Term
| List 3 steps in fatty Acid (FA ) Metabolism |
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Definition
1) Activation
2) Transport across mitochondria membrane
3) Beta Oxidation |
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Term
| Steps In Activation of FA |
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Definition
1) FA + ATP => acyl- adelnlate
2) acyl - adenlyale + CoASH => acyl- CoA |
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Term
Enzyme involve in formation of acyl- CoA
from acyl- adenylate |
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Definition
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Term
Medium Acyl - CoA Synthetase
Long Acyl - CoA Synthetase |
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Definition
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Term
| Function of inorganic pyrophosphotases |
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Definition
| Provides energy to drive the 2 step activation |
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Term
| What is the pourpose of Carnitine Palmitoyl Transferase I |
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Definition
| Convert Acyl - CoA to Acyl- carnitine |
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Term
| What is the pourpose of Carnitine Acyltransferase |
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Definition
| Antiport that transport carnitine out into the cytosol and acyl- carnitine into the mitochondria matrix |
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Term
| Wher is Carnitine Acyltransferase located |
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Definition
| Located on the mitochondrial membrane |
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Term
| What is the function of Carnitine Palmitoyl Transferase II |
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Definition
Converts Acyl- carnitine to acyl-CoA
In the mitochondria |
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Term
| What are the steps involved in beta oxidation? |
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Definition
1) Reduction of alpha and beta carbons
2) Hydration of the enoyl- CoA
3) Oxidation of the beta carbon
4) Catalysis of thiolytic cleavage |
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Term
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Definition
| Oxidise the alpha and beta carbons of teh acyl- CoA to form Trans Enol- CoA |
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Term
| What intermediate accepts the eletrons from teh oxidation of Acyl-CoA? |
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Definition
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Term
| What intermediate accepts the eletrons from teh oxidation of Acyl-CoA? |
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Definition
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Term
| What enzyme is responsible for the formation of 3L Hydroxy Acyl- CoA? |
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Definition
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Term
| Can Enyol- CoA Hydratase convert cis enoyl- CoA to 3D hydroxyacyl-CoA? |
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Definition
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Term
| 3-L Hydroxyacyl-CoA DH functions to? |
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Definition
| Oxidize the beta Carbon to a ketone |
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Term
|
Definition
catalyzes thiolytic cleavage to produce
Acetyl-CoA & fatty acyl-CoA (2 C shorter). |
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Term
| Intermidates and Products of beta oxidation of Fatty acids |
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Definition
Acetyl-CoA & fatty acyl-CoA (2 C shorter).
b-Ketoacyl-CoA
3L-hydroxyacyl-CoA
Trans Enoyl - Co A |
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Term
Match enzymes that are responsible for the production if the intermediates.
Acetyl-CoA & fatty acyl-CoA (2 C shorter).
b-Ketoacyl-CoA
3L-hydroxyacyl-CoA
Trans Enoyl - Co A |
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Definition
Beta - Ketiacyl - CoA thiolase
Enoyl-CoA Hydrayase
Acyl- CoA DH
3L Hydroxyacyl-CoA DH |
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Term
| Whis Step in Fatty Acid Oxidation produces NADH & FADH2? ( What enzymes) |
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Definition
Acyl- CoA DH - FADH
3L Hydroxyacyl-CoA DH |
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Term
| # ATP required to initiate 1 Fatty Acid oxidation |
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Definition
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Term
| # ATP derived from 1 actyl CoA |
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Definition
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Term
| Number of Acetyl Co A per Fatty Acid(Cn) |
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Definition
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Term
| #FADH2 produced per Fatty acid (Cn) |
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Definition
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Term
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Definition
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Term
| # water used per Fatty acid (Cn) |
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Definition
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Term
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Definition
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Term
| In the catabolism of odd # FA, what are the two products of metabolism ? |
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Definition
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Term
| Enzyme responsible for the synthesis of (s) Methylmalonyl CoA |
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Definition
| Propionyl- CoA carboxylase |
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Term
| Racemix of (R) and (S) methylmalonyl -CoA are in equilibrium |
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Definition
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Term
| Function of Methylmalonyl CoA mutase? |
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Definition
| converts Methylmalonyl CoA to Succinyl - CoA which is ised in the TCA cycle |
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