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BIOL 101
thomas ryan
98
Biology
Undergraduate 3
02/05/2009

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Term
Discovery Science
Definition
Discovery of new information on what we can record, conserve or measure
Term
Inductive Reasoning
Definition
Using specific observations to form general theories Ex. Cell theory
Term
Seven steps of Scientific Method
Definition
observation, question, hypothesis, prediction, perform a controlled experiment, analyze results, conclusion
Term
Scientific Theory
Definition
A hypothesis that has never been disproved after many years of rigorous testing
Term
Organic Compound
Definition
A compound containing carbon, which makes 4 bonds usually with hydrogen, oxygen and sometimes sulfur, phosphorous and nitrogen
Term
condensation reaction
Definition
a reaction in which water is lost to the environment. Covalent bonds are created.
Term
Hydrolysis
Definition
breaking polymers into monomers. Water has to be added to molecules from environment.
Term
Monomers
Definition
simple sugars. Monosaccharides.
Term
Glucose
Definition

C6H12O6 the main fuel for our cells

Term
Fructose
Definition

C6H12O6 corn syrup

Term
Galactose
Definition

C6H12O6 found in milk

Term
Disaccharides
Definition
2 monosaccharides joined by condensation
Term
Lactose
Definition
milk sugar, galactose and glucose
Term
sucrose
Definition
table sugar, major sugar in plant sap, fructose and glucose
Term
Maltose
Definition
malt sugar, glucose and glucose
Term
Starch
Definition
glucose polymer, glucose storage in plants
Term
cellulose
Definition
glucose polymer, structural molecules for plants; aka fiber. Animals can’t hydrolyze it
Term
Glycogen
Definition
glucose polymer, glucose storage for animals; found in abundance in liver and muscle cells
Term
chitin
Definition
glucose polymer; structural molecules for animals with exoskeleton
Term
Lipids
Definition
'fats'. Hydrophobic. The main biological functions of lipids include energy storage, acting as structural components of cell membranes, and participating as important signaling molecules.
Term
triglyceride
Definition
energy storage molecule. Insulation and padding in animals. Less than 150 mg/dL
Term
Glycerol
Definition
an alcohol with 3 –OH groups
Term
Monomer
Definition
glycerol and fatty acids
Term
polymer
Definition
1 glycerol combined with 3 fatty acids
Term
Unsaturated fats
Definition
Fatty acid chains containing some double bonds; therefore the chains do not pack tightly--> Liquid at room temperature, "good" fats from nutrition point of view, mainly from plants
Term
Saturated fats
Definition
fatty acid chain lack double bonds; therefore chains pack tightly--> solid at room temperature. 'bad' from the nutrition point of view. From animals
Term
Trans fats
Definition
made when manufactures add hydrogen to vegetable oil-- a process called hydrogenation.
Term
Phospholipids
Definition
are a class of lipids and are a major component of all cell membranes. They form a lipid bilayer within a cell membrane. They also transport DNA. They are amphiphilic- head likes water, tail does not. Their monomer- phosphorous head and 2 fatty acids
Term
waxes
Definition
Lipid. monomer: 1 long fatty acid and alcohol group (or alcohol chain). They are more hydrophobic than fats.
Term
Steroids
Definition
monomer: 4 carbon rings and no fatty acids.
Term
Cholesterol
Definition
Steroid found in abundance in the cell membranes of eukaryotic cells; it is a precursor to making many other important steroids
Term
LDL
Definition
Low density lipoprotein. bad cholesterol. 130mg/dL
Term
HDL
Definition
high density lipoprotein. Good cholesterol. higher than 40 mg/dL
Term
Amino acids
Definition
they are monomers. there are 20 different types of them. Made up of an amino group(NH3+), carboxyl group (COO-) and R group. They have different properties according to the R group they have
Term
polypeptides
Definition
Three or more amino acids.
Term
Protein structure #1
Definition
The amino acid sequence. held together by strong covalent peptide bonds.
Term
protein structure #2
Definition
Held together by weak hydrogen bonds between the amino groups of one amino acid and the carboxyl group of another amino acid. Could be either alpha-helix (coil) or beta-pleated (folds)
Term
protein structure #3
Definition
held together by unique interactions between R-groups. often used for transport. Fibrous proteins consist mostly of alpha helices. Globular proteins consist of mix between alpha-helices and beta plates sheets.
Term
protein structure #4
Definition
must be interaction between 2 or more polypeptide sub-units.
Term
Mutation in DNA
Definition
change in first structure of a protein.
Term
Prions
Definition
misfolded protein that is resistant to normal cellular degradation in the brain cells and has the ability to convert nomal folding protein into this misfolded type. If a cell becomes clogged with them, neurons die. Ex. mad cow disease, OJD, scrapie.
Term
Protein functions
Definition
structural, contractile(changing shape and causes contractions) , storage of amino acids, defensive, transport, signaling, enzymes.
Term
DNA
Definition
made up of nucleotides.made up of deoxyribose (sugar) a negatively charged phosphate group, and one of the 4 nitrogen bases (Adenine, Thymine, Guanine, Cytosine). Has a double helix structure (2 polynucleotides wrapped around each other). Adenine to thymine, and guanine to cytosine.
Term
RNA
Definition
nucleotides made up of ribose(sugar), phosphate group, and one of 4 nitrogenous bases (adenine, uracil, guanine, cytosine). Single stranded, 1 polynucleotide.
Term
ALL cells have..
Definition
plasma membrane, hereditary material (DNA), and cytoplasm (water-based semi-fluid). Cell size is constrained by the surface area to volume ratio.
Term
Fluid mosaic
Definition
Used to describe the cell membrane. fluid- very flexible. mosaic- made up also of proteins, phospholipids, cholesterol, glycol (sugar) proteins, glycolipid
Term
Prokaryotic cells
Definition
"before kernel" No nucleus. Surface projections, cell wall, capsule, plasma membrane, chromosome, ribosomes
Term
Ribosomes
Definition
made up of rRNA (ribosomal) and proteins. They catalyze the formation of peptide bonds during translation.
Term
Eubacteria
Definition
1/2 major groups of prokaryotic cells. "true bacteria"
Term
Archae
Definition
more complex than eubacteria, live in extreme environments (very salty, hot, or methane environ.)
Term
Eukaryotic
Definition
'true kernel'. have nucleus
Term
chromatin
Definition
all of the cell's linear chromosomes. Humans have 46 chromosomes.
Term
Nuclear envelope for eukaryotic cells
Definition
two phospholipid bilayers and large pores.
Term
nucleolus
Definition
ribosome factory
Term
Rough Endoplasmatic Reticulum(RER)
Definition
Stacked, flattened discs of membrane, continuous, with ribosomes. Proteins being made at RER ribosomes are inserted into RER for folding.
Term
Smooth Endoplasmic Reticulum
Definition
SER. has no ribosomes. continuous with the RER, has tubular membranes. They use enzymes to synthesize lipids. These lipids can be attached to proteins, used to make hormones, used to make new membranes, and to detoxify liver
Term
Golgi Bodies
Definition
flattened stacks of membrane, not continuous with the ER. They are responsible for the the chemical modification from the ER.
Term
Lysosomes
Definition
Membrane-enclosed vesicle. It holds the digestive enzymes.
Term
central vacuole
Definition
in plants. One very large vesicle, used for the storage of ions, sugars and amino acids.
Term
Path from proteins to outside
Definition
nucleus--> rough ER--> smooth ER--> golgi body-->out of cell
Term
Ribosomes in cytoplasm
Definition
They are responsible for the proteins that are staying inside the cells
Term
Mitochondria
Definition
all eukaryotic cells have them. They transfer the energy in carbohydrates to ATP (cellular energy)in the presence of oxygen.Structure- inner and outer membranes, intermembrane material is called matrix, folds of the inner membrane are called cristae
Term
Chloroplasts
Definition

In plants and some protists. they trap sunlight with photosynthetic pigments to make carbohydrates.

 [image]

Term
Microtubules
Definition
in cytoskeleton. Long, hollow cylinders; made of tubulin subunits (proteins). "railroad track" for organelles and chromosomes. they can assemble and disassemble.
Term
microfilaments
Definition
two coiled strands of actin subunits (protein). Responsible for general cell movement, cell pinching during cell division in animal cells. they can assemble and disassemble.
Term
Intermediate filaments
Definition
ropelike, made up of various fibrous proteins. They serve as support, cages in nucleus.
Term
Flagella(long) and cilia (short)
Definition
9 + 2 doublet arrangement of microtubules
Term
basal body
Definition
the place where the flagella and cilia are anchored into the cytoplasm. The structure in cross section is 9 triplets of microtubules
Term
Dynein
Definition
a motor protein. it walks along the neighboring microtubules so that they can slide past each other resulting in a whipping motion.
Term
pseudopods
Definition
temporary lobes that project from the cell, used in locomotion and in food capture.
Term
cell walls
Definition
consist of carbohydrates. found in prokaryotes, plants and some protists. Plants have a primary cell wall made of cellulose, and some plant cells have a secondary cell made of lignin(wood).
Term
cell junction
Definition
in plants: pores in the cell wall for communication are called plasmodesmata.
in animals: leakproof junctions between cells(water tight) are tight junctions. Adhering junctions are "spot welds" strongly holding cells together. Open channels linking the cytoplasm of neighboring cells are gap junctions.
Term
Cell membranes
Definition
made of phospholipid bilayer. They allow oxygen, carbondioxide, some water, and some small non-polar molecules. With the help of transporter proteins they allow large molecules(glucose), large polar molecules, ions, water soluble molecules.
Term
concentration gradient
Definition
high to low concentration
Term
diffusion
Definition
particles move spontaneously with the concentration gradient.[image]
Term
osmosis
Definition
moves water from low solute concentraion to high solute concentration.
Term
hypotonic
Definition
low concentration of solutes
Term
hypertonic
Definition
high concentration of solutes
Term
isotonic
Definition
equal concentration of solutes
Term
facilitated diffusion (passive transport)
Definition
Uses transporter proteins to allow large or charged molecules to move through the hydrophobic core. They move with the concentration gradient. Ex. glucose uptake into cells.
Term
Active transport
Definition
move molecules against concentration gradient. It requires cellular energy (ATP) and transport protein. Ex. calcium pump.
Term
Exocytosis
Definition
membrane enclosed vesicle fuses with plasma membrane and the contents are spilled out
Term
endocytosis
Definition
plasma membrane invaginates and brings a vesicle into cytoplasm.
Term
phagocytosis
Definition
cellular eating, endocytosis of large molecules
Term
pinocytosis
Definition
endocytosis of small droplets, cellular drinking.
Term
Receptor mediated endocytosis
Definition
Highly specific; an invagination forms on membrane with receptors for a specific molecule.
Term
Enzymes
Definition
end in "-ase". They increase the rate of reaction by lowering energy of activation barrier(the minimum amount of energy needed to start a reaction)
Term
competitive inhibitor
Definition
inhibits a reaction by binding to the active site. Disallowing the substrate from binding.
Term
non-competitive inhibitor
Definition
inhibitor binds to a site on the outside of the active site but can cause the active site to change shape.
Term
feedback inhibition
Definition
when a product of a reaction is also the inhibitor (in order to make more product)
Term
endergonic reaction
Definition
products have more energy than the reactants.
Term
exergonic reaction
Definition
energy out--> products have less energy than the reactants
Term
ATP
Definition
cellular energy. they spend energy during endergonic reactions and gain energy during exergonic reactions. They are made up of adenine, ribose, and 3 phosphates. The last phosphate can be hydrolyzed. ADP+P-->ATP
Term
Glycolosis
Definition
Reaction where energy releasing pathways begin. They occur in the cytoplasm and they split up 1 glucose to produce 2 molecules of pyruate. Small amounts of ATP are generated, as well as NADH.
Term
Aerobic respiration
Definition
main energy-releasing pathway leading to ATP formation; it occurs in the mitochondria
Term
Fermentation Pathways (anaerobic respiration)
Definition
can release small quantities of energy without the use of oxygen; they occur in the cytoplasm.
Term
Krebs cycle
Definition
degrades pyruvate to carbon dioxide; ATP is produced; and the electron shttlers NAD+ and FAD, accept H+ and e- to be carried to the electron transfer chain. 6 carbon molecule is rearranged, two CO2 are release, 2H+ 4 e- are transferred to 2 NAD+ to become 2 NADH
Term
Electron transfer posphorylation
Definition
processes the H+ and electrons to generate high yields of ATP; the final electron acceptor is oxygen.
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