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Biochem Test 3 Enzyme Mechanisms
N/A
9
Biochemistry
Undergraduate 3
11/10/2014

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Term
Enzymes
Definition
lower the activation energy of the reaction
Term
Things enzymes do to accelerate rates
Definition
Acid/Base catalysis
Covalent Catalysis
Metal Ion catalysis
Orient reacting groups favorably
Ground State destabilization
Remote binding of groups
Transition state stabilization (Binding)
Term
Catalytic triad
Definition
Asp
His
Ser
Term
Active site is often complementary to the
Definition
transition state of the reaction
Term
Transition State binding and catalysis lowers
Definition
delta G
Term
HIV protease inhibitors
Definition
Saquinavir
Ritonavir
Term
_____ orientation in the active site is important
Definition
substrate
Term
Protease inhibitor
Definition
sarin
chymotrypsin
Term
Thymidylate Synthase inhibitor
Definition
fDUMP
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