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Biochemistry - Enzymes
Enzyme Classification
23
Biology
Undergraduate 3
10/16/2006

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Term
Dehydrogenase
Definition
oxidizes substrate using cofactors as electron acceptor or donor (pyruvate dehydrogenase)
Term
reductase
Definition
adds electrons from some reduced cofactor (enoyl ACP reductase)
Term
kinase
Definition
phosphorylates substrate (hexokinase)
Term
hydrolases
Definition
uses water to cleave a molecule
Term
phosphatase
Definition
hydrolyzes phosphate esters (glucose-6-phosphatase)
Term
Esterase (lipase)
Definition
hydrolyzes esters (those that act on lipid esters are lipases) (lipprotein lipase)
Term
Thioesterases
Definition
hydrolyzes thioesters
Term
thiolase
Definition
uses thiol to assist in forming thioester (B-ketothiolase)
Term
isomerases
Definition
interconversions of isomers (example aldose to ketose)(triose phosphate isomerase)
Term
mutase
Definition
shifting groups from one part of molecule to another (phosphoglucomutase)
Term
carboxylase
Definition
adds carboxyl group (pyruvate carboxylase)
Term
Decarboxylase
Definition
removes carboxyl group (pyruvate decarboxylase)
Term
oxidases
Definition
uses molecular oxygen as electron acceptor (cytochrome c oxidase)
Term
hydroxylase
Definition
adds hydroxyl group (steroid hydroxylases)
Term
Transferase
Definition
transfers chemical group from one molecule to another or within same molecule (fatty acyl transferase)
Term
Hydrase (hydratase)
Definition
adds water to double bond (enoyl CoA hydrase)
Term
Dehydrase (dehydratase)
Definition
removes water (B-hydroxyacyl ACP dehydratase) (when making enol, enolase)
Term
Lyase
Definition
splits a molecule often with electronic rearrangement but no water involvement (citrate lyase)
Term
Ligase
Definition
creates a new chemical bond joining two molecules with electronic rearrangement and no water involvement
Term
Synthetase
Definition
synthesizes product using nucleotide triphosphate (ATP) as substrate (fatty acyl CoA synthetase)
Term
Synthase
Definition
synthesizes product without ATP requirement (HMGCoA synthase)
Term
Phosphorylase
Definition
cleaves bond with incorporation of phosphate into the product (glycogen phosphorylase)
Term
Pyrophosphorylase
Definition
cleaves bond yielding pyrophosphate as one of the product (UDPG pyrophosphorylase)
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