Term
What is the deltaG for PFK?
What is the deltaG' for PFK? |
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Definition
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Term
What is the deltaG for Hexokinase?
What is the deltaG' for Hexokinase? |
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Definition
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Term
What is the deltaG for PK?
What is the deltaG' for PK? |
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Definition
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Term
| What are points of regulation? |
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Definition
| Points with the most negative free energy. |
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Term
| What three enzymes function with large negative deltaG's? |
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Definition
| Hexokinase, Phosphfructokinase, and Pyruvate kinase |
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Term
What is an inhibitor of Hexokinase?
What is an activator of Hexokinase? |
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Definition
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Term
What is an inhibitor of PFK?
What is an activator of PFK? |
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Definition
ATP, citrate, and PEP
All of them. |
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Term
What is an inhibitor of Pyruvate kinase?
What is an activator of Pyruvate kinase? |
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Definition
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Term
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Definition
| By the hydrolysis of lactose |
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Term
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Definition
| the digestion of polysaccharides and glycoproteins. |
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Term
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Definition
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Term
| What does the Phosphopentose pathway produce? |
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Definition
| NADPH and ribose-5-phosphate |
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Term
| What are the three parts of the Phosphopentose pathway? |
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Definition
| Oxidation, isomeriaztion and epimeriation, and a series of C-C bond cleavage and formations. |
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Term
| What is the produce of phosphogluconate dehydrogenase? |
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Definition
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Term
| What does trasketolase do? |
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Definition
| It transfers C2 units requiring enzymes like pyruvate dehydrogenase. |
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Term
| What does Transaldolase do? |
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Definition
| It transfers C3 units via Schiff's base with an active lysine group. |
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Term
| What controls NADPH production and this the flux through the pathway? |
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Definition
| glucose-6-phosphate dehydrogenase (G6PD) |
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Term
| What is NADPH needed for? |
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Definition
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Term
| What is glutathione required for? |
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Definition
| Erythrocyte integrity, prevents NADPH levels from dropping, and something about hemolytic anemia |
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Term
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Definition
| The conversion of lactate, pyruvate, glycerol, and amino acids to glucose. |
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Term
| What is the starting material for gluconeogenisis? |
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Definition
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Term
| Where do most precursors for Gluconeogeneis enter? |
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Definition
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Term
| What three steps are different in gluconeogensis vs glycolysis? |
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Definition
| Pyruvate to PEP, fructose-1,6- bisphosphate to fructose-6-phosphate, and glucose-6-phosphate to glucose. |
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Term
| What does the malate pathway transport and where does it transport them to? |
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Definition
| It transfers reducing equivalents from the mitochondria into the cytosol. And NADH is needed for gluconeogensis. |
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Term
| Low blood glucose leads to gluconeogensis by which steps? |
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Definition
| Increased glucagen secretion, increased cAMP, increased enzyme phosphorylation, the activation of FDPase-2 and inactivation of PFK-2, decreased F2+6P, and the inhibition of PFK and activation of FBPase |
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Term
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Definition
| Acts both catabolically and anabolically |
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Term
| What is the Citric Acid (in all its glory). |
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Definition
3NAD+ + FAD + GDP + Pi + acetyl-CoA + 2H20
YIELDS
3NADH + FADH2 + GTP + CoA + 2CO2 + 3H+ |
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Term
| What is the Pathway overview of Glucose Catabolism? |
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Definition
Glucose + 2NAD+ + 2ADP + 2Pi ->
2NADH+ + 2Pyruvate + 2ATP + 2H2O + 4H+ |
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Term
| What is the rate limiting step in Glycolysis? |
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Definition
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