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Pierce'a Biochem Flashcards
CSULB's Patrick Pierce's Biochem Test
51
Chemistry
Undergraduate 1
04/29/2014

Additional Chemistry Flashcards

 


 

Cards

Term
Proteins(and uses)
Definition

Polymers of amino acids 

  • structure
  • transport
  • storage
  • enzymes
  • hormones
  • protection
Term

Amino Acid

  •  Properties?
Definition

organic compound with amino group, carboxyl group and unique side group

  • form crystals
  • high melting points
  • hydrophyllic
  • in soluble in hydrocarbon solvents
Term
Glycine
Definition

Gly

Side group: H

Nonpolar (Hydrophobic)

Term
Valine
Definition

Val

Side Group: Isopropyl group

Nonpolar (hydrophobic)

Term
Leucine
Definition

Leu

Side Group: Isobutyl

Nonpolar (hydrophobic)

Term
Isoleucine
Definition

Ile

Side Group: Sec-butyl

Nonpolar (hydrophobic)

Term
Alanine
Definition

Ala

Side Group: Methyl

Nonpolar (hydrophobic)

Term
Phenylalanine
Definition

Phe

Side Group: methyl then phenyl group

Nonpolar (hydrophobic)

Term
Tyrosine
Definition

Tyr

Side Group: methyl then 4-phenol

Polar (hydrophyllic)

Term
Serine
Definition

Ser

Side Group: methanol 

Polar (hydrophyllic)

Term
Cysteine
Definition

Cys

Side Group: methyl then thiol (eh)

Polar (hydrophyllic)

 

Term
Lycine
Definition

Lys

Side Group: butylamine

Basic

Term

Aspartate (also known as)

 

Definition

Aspartic Acid

Asp

Side Group: methyl then COO^-

Acidic

Term
Glutamate (also known as)
Definition

Glutamic Acid

Glu

Side Group: ethyl then COO^-

Acidic

Term
Asparagine
Definition

Asn

Side Group: methyl then CONH2

Polar (hydrophyllic)

Term
Glutamine
Definition

Gln

Side Group: ethyl then CONH2

Polar (hydrophyllic)

Term

Zwitterion

  • when in Acidic and basic solutions?
Definition

Has charged -NH3^+ and COO^- groups

  • forms when -NH2 and COOH groups ionize in H-OH
  • Low pH= -COO^- accept H+
  • High pH= NH3^+ lose H+
Term

Peptide Bond

  1. Also known as?
  2. # of units
  3. Locate N-Terminus and C-Terminus
Definition
  1. Amide bond
  2. Carboxyl group of one amino acid reacts with amino group of another amino acid (loss of H-OH)
  3. N-terminus on the left and C-terminus on right

 

Term

Distinguish between 

  • Protein
  • Peptide
  • Amino Acid Residue
  • Polypeptide
Definition

Peptides- short length amino acid polymer

Polypeptide-less than 50 amino acids

Protein-more than 50 amino acids

amino acid residue- amino acid that is part of a polymer

Term
Lipids
Definition

Naturally occuring compounds that are insoluble in water

Dissolved in nonpolar solvents like ethers and chloroform 

Term
Steroids
Definition
Steroid nucleus with four fused carbon chains and no fatty acids
Term
Saturated fatty acids
Definition

Lauric, Myristic, Palmitic, and Stearic Acid.

 

Term
Unsaturated fatty acids
Definition
  • fatty acids with 1+ double bonds consisting of cis- or trans- isomers
  • Normally liquids at room temperature
  • has irregular shape
Term
Essential fatty acids
Definition
Polyunsaturated fatty acids that are not synthesized in the human body and must be obtained through food.
Term
Prostaglandins
Definition
An eicosanoid that is composed of arachidonic acids with a 5-carbon ring and known for many biological effects such as lowering blood pressure and stimulate uterine contractions
Term
Leukotrienes
Definition
An eicosanoid without a 5-carbon chain discovered from leukocytes
Term
Waxes
Definition
The simplest fatty acid esters with alcohols of 24-36 carbons and 16-36 Carbons on the acid.
Term
Triacyglycerols
Definition

TAGs

Triesters of glycerol containing three fatty acids making them hydrophobic molecules without ionic charges.

Term
Fats
Definition
Solid Triacyglycerols composed of mainly saturated fatty acids and solids at room temperature.
Term
Oils
Definition
Liquid Triacyglycerols mainly composed of unsaturated fatty acids with cis double bonds making them harder to fit together to form a solid
Term
Hydrogenation in Triacyglycerols
Definition
Hydrogenation occurs in unsaturated fatty acids resulting in some turning into single bonds but some from cis into trans double bonds resulting in waxy solids such as margerine.
Term
Acid Hydrolysis of Triacyglycerols
Definition
Splitting triacyglycerols in the presence of strong acids or digestive enzymes such as lipases to for mglycerol and 3 fatty acids
Term
Base Hydrolysis of TAGs
Definition
Saponification of a TAG resulting in a glycerol and salts of fatty acids(Soaps)
Term
Soap
Definition
Salts of fatty acids formed from saponification of saturated fatty acids.
Term
Micelle
Definition
A spherical cluster formed through aggregation of soaps and detergents resulting in its hydrophillic ends at the surface and hydrophobic heads at the center.
Term
Glycerophospholipid
Definition
A polar phospholipid with a glycerol derivative, 2 fatty acids, and a polar phosphate group/amino alcohol
Term
Choline
Definition

An amino alcohol consisting of 

HO-CH2-CH2-N-(CH3)3

Term
Ethanolamine
Definition

An amino alcohol consisting of

HO-CH2-CH2-NH3+

Term
Serine
Definition

An amino alcohol consisting of

HO-CH2-CHNCOO-

Term
Phosphatidylcholine
Definition

Lecithin

  • A glycerophospholipid with the amino alcohol choline
  • an emulsifying agent that keeps nonpolar liquids within a solution
  • Added in foods to keep oils from separating out
Term
Cephalin
Definition

Phosphatidylthanolamine

A glycerophospholipid with an ethanolamine amino acid and sometimes serine.

Term
Sphingomyelin
Definition
  • A polar phospholipid AND sphingolipid characterized by a sphingosine derivative with a polar phosphate/amino alcohol at C1, and a fatty acid connected by an amide bond at C2
  • Major component of the myelin sheath and present in brain tissue
Term
Glycolipid
Definition
  • A polar sphingolipid with a sphingosine derivative and monosaccharide at C1
  • Carobohydrate group serves as receptors in cells to recognize other cells, pathogens, drugs, and chemical messengers
Term
Cerebroside
Definition

"Brain cell"

A glycolipid connected to C1 of a D-Galactose monosaccharide prevalently in nerve cells of the brain

Term
Phospholipids and Glycolipids
Definition
Serve as membrane bilayers Using polar heads and nonpolar tails to separate the interior of cells from the environment
Term
Eicosanoids
Definition

"local hormones'

A group of compounds derived from arachadonic acid functioned as short-lived chemical messengers

Term
Cholesterol (characteristics)
Definition
  • A steroid in the body characterized by its hydroxyl group at C3 of its sterid nucleus
  • obtained from meat, eggs and milk
  • synthesized in the liver
  • needed in cell membranes, brain and nerve tissue, steroid hormones and vitamin D
  • clogs arteries at high levels
  • usually measured at mg/dL
Term
Cholesterol(main functions)
Definition
  1. A component of cell membranes
  2. starting material to synthesize other steroids
Term

Cholesterol

in a cell membrane

Definition
A rigid, flat, hydrophobic molecule (aside from its hydroxy group) distributed among phospholipids' hydrophobic tail to maintain membrane structure
Term
Bile Salts
Definition
Produced in the liver, stored in the gallbladder, and emptied into the intestine to emulsify lipids-break down lipid globules to be more easily hydrolized
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