Term
Energy Content in kcal/g and KJ/g
Fat:
Carb:
Protein:
Alcohol: |
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Definition
Fat: 9 kcal/g and 38 KJ/g
Carb: 4 kcal/g and 17KJ/g
Protein: 4 kcal/g and 17 KJ/g
Alcohol: 7 kcal/g and 29 KJ/g |
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Term
3 Metabolic routes of Fuels, Vitamins, Minerals, Water, Xenobiotics |
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Definition
Digestions
Absorption
Transport |
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Term
Dietary Fuels are Oxidized to form?
Fats:
Carbs:
Proteins:
Alcohol: |
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Definition
Fats: CO2 + H2O
Carbs: CO2 + H2O
Proteins: CO2 + H2O + NH4+
Alcohol: CO2 + H2O |
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Term
ATP -> ADP + Pi
Energy is Utilized through (5 ways): ____________
ADP -> ATP
Energy is produced through (1 way): ___________ |
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Definition
Utilized through
Biosynthesis, Detoxification, Muscle Contraction, Ion Transport, Thermogensis
Produced by
OXIDATION |
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Term
4 steps in oxidation of Carbs, lipids, and proteins to produced ATP:
1. Hydrolyzed to form ___ + ____ + ____
2. Then each are degraded to form _________
3. Enters the TCA cycle to form _____ and _____
4. ATP is produced by ______ _______ and released by Electron Transport Chain |
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Definition
1. Glucose, Fatty Acids, Amino Acids
2. Acetyl CoA
3. NADH2 and FADH
4. Oxidative Phosphorylation |
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Term
Define + Know how to Calculate
1. RDA:
2. BMR:
3. DEE: |
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Definition
1. Recommended Daily Allowance
How much you are allowed to consume each day
2. Basal Metabolic Rate
Energy needed for daily maintanence of organs
3. Daily Energy Expenditure
BMR + Food + Activity |
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Term
3 Monosaccharides are ___ ____ ____
Provides _____ for cells
3 Disaccharides are ___ ____ ___
______ to produce glucose
3 Polysaccharides are _____ ____ ____
Used for energy _____
Conjugated Carbohydrates are components of the ___ _____ |
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Definition
Glucose, Galactose, Fructose
Provide Energy for cell
Sucrose, Lactose, Maltose
Digested
Starch, Cellulose, Glycogen
Energy Storage
Components of the cell surface |
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Term
Sucrose breaks down to: Glucose and ______
Maltose breaks down to: Glucose and ______
Lactose breaks down to: Glucose and ______ |
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Definition
Sucrose: Glucose + Fructose
Maltose: Glucose + Glucose
Lactose: Glucose + Galactose |
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Term
Nitrogen Balance:
Determined by _____ _____
Positive examples: ____ ____ ____
Negative examples: ____ ____
Neutral examples: _______ |
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Definition
Nitrogen Balance:
Determined by Amino acids
Positive examples: Growth, Recovery, Pregnancy
Negative example: Stress, poor-diet
Neutral: general health |
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Term
3 Major Electrolytes: ___ ___ ___
Electrolytes create ____ gradients, maintain ______, neutralize ______
4 Major Minerals: ___ ___ ___ ___
___ and ___ are used for structural components
*____* required or metabolic function of ATP
___ is a component of Hemoglobin in blood |
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Definition
3 Major Electrolytes: Na+,K+,Cl-
Electrolytes create ion gradients, maintain water-balance, neutralize ion-charges
4 Major Minerals: Ca, P, Fe, Mg
Ca and P are used for structural components
*Mg* required or metabolic function of ATP
Fe is a component of Hemoglobin in blood
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Term
4 Dificiencies of Fat Soluble Vitamins
Vitamin A:
Vitamin D:
Vitamin E:
Vitamin K: |
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Definition
Vitamin A: Night blindness
Vitamin D: Rickets or Osteomalacia
Vitamin E: Musclular Dystrophy
Vitamin K: Anemia or Blood clotting |
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Term
Know the categories of water-soluble vitamins:
1. Energy Metabolism: ___,___,___,___,____
2. Amino Acid Metabolism: ______ includes ___ and ____.
3. RBC/neutral development: _____ and _____
4. Collagen Synthesis: _______ |
|
Definition
1. Energy Metabolism: Thiamine B1, Riboflavin B2, Niacin B3, Biotin, Pantothenic Acid B5
2. Amino Acid Metabolism: Pyridoxamine B6 includes Pyridoxal and Pyridoxine.
3. RBC/neutral development: Folic Acid and Cobalamin B12
4. Collagen Synthesis: Ascorbic Acid C
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Term
Deficiencies of water-soluble vitamins:
Energy Metabolism Vitamins
1. Thiamine (B1): ____
2. Riboflavin (B2): ____
3. Niacin (B3): ____
4. Pantothenic Acid (B5): ____
5. Biotin (B7): _______ |
|
Definition
1. Thiamine (B1): Beriberi or annorexia
2. Riboflavin (B2): Ariboflavinosis
3. Niacin (B3): Pellegra
4. Pantothenic Acid (B5): Irretability and fatique
5. Biotin (B7): Conjunctivitis
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Term
Deficiencies of water-soluble vitamins:
Amino Acid Metabolism:
1. Pyridoxamine (B6): ____
RBC/neutral development
2. Folic Acid (B9): ____
3. Cobalamin (B12): _____
Collagen Synthesis
4. Ascorbic Acid (C): _____
|
|
Definition
1. Pyridoxamine (B6): seborrheic dermatitis
2. Folic Acid (B9): Impaired growth, Megaloblastic anemia
3. Cobalamin (B12): Megaloblastic anemia
4. Ascorbic Acid (C): Scurvy
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Term
Problems and deficiencies in:
Calcium: _____ and ____
Phosphorus: ____loss, ____, ____, and _____
Iron: _____ (decreased hemoglobin concention in blood) |
|
Definition
Calcium: Osteoporosis and Osteomalacia
Phosphorus: Bone loss, weakness, anorexia, and pain
Iron: Anemia (decreased hemoglobin concentration in blood) |
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Term
Name the fate of the mejor fuels in Fed State:
1. Glucose: ____ in the form of glycogen
____ for energy
2. Amino Acids: ____ synthesis
Synthesis of ____ compounds
____ for energy
3. Fats: ____ for energy
____ in the form of Triacylglycerides
Synthesis of membrane _____ |
|
Definition
1. Glucose: Stored in the form of glycogen
Oxidized for energy
2. Amino Acids: Protein synthesis
Synthesis of Nitrogen compounds
Oxidized for energy
3. Fats: Oxidized for energy
Stored in the form of Triacylglycerides
Synthesis of membrane lipids |
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Term
Know what enzymes break down which dietary fuels:
1. Carbs -> monosaccharides
Starch, lactose, and sucrose are broken down by __,___, and ___.
2. Proteins -> Amino Acids
4 enzymes break down protein: ___, ___, ___, and ___.
3. Fats (Triacylglycerols) -> FA and 2-monoglycerols
Fats are broken down in the ____ by _____ |
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Definition
1. Carbs -> monosaccharides
Starch, lactose, and sucrose are broken down by a-amylase,sucrase, and lactase.
2. Proteins -> Amino Acids
4 enzymes break down protein: Proteases, Pepsin, Trypsin, and Chymotrypsin.
3. Fats (Triacylglycerols) -> FA and 2-monoglycerols
Fats are broken down in the Pancrease by pancreatic lipase
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Term
Name the 4 lipoproteins in the blood
1.
2.
3. LDL
4. |
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Definition
Chylomicrons
VLDL
LDL
HDL |
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Term
4 Lipodproteins and their function
1. _____: made in the epithelial cells.
carries triacylglycerides in the blood
2. _____: made in the liver from glucose.
Carries triacylglycerides in blood
3. LDL: made in the blood.
BAD, contrains high concentrations of _____ and ____.
4. ____: made in liver and ____.
exchanges lipds and proteins with lipoproteins
Returns cholesterol from peripheral tissue to liver. |
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Definition
1. Chylomicrons: made in the epithelial cells.
carries triacylglycerides in the blood
2. VLDL: made in the liver from glucose.
Carries triacylglycerides in blood
3. LDL: made in the blood. (BAD)
Contrains high concentrations of cholesterol and esters.
4. HDL: made in liver and intestine.
exchanges lipds and proteins with lipoproteins
Returns cholesterol from peripheral tissue to liver. |
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Term
Explain how oxidation occurs in exerise.
Use ____ in blood or _____ in your muscles and liver to make ATP by oxidation of ___ and ___ or converting it to lactate through _____. |
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Definition
Use Glucose in blood or Glycogen in your muscles and liver to make ATP by oxidation of CO2 and H2O or converting it to lactate through Glycolysis. |
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Term
Glycogen is stored in the ____ and _____
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Definition
Glycogen is stored in the LIVER and MUSCLES |
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Term
Know the destination of Triacylglycerol in the Fed State.
TG are found in the _____ and broken down to 2-monoacylglycerols and Fatty-Acids by _____.
They interact with Bile salts to form ____.
Then interact with Epithelial cells to reform _____.
Next packaged with proteins and ___ to form _____ and are then secreted in the the blood stream.. |
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Definition
TG are found in the Intestines and broken down to Fatty-Acids and 2-monoacylglycerols by pancreatic-lipase.
They interact with Bile salts to form micelles.
Then interact with Epithelial cells to reform TG.
Next packaged with proteins and cholesterols to form Chylomicrons and are then secreted in the the blood stream. |
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Term
Know how blood glucose levels regulate the release of insulin and glucagon in the Fed State or Absorptive State
Glucose levels High:
Insulin levels ____
Glycogen levels ____
Glucagon levels ____ |
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Definition
Fed State or Absorptive State
Glucose levels High:
Insulin levels High
Glycogen levels High
Glucagon levels "Low" |
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Term
Know the differences and similarities of Hypercholesterolemia, Hyperglycemia, and Hyperlipidemia
1. Hypercholesterolemia: elevated _____ levels
____ type drugs
2.Hyperglycemia: Elevated ____ levels
______ type drugs
3. Hyperlipidemia: Elevated ____ levels
___ type drugs |
|
Definition
1. Hypercholesterolemia: elevated Cholesterol levels
Antihyperlipidemic type drugs
2.Hyperglycemia: Elevated Glucose levels
Insulin type drugs
3. Hyperlipidemia: Elevated Lipid levels
Antihyperlipidemic type drugs |
|
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Term
Know the differences and similarities of Hypercholesterolemia, Hyperglycemia, and Hyperlipidemia
Similarities:
All are ____ levels caused by specific ___ or diet.
Hypercholesterolemia and Hyperlipidemia are both cured by _____ drugs.
Differences
Hyperglycemia is cured by ___ drugs.
|
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Definition
Similarities:
All are Elevated levels caused by specific Protein or diet.
Hypercholesterolemia and Hyperlipidemia are both cured by Antihyperlipidemic drugs.
Differences
Hyperglycemia is cured by Insulin drugs. |
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Term
Post Absorptive State or Fasting state
Insulin levels _____
Glucose levels _____
Glycogen levels ______
Glucagon levels _______ |
|
Definition
Insulin levels Low
Glucose levels Low
Glycogen levels Low
Glucagon levels High |
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Term
Starved State or Prolonged Fasting
Glucose Levels _____
Glycogen Levels ______
Insulin Levels ______
Glucagon Levels _____ |
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Definition
Starved State or Prolonged Fasting
Insulin levels low
Glucose levels low
Glycogen levels low
Glucagon levels high |
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Term
In the Postabsorptive State or fasting state, which organ becomes the main exporter of glucose and ketone bodies? |
|
Definition
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Term
In the Fed State or absorptive state, which organ is the main transporter of glucose, amino acids, and Chylomicrons? |
|
Definition
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Term
Chylomicrons carry which compound to the blood? |
|
Definition
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Term
Postabsorptive State
Glucose Levels: _____
Insulin Levels: _____
Glycogen Levels: ______
Glucagon Levels: _______ |
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Definition
Glucose Levels: Low
Insulin Levels: Low
Glycogen Levels: Low
Glucagon Levels: High |
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Term
Starved State or Prolonged Fasting State
Glucose Levels: ______
Glycogen Levels: _______
Insulin Levels: ________
Glucagon Levels: ________ |
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Definition
Starved State or Prolonged Fasting State
Glucose Levels: Low
Glycogen Levels: Low
Insulin Levels: Low
Glucagon Levels: High |
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Term
Glycogen is broken down by this process in the liver during Postabsorptive State and transported to the blood |
|
Definition
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Term
Triacylglycerols are broken down by this process ______ and this enzyme _____ to form ____ and ______. |
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Definition
Triacylglycerols are broken down by this process Lipidolysis and this enzyme pancreatic lipase to form Fatty Acids and 2-monoglycerols. |
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Term
In the Postaborptive State, the liver partially oxidizes fatty acids to form ________ |
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Definition
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Term
Muscle and kidney obtain their energy from Ketone bodies by this process
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Definition
Tricarboxylic acid cycle (TCA Cycle)
Muscle, kidney, and certain other tissues derive energy from completely oxidizing ketone bodies in the tricarboxylic acid (TCA) cycle.
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Term
Gluconeogenesis occurs in the _____ and produces glucose from ____, ____, and _____ |
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Definition
Gluconeogenesis occurs in the Liver and produces glucose from Lactate, Glycerol, and amino Acids |
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Term
Ketone Bodies fuel these two parts of the body. |
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Definition
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Term
Ketone bodies are created in the liver by oxidizing _____ |
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Definition
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Term
T/F: All enzymes are proteins
T/F: All proteins are Enzymes |
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Definition
True: All enzymes are proteins
False: All proteins are enzymes
-all proteins are not enzymes |
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Term
During Starvation:
Glucose Levels _____
Fatty Acid Levels ______
Ketone Body Levels _______ |
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Definition
During Starvation:
Glucose Levels Decrease
Fatty Acid Levels Increase
Ketone Body Levels Increase |
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Term
During starvation, muscle stops using this as fuel but continunes to burn fatty acids. |
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Definition
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Term
Differences in Fasting State and Starved State
1. Brain uses ____ as an energy source (Fasting State)
2. Muscle and Kidney use ___ as an energy source (Starvation state)
3. Muscle continues to use ____ for energy, but decreases its use of _____. (Starved State).
4. Brain uses ___ as an energy source (Starved State). |
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Definition
1. Brain uses glucose as an energy source (Fasting State)
2. Muscle and Kidney use Fatty Acids as an energy source (Starvation state)
3. Muscle continues to use Fatty Acids for energy, but decreases its use of Ketone Bodies. (Starved State).
4. Brain uses Ketone Bodies as an energy source (Starved State). |
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Term
Differences in Fasting State and Starving State
1._____ is the only way to produce glucose in the Starving State.
2. Glucose is still used in the _____ and partially in the _____ in the starving state.
3. 2 Process to produce glucose in the fasting state: ____ and _____ |
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Definition
1. Gluconeogensis is the only way to produce glucose in the Starving State.
2. Glucose is still used in the RBC and partially in the brain in the starving state.
3. 2 Process to produce glucose in the fasting state: Glycogenolysis and Gluconeogenesis |
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Term
Creatinine released from the________ is proportional to muscle mass.
The amount of creatinine excreted can be used to determine amount of______ in the body.
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Definition
Creatinine Height Index measure the protein depletion from the body.
Creatinine released from the muscles is proportional to muscle mass.
The amount of creatinine excreted can be used to determine amount of muscle in the body. |
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Term
There are a total of ___ L of water in the body.
____ L in the ICF
_____ L in the ECF |
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Definition
There are a total of 40 L of water in the body.
25 L in the ICF
15 L in the ECF |
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Term
The ECF has High concentrations of these 2 eletrolytes: ____ and ____
The ICF has High Concentrations of 1 electrolyte _____ and inorganic _____ |
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Definition
The ECF has High concentrations of these 2 eletrolytes: Na+ and Cl-
The ICF has High Concentrations of 1 electrolyte K+ and inorganic Phosphate |
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Term
a. _________: measure of concentration of solutes
i. Proportional to total concentration of all dissolved molecules.
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Definition
a. Osmolality: measure of concentration of solutes
i. Proportional to total concentration of all dissolved molecules.
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Term
b. ___________: quantity of a particular substance that can be dissolved in a particular solvent |
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Definition
b. Solubility: quantity of a particular substance that can be dissolved in a particular solvent |
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Term
a. _________ Bonds:
i. Strong electronegative atom with hydrogen
b. _________ Interactions
i. Attraction: + with - Repulsion: - with – or + with +
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Definition
a. Hydrogen Bonds:
i. Strong electronegative atom with hydrogen
b. Ionic Interactions
i. Attraction: + with - Repulsion: - with – or + with +
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Term
a. _________ Interactions
i. Nonpolar molecule with polar molecules
b. __________ Reaction
i. Any 2 atoms in close proximity
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Definition
a. Hydrophobic Interactions
i. Nonpolar molecule with polar molecules
b. Van der Waals Reaction
i. Any 2 atoms in close proximity
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Term
a. ∆G (free energy change) :
Favorable or Unfavorable
i. Negative = _______
ii. Positive =______
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Definition
a. ∆G (free energy change) :
i. Negative = favorable reaction
ii. Positive = unfavorable
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Term
a. ∆H (Enthalpy change)
i. Negative: Exothermic Bonds ________ Energy ______
ii. Positive: Endothermic Bonds ________ Energy _________
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Definition
a. ∆H (Enthalpy change)
i. Negative: Exothermic Bonds Broken Energy Released
ii. Positive: Endothermic Bonds formed Energy Absorbed
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Term
a. ∆S (_______Change)
i. Measure of _______ in a system
Positive or negative?
ii. ______________ : more molecules, more randomness
__________ : less molecules, less randomness |
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Definition
a. ∆S (Entropy Change)
i. Measure of randomness in a system
ii. Positive: more molecules, more randomness
Negative: less molecules, less randomness |
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Term
1. Know the importance of pH & why and how it is regulated
a. A _______ pH wards off infections
b. Body keeps a neutral pH by use of________.
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Definition
a. A neutral pH wards off infections
b. Body keeps a neutral pH by use of buffers
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Term
Know the Equation in water for
Keq =
Kw =
Kd =___ |
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Definition
Keq = [H+][OH-] / [H2O]
Kw = [H+] [OH-]
Kd = Keq |
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Term
a. _________ in the lungs is in equilibrium with the bicarbonate buffer in the blood passing through the lungs. Breathing can dissolve CO2 and the blood is in equilibrium with the CO2. But because carbonic acid is in equilibrium with CO2, less breathing can increase the levels of carbonic acid in the blood.
Buffers work best within a range of 1 pH unit either above or below the pKa of the buffer, where the pKa is the negative log of the Ka.
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Definition
a. CO2 in the lungs is in equilibrium with the bicarbonate buffer in the blood passing through the lungs. Breathing can dissolve CO2 and the blood is in equilibrium with the CO2. But because carbonic acid is in equilibrium with CO2, less breathing can increase the levels of carbonic acid in the blood.
Buffers work best within a range of 1 pH unit either above or below the pKa of the buffer, where the pKa is the negative log of the Ka.
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Term
Enzyme that breaks down protein to amino acids |
|
Definition
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Term
Enzyme that breaks down Fat or TG |
|
Definition
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Term
4 enzymes that break down proteins are |
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Definition
4 enzymes that break down proteins are
pepsin, proteases, trypsin, chymotrypsin |
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Term
Triacylglycerides are mainly found in the _______ (organ) |
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Definition
Triacylglycerides are mainly found in the Intestines (organ) |
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Term
Triacylglycerides are packaged with proteins and cholesterols to form ________ |
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Definition
Triacylglycerides are packaged with proteins and cholesterols to form Chylomicrons |
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Term
Chylomicrons, LDL, VLDL, and HDL are all found in the blood and are 4 forms of this type of protein |
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Definition
Chylomicrons, LDL, VLDL, and HDL are all found in the blood and are 4 forms of this type of protein
Lipoprotein |
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Term
This process breaks down Ketone bodies |
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Definition
This process breaks down Ketone bodies
TCA Cycle |
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Term
Gluconeogensis occurs in which organ? |
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Definition
Gluconeogensis occurs in which organ?
Liver |
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Term
Chylomicrons are made in this type of cells |
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Definition
Chylomicrons are made in this type of cells
Epithlial Cells |
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Term
In the Red Blood Cells, Glucose in converted to this. Also occurs during excercise in the muscle. |
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Definition
In the Red Blood Cells, Glucose in converted to this. Also occurs during excercise in the muscle.
Lactate |
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Term
Ketone Bodies are formed in this organ: _____
During Fasting and Starvations, they are the primary energy source in these 2 organs. ___ and ____ |
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Definition
Ketone Bodies are formed in this organ
Liver
During Fasting and Starvations, they are the primary energy source in these 2 organs. Brain and Muscle |
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Term
Ketone Bodies can be made by partially oxidizing _____
They can also be made by amino acids because the liver can convert them to glucose or ketone bodies |
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Definition
Ketone Bodies can be made by partially oxidizing Fatty Acids
They can also be made by amino acids because the liver can convert them to glucose or ketone bodies. |
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Term
3 major Ketone bodies are |
|
Definition
3 major Ketone bodies are
1 β-hydroxybutyrate
2. acetoacetate
3. acetone |
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Term
Which enzyme is used when CO2 and H2O are converted to carbonic Acid (H2COH3)? |
|
Definition
Which enzyme is used when CO2 and H2O are converted to carbonic Acid (H2COH3)?
Carbonic Anhydrase |
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Term
Within the Red Blood Cell, what are the buffers?
____ and _____ |
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Definition
Within the Red Blood Cell, what are the buffers?
____ and _____
Hemoglobin (Hb) and Phosphate (HPO4-) |
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Term
Bicarbonate Buffer System
Decreased breathing results in:
______ dCO2
_______ carbonic acid
__________ pH
_________ O2 in blood |
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Definition
Bicarbonate Buffer System
Decreased breating results in:
Increased dCO2
decreased carbonic acid
decreased pH
decreased O2 in blood |
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Term
RESPIRATORY ACIDOSIS
High or Low: ___ PaCO2 & ____ pH
|
|
Definition
RESPIRATORY ACIDOSIS
High or Low: High PaCO2 & Low pH
*Too much CO2 creates too much Carbonic Acid |
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Term
RESPIRATORY ALKALOSIS
High or Low: ___ PaCO2 _____pH
|
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Definition
RESPIRATORY ALKALOSIS
High or Low: Low PaCO2 High pH
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Term
METABOLIC ACIDOSIS
High or Low
____ HCO3- & _____ pH
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Definition
METABOLIC ACIDOSIS
High or Low
Low HCO3- & Low pH
*metabolic are proportional to pH and Bicarbonate |
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Term
METABOLIC ALKALOSIS
High or Low
____ HCO3- & ____ pH
|
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Definition
METABOLIC ALKALOSIS
High HCO3- & High pH
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Term
Which one is an omega-3 and omega-6 fatty acid?
Linoleic _____
Linolenic ______ |
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Definition
Which one is an omega-3 and omega-6 fatty acid?
Linoleic Omega 3
Linolenic Omega 6 |
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Term
Triacylglycerides are broken down pancreatic lipase by this process
_________ |
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Definition
Triacylglycerides are broken down pancreatic lipase by this process
Lipidolysis |
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Term
Gluconeogenesis Occurs in the ______ and is the only way for your body to produce glucose in the starvation state. |
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Definition
Gluconeogenesis Occurs in the Liver and is the only way for your body to produce glucose in the starvation state. |
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Term
During the starvation state, glucose is still being used main in the ______ and partially in the brain. |
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Definition
During the starvation state, glucose is still being used main in the Red Blood Cells and partially in the brain. |
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Term
Glucose contains an aldehyde which makes it a ______ |
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Definition
Glucose contains an aldehyde which makes it a Aldohexose |
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Term
Carboxylic Acid + Alcohol = _______ |
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Definition
Carboxylic Acid + Alcohol = Ester
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Term
Carboxylic Acid + Sulfhydryl = _______ |
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Definition
Carboxylic Acid + Sulfhydryl = Thioester
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Term
Phosphoric Acid + Alcohol = __________ |
|
Definition
Phosphoric Acid + Alcohol = Phosphoester |
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Term
The product that leaves when an acid and alcohol interact is ________ |
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Definition
The product that leaves when an acid and alcohol interact is Water |
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Term
Carboxylic Acid + Amine = _______ |
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Definition
Carboxylic Acid + Amine = Amide |
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Term
Phosphoric Acid + Phosphoric Acid = _______
What by product results from this interaction? |
|
Definition
Phosphoric Acid + Phosphoric Acid = Anhydride
What by product results from this interaction?
Water |
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Term
Difference between glucose and fructose is the location of the ______ group
This makes Fructose a ______
and glucose a aldohexose |
|
Definition
Difference between glucose and fructose is the location of the Carbonyl group
This makes Fructose a ketohexose
and glucose a aldohexose |
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|
Term
Bottom or Top
alpha linkage occurs with the hydroxyl group on the _____ |
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Definition
Bottom or Top
alpha linkage occurs with the hydroxyl group on the Bottom (below the H) |
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Term
Bottom or top
Beta-linkage occurs with the hydroxyl group on the ______ |
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Definition
Bottom or top
Beta-linkage occurs with the hydroxyl group on the Top |
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|
Term
What is the term that describes: ________
Flipping the OH from the enantionmeric center
i) Change in the optical rotation that occurs in an equilibrium between two epimers (differ in 1 stereocenter).
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|
Definition
What is the term that describes: Mutarotation
Flipping the OH from the enantionmeric center
i) Change in the optical rotation that occurs in an equilibrium between two epimers (differ in 1 stereocenter). |
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Term
What is the Term?
a) ______________
i) Same chemical formula
ii) Different positions of functional groups
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Definition
What is the Term?
a) Stereoisomer
i) Same chemical formula
ii) Different positions of functional groups
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Term
What is the Term?
a) __________________
i) one of two stereoisomers
ii) mirror images of each other
iii) non-superposable
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Definition
What is the Term?
Enantiomer
i) one of two stereoisomers
ii) mirror images of each other
iii) non-superposable
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Term
a) Oxidized Sugar:
i) Oxidized at the _______ group to form an acid
Which group?
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Definition
a) Oxidized Sugar:
i) Oxidized at the aldehyde group to form an acid
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Term
i) If _______ group is reduced, changed to a deoxy sugar and replaced with( -H)
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Definition
i) If hydroxyl group is reduced, changed to a deoxy sugar and replaced with( -H)
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Term
1) Also know the difference between pyranose and furanose.
D-glucose has a ______ group
D-fructose has a ______ group
D-glucose forms glucopyranose which has a ____ membered ring
D-fructose forms fructofuranose which has a ____ membered ring
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Definition
1) Also know the difference between pyranose and furanose.
D-glucose has a Aldehyde group
D-fructose has a Ketone group
D-glucose forms glucopyranose which has a 6 membered ring
D-fructose forms fructofuranose which has a 5 membered ring |
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Term
1) Identify each class of lipids, list their functions and explain their relationships with specific diseases
a) Fatty acids:
Unsaturated has ______ bonds
Cis is (good or bad)
Trans (good or bad)
Saturated are also called _____ acids
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Definition
1) Identify each class of lipids, list their functions and explain their relationships with specific diseases
a) Fatty acids:
Unsaturated has Double bonds
Cis is (good or bad)
Trans (good or bad)
Saturated are also called stearic acids |
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Term
Linoleic and Linolenic are examples of _____ Fatty Acids that are in the (cis or trans) form.
Linolenic is also called omega-(3,6,9) fatty acid
Linoleic is also called omega-(3,6,9) fatty acid |
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Definition
Linoleic and Linolenic are examples of unsaturated Fatty Acids that are in the (cis or trans) form.
Linolenic is also called omega-(3,6,9) fatty acid
Linoleic is also called omega-(3,6,9) fatty acid |
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Term
1) Identify each class of lipids, list their functions and explain their relationships with specific diseases
Fatty Acid and Glycerol can be formed with esterification to make _______
_______ can also be oxidized to CO2 and H2O |
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Definition
1) Identify each class of lipids, list their functions and explain their relationships with specific diseases
Fatty Acid and Glycerol can be formed with esterification to make Triacylglycerols
Triacylglycerols can also be oxidized to CO2 and H2O |
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Term
1) Identify each class of lipids, list their functions and explain their relationships with specific diseases
Phospholipids are a major components of the _____ (this part of call)
They are cleaved by ______
and a Lung Surfactant |
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Definition
Phospholipids are a major components of the membrane
They are cleaved by phospholipases
and a Lung Surfactant |
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Term
1) Identify each class of lipids, list their functions and explain their relationships with specific diseases
Sphingolipids are derivatives of ____
–Sphingomyelin
–Galactocerebroside
–Ganglioside
•White matter of CNS
•Sphingolipidoses
–Tay-Sachs
–Gaucher’s
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Definition
1) Identify each class of lipids, list their functions and explain their relationships with specific diseases
Sphingolipids are derivatives of ceramide
–Sphingomyelin
–Galactocerebroside
–Ganglioside
•White matter of CNS
•Sphingolipidoses
–Tay-Sachs |
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Term
1) Identify each class of lipids, list their functions and explain their relationships with specific diseases
______ are forms of cholesterol
precursers for hormones, Vitamin D, and Bile Acids |
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Definition
Steroids are forms of cholesterol
precursers for hormones, Vitamin D, and Bile Acids |
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Term
1) Identify each class of lipids, list their functions and explain their relationships with specific diseases
______ are short-term signaling molecules
Prostaglandins (PGs)
Thromboxane A2 (TXA2)
Leukotrienes (LTs) |
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Definition
Eicosanoids are short-term signaling molecules
Prostaglandins (PGs)
Thromboxane A2 (TXA2)
Leukotrienes (LTs) |
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Term
Chapter 5
______ is a compound that has a Hydrogen that can shift places resulting in double to single bonds or opposite.
Considered same compound different structure.
One form is more reactive than the other
Example: uric acid, urate, gout |
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Definition
Chapter 5
Tautomer is a compound that has a Hydrogen that can shift places resulting in double to single bonds or opposite.
Considered same compound different structure.
One form is more reactive than the other
Example: uric acid, urate, gout |
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Term
Chapter 5
____ is a compound that has a single electron
______ exist independently within a solution |
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Definition
Chapter 5
Radical is a compound that has a single electron
Free Radical exist independently within a solution |
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Term
Chapter 5
______ are radicals within a cell that are the source for desctruction.
Very toxic, reactive, and potent.
Ex: Nitrogen Oxide radical |
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Definition
Chapter 5
Superoxides are radicals within a cell that are the source for desctruction.
Very toxic, reactive, and potent.
Ex: Nitrogen Oxide radical |
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Term
Chapter 5
Purines + Pyrimidines + _______ are all nitrogenous bases |
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Definition
Chapter 5
Purines + Pyrimidines + pyridines are all nitrogenous bases |
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Term
• Clinical correlations: understand how the chlorinated aromatic hydrocarbon environmental toxins behave in the body
____ and ____ are chlorinated aromatic hydrocarbon environmental toxins.
___ were used as herbicides in the US.
___ are formed as by product during the production of other chlorinated cmpounds and herbicides
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Definition
• Clinical correlations: understand how the chlorinated aromatic hydrocarbon environmental toxins behave in the body
DDTs and CDDs are chlorinated aromatic hydrocarbon environmental toxins.
DDT were used as herbicides in the US.
CDDs are formed as by product during the production of other chlorinated cmpounds and herbicides |
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Term
Two endocrine hormones regulate fuel storage and retrieval
_____ and _____ |
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Definition
Two endocrine hormones regulate fuel storage and retrieval
glucagon and insulin |
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Term
Chapter 2
Major carbohydrate in blood is _____ and its levels regulate the release of insulin and glucagon |
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Definition
Major carbohydrate in blood is glucose and its levels regulate the release of insulin and glucagon |
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Term
Chapter 2
Glucose can be stored in two forms in the fed state:
_____ and ____ |
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Definition
Chapter 2
Glucose can be stored in two forms in the fed state:
Triacylglycerol and Glycogen |
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Term
Chapter 2
Insulin stimulates the uptake of glucose in _____ and _____ |
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Definition
Insulin stimulates the uptake of glucose in adipose tissue and muscle |
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Term
Triacylglcerol obtains from the diet is released in the blood in the form of ______ |
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Definition
Triacylglcerol obtains from the diet is released in the blood in the form of Chylomicrons |
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Term
Chapter 2
Triacylglycerols can be made from glucose in the _____ and released as _____
_______ is the storage stie for triacylglycerols |
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Definition
Triacylglycerols can be made from glucose in the Liver and released as VLDL.
Adipose Tissue is the storage stie for triacylglycerols |
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Term
Chapter 2
___ and ____ use glucose as a primary energy source under normal conditions |
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Definition
Brain and Red Blood Cells use glucose as a primary energy source under normal conditions |
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Term
Amino Acids in the diet are used to form _____ and nitrogen-containing molecules and an energy source. |
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Definition
Amino Acids in the diet are used to form Protein and nitrogen-containing molecules and an energy source. |
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Term
After a high-carb meal, your liver and skeletal muscles use ____ as their major fuel |
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Definition
After a high-carb meal, your liver and skeletal muscles use glucose as their major fuel |
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Term
During fasting, ______ is released from the pancrease. |
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Definition
During fasting, Glucoagon is released from the pancrease. |
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Term
In the fasting state, the glucagon released from the pancreas signals to the _____ to release more glucose in to circulation. |
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Definition
In the fasting state, the glucagon released from the pancreas signals to the Liver to release more glucose in to circulation. |
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Term
Ketone bodies are made from the _____ . |
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Definition
Ketone bodies are made from the Liver . |
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Term
Glucagon also signals the fat cells to degrade triacylglycerol into fatty acids and glycerol for ______. |
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Definition
Glucagon also signals the fat cells to degrade triacylglycerol into fatty acids and glycerol for gluconeogenesis. |
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Term
The three substrates for gluconeogenesis are lactate, _____, and glycerol. |
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Definition
The three substrates for gluconeogenesis are lactate, Amino Acids, and glycerol. |
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Term
In starvation, the brain adapt to using ketone bodies for energy. This results in a reduced rate of muscle protein degradation to provide more precursors for this process ______. |
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Definition
In starvation, the brain adapt to using ketone bodies for energy. This results in a reduced rate of muscle protein degradation to provide more precursors for this process Gluconeogenesis. |
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Term
After 24 hours of fasting, _______ occuring in the liver,will be the major source of glucose. |
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Definition
After 24 hours of fasting, Gluconeogenesis occuring in the liver,will be the major source of glucose. |
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Term
Patient stops taking insulin for 5 days and results in elevated glucose levels and ketone bodies. The ketone bodies are elevated by of the ______. |
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Definition
Patient stops taking insulin for 5 days and results in elevated glucose levels and ketone bodies. The ketone bodies are elevated by of the glucose. |
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Term
You can increase the carbonic acid concetration in your body or lower your pH by ______ breathing. |
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Definition
You can increase the carbonic acid concetration in your body or lower your pH by reducing breathing. |
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Term
Bicarbonate Buffer system in the body occurs in the ECF or ICF?
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Definition
Bicarbonate Buffer system in the body occurs in the ECF or ICF?
ECF |
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Term
Linoleic and Linolenic are from _____ oils (walnut) |
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Definition
Linoleic and Linolenic are from Plant oils (walnut) |
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Term
•EPA (eicosapentaenoic acid) &
DHA (docosahexaenoic acid)
are from_____ oil
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Definition
•EPA (eicosapentaenoic acid) &
DHA (docosahexaenoic acid)
are from Fish oil |
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Term
•Polyunsaturated
–Help maintain _____ of cellular membranes
–Precursors for arachidonic acid (_____acid) from which the eicosanoids are derived
–Prevent platelet aggregation
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Definition
•Polyunsaturated
–Help maintain fluidity of cellular membranes
–Precursors for arachidonic acid (linoleic acid) from which the eicosanoids are derived
–Prevent platelet aggregation
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Term
Essential Fatty Acids
•Deficiency: dermatitis, ___ ___ ___, hair loss
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Definition
Essential Fatty Acids
•Deficiency: dermatitis, slow wound healing, hair loss |
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Term
Monosaccharides
Glucose: ___ sugar, energy for most cells
Galactose: converted to glucose and _____
Fructose: _____ sugar, converted to glucose and metabolized |
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Definition
Monosaccharides
Glucose: blood sugar, energy for most cells
Lactose: converted to glucose and metabolized
Fructose: Fruit sugar, converted to glucose and metabolized
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Term
Disaccharides
Sucrose: ___ sugar, digested to glucose and ____
Lactose: ___ sugar, digested to glucose and ___ ; important in ____ nutrition
Maltose: ___ sugar, product of ____ digestion, digested to glucose and _____ |
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Definition
Disaccharides
Sucrose: Cane sugar, digested to glucose and Fructose
Lactose: Milk sugar, digested to glucose and Galactose ; important in infant nutrition
Maltose: Malt sugar, product of starch digestion, digested to glucose and glucose |
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Term
Polysaccharides
_____ : structural polysaccharide of plants
_____: Energy storage in plant cells
______: energy storage in animal cells; (liver, muscle, brain, uterus, vagina) |
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Definition
Polysaccharides
Cellulose : structural polysaccharide of plants
Starch: Energy storage in plant cells
Glycogen: energy storage in animal cells; (liver, muscle, brain, uterus, vagina) |
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Term
3 Conjugated Carbohydrates are ____, ____, and ___. |
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Definition
3 Conjugated Carbohydrates are Glycolipid, glycoprotein, and Proteoglycan. |
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Term
Conjugated Carbohydrates
_____ and _____ are components of the cell surface coat .
____ function is cell adhesion; lubrication; supportive filler of some tissues and organs
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Definition
Conjugated Carbohydrates
Glycoprotein and Glycolipid are components of the cell surface coat .
Proteoglycan function is cell adhesion; lubrication; supportive filler of some tissues and organs
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Term
Body stores the most fuel in the form of ______ > Protein > Glycogen in your ____ and ____ |
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Definition
Body stores the most fuel in the form of Triglycerides > Protein > Glycogen in your Muscle and Liver. |
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