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The nucleotide sequence of DNA is which level of structure? |
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What level of structure is not present in nucleic acids? |
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The double helix of DNA is which level of structure? |
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What distinguishes nucleotides from nucleosides? |
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Definition
Nucleosides lack the phosphate group |
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What is the most common modification to nucleic acid bases? |
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Definition
reduction of a carbonyl to an alcohol |
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Term
Phosphate is important in nucleic acids because it can form a phosphodiester bond? TRUE/FALSE |
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Which base is not found in RNA? |
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Which nucleobases are purines? |
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The fundamental differences between RNA and DNA are: |
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Which of the following groups are not found in nucleosides? phosphates; purines; pyrimidines; sugars |
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The backbone of nucleic acids consists of: |
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Definition
a phosphodiester bond between the 3' and 5' hydroxyl groups of neighboring sugars |
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The oligonucleotide AGGUCCAUUGAAp, is best described as... |
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Definition
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Histones are proteins that... |
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Definition
are frequently associated with eukaryotic DNA |
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What is the dominant form of DNA? |
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Definition
tends to occur in alternating purine-pyrimidine sequences. |
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Topisomerases are associated with... |
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Which of the following RNAs is the least abundant in a typical cell? |
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tRNA bonds to amino acids in the course of protein synthesis. TRUE/FALSE |
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Definition
found in snurps; is involved in removing introns from the RNA; first shown to have catalytic activity |
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Duplication process of DNA is called... |
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Definition
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Flow of genetic information is RNA>>>DNA in: |
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Semiconservative replication implies that... |
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Definition
each of the new double stranded DNA molecules contains one of the original intact strands and one completely new strand. |
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Term
How do origins of replication differ in eukaryotes and prokaryotes? |
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Definition
eukaryotes have several origins, while prokaryotes typically have one |
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The direction of synthesis of DNA is... |
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Definition
from the 5' to the 3' end on both strands |
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Term
An important process in the synthesis of new DNA is... |
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Definition
proofreading and repair; unwinding of the double helix; protection of single-stranded regions from nuclease action |
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Term
When the synthesis of new DNA is directed by an original template DNA molecule... |
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Definition
two DNA molecules are formed, each with one new strand and one strand from the original |
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Term
Which is NOT a function of DNA polymerase 3? polymerization; ligating the final products; proofreading; clamping on to the template |
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Definition
ligating the final products |
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Term
The following enzyme is responsible for the bulk of DNA synthesis during replication? |
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Definition
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The universal features of DNA replication include: |
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Definition
release of PPi from a nucleoside triphosphate; synthesis from the 5' end to the 3' end; base pairing of a A to T and G to C; use of a primer |
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Term
What function does DNA polymerase 3 lack? |
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Definition
5' to 3' exonuclease activity |
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