Term
List secondary structures of DNA binding proteins
"super secondary structures" |
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Definition
1. Helix-turn-helix
2. Helix-Loop-helix
3.Leucine Zipper
4. Zinc finger |
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Term
Describe what DNA binding proteins tend to have:
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Definition
-2 fold axis of symmetry and often form dimers
-very specific DNA binding via noncovalent interactions between amino acids and edges of nucleotide base pairs along the major groove |
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Term
Meselson-Stahl Experiment |
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Definition
-No longer stationary DNA
-DNA replication occurs in specific number or nucleoid compartments called replication factories- which are driven by energy pumps |
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Term
What are the basic steps in prokaryotic DNA synthesis |
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Definition
-Dna unwinding Helicases-ATP req enzyme that catalyze the unwinding of duplex DNA
-(SSB) Single stranded binding protein- protects single strand DNA segments
-Topoisomerases- work ahead of the replication form to relieve torque |
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