your health
Term
omega-3 fatty acids
Definition
fats that are good for you, reduce risk of heart disease and relieve symptoms of arthritis and inflammatory bowel disease
ex: nuts and oily fish such as salmon
Term
steroids
Definition
hydrophobic, very different from fats in structure and function
all steroids have a carbon skeleton with four fused rings
ex: cholesterol, testosterone, estrogen
Term
cholesterol
Definition
has a bad reputation because of its association with cardiovascular disease, but it is an essentional molecule in your body. Key component of membranes that surround your cells.
Term
protein
Definition
polymer of amino acid monomers
most elaborate and diverse of life's molecules
(polymer consisting of one or more polypeptides)
Term
amino acids
Definition
20 kinds, consist of a central carbon atom bonded to four covalent partners, three of those attachments are common to all 20 amino acids
carboxyl group (-COOH), amino group (-NH2) and a hydrogen atom
varient component is the "R group" or "radical group"
Term
R group
Definition
unique to each amino acid, defines it's special chemical properties.
Term
peptide bond
Definition
bond between adjacent amino acids by a dehydration reaction
Term
polypeptide
Definition
resulting long chain of amino acids after peptide bonds
Term
primary structure
Definition
specific amino acid sequence (spelling) of a polypeptide
Term
sickle-cell disease
Definition
caused by substitution of one amino acid for another at a particular position in the hemoglobin
Term
protein shape
Definition
3-4 levels of structure
primary, secondary, tertiary and quaternary
proteins with one polypeptide chain contain first 3 levels
proteins with more than one polypeptide chain contains all four
Term
primary structure of protein
Definition
unique secquence of amino acids in polypeptide chain
Term
secondary structure of protein
Definition
alpha and pleated sheet, reinforced by hydrogen bonds along the polypeptide backbone
Term
tertiary structure
Definition
overall three-dimentional shape reinforced by chemical bonds between the side groups of amino acids and different regions of the polypeptide chain
Term
quaternary structure
Definition
proteins with two or more polypeptide chains have a quaternary structure, results from bonds between the chains
Term
protein form
Definition
when a cell makes a polypeptide, the chain usually folds spontaneously to form the functional shape
function depends on its ability to recognize and bind to some other molecule
function follows form
Term
denaturation of protein
Definition
shape of protein is sensitive to the surrounding environment
ex: unfavorable change of temperature, pH or some other quality of the environment can cause a protein to unravel and lose its normal shape
Term
nucleic acids
Definition
macromolecules (polymers) that store information and provide instructions for building proteis
ex: DNA, RNA
Term
DNA
Definition
deoxyribonucleic acid
genetic material that humans and other organisms inherit from their parents consist of giant molecules of DNA
Term
gene
Definition
specific stretch of DNA that programs the amino acid sequence of a polypeptide, written in chemical code that must be translated from "nucleic acid language" to "protein language"
Term
RNA
Definition
molecules that make the "nucleic acid language" to "protein language" translation
Term
nucleotides
Definition
monomer used to make nucleic acid polymers, contain three parts
center is a five-carbon sugar, deoxyribose in DNA and ribose in RNA
attached to sugar is negatively charged phosphate group containing a phosphorus atom bonded to oxygen atoms
also attached to sugar is nitrogen-containing base made of one or two rings
sugar and phosphate are the same in all nucleotides; only the base varies
Term
DNA nucleotide
Definition
has one of four possible nitrogenous bases:
(A) adenine
(G) guanine
(C) cytosine
(T) thymine
cystosine
Term
polynucleotides
Definition
monomers joined together by dehydration reactions
if DNA...called a DNA strand
Term
sugar-phosphate backbone
Definition
covalent bonds between sugar of one nucleotide and the phosphate of the next
leaves the bases (A,T,C or G) hanging off the backbone like appendages
Term
double helix
Definition
molecule of cellular DNA, double stranded with two polynucleotide strands wrapped around each other
bases along one DNA strand hydrogen-bond to bases along the other strand. Individually weak, like water molecules, but collectively they zip the two strands together into a very stable double helix
Term
lactose intolerance
Definition
lactose intolerance is rare among americans of northern european descent because the ability to tolerate lactose offered a survival advantage to their ancestors. Lactose intolerant people cannot break down lactose. Result of having a neucleotide at a specific location, 14000 nucleotides away from the lactace gene, on one chromosome.
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