Term
The bond linking a fatty acid to conenzyme A is... |
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Definition
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The carrier molecule which transports fatty acids through the inner mitochondrial membrane is... |
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In beta-oxidation of fatty acids, initiation occurs at the methyl end of the fatty acid...TRUE/FALSE |
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Definition
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Term
At the beginning of catabolism, the activated fatty acid has a ____ bond. |
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Term
Where in the cell does beta-oxidation occur? |
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A special carrier is needed to get fatty acids into the mitochondria, since an acyl-CoA cannot cross the outer mitochondrial membrane...TRUE/FALSE |
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Definition
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Term
What best describes carnitine? |
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Definition
It transports fatty acids across the inner mitochondrial membrane. |
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Term
The first three reactions of the beta-oxidation cycle of fatty acids produce... |
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Definition
one each of NADH and FADH2 |
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Term
What is not a product of the activation of fatty acids? |
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Definition
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Term
Fatty acid catabolism is called beta-oxidation, since the second (beta) carbon from the carboxyl group is the site of oxidation (cleavage). TRUE/FALSE |
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Definition
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Term
What is the order of reactions involved in beta-oxidation of fatty acids? |
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Definition
1)Formation of a C-C double bond 2)Hydration of a double bond 3)Oxidation of an alcohol 4)Cleavage of acetyl-CoA from the fatty acid 1) |
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Term
Acetyl-CoA requires 8 cycles of beta-oxidation to produce palmitic acid, with 16 carbons...TRUE/FALSE |
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Definition
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Term
The processing of one molecule of stearic acid (18 carbons) by beta-oxidation requires... |
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Definition
8 cycles of beta-oxidation and produces 9 molecules of acetyl-CoA |
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Term
How many NAD+ are reduced in the degradation of palmitoyl-CoA to form 8 molecules of acetyl-CoA? |
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Definition
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Term
What vitamin/cofactor is used in fatty acid biosynthesis? |
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Definition
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Term
Lipids yield more ATP than sugars because? |
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Definition
They have more carbon atoms than sugars, thus producing more acetyl-CoA |
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Term
As a result of the beta-oxidation of fats, compared to oxidation of sugars, fatty acids produce more metabolic water during oxidative phosphorylation. TRUE/FALSE |
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Definition
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Term
Fatty acids are advantageous forms of energy storage because... |
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Definition
they contain more carbons than carbohydrates, their hydrophobicity allows close packing and do not require water for transport, and contain more energy than sugars |
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Term
In the catabolism of fatty acids with uneven numbers of carbon atoms, intermediates are converted to ___ before the final product of ___. |
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Definition
propionyl-CoA; succinyl-CoA |
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Term
The beta-oxidation of fatty acids with an odd number of carbons requires conversion to pyruvate before entering the citric acid cycle. TRUE/FALSE |
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Definition
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Term
The cis double bonds of fatty acids react well with the EH enzyme. TRUE/FALSE |
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Definition
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Term
The b-oxidation of unsaturated fatty acids requires additional enzymes to isomerize the double bonds. TRUE/FALSE |
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Definition
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Term
The unsaturated fatty acids that are intermediates in the beta-oxidation cycle must have what orientation around the double bond? |
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Definition
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Term
Isomerization of the double bonds of polyunsaturated fatty acids involves both: (i) a cis-trans isomerization; and (ii) changing the position of the double bonds. TRUE/FALSE |
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Definition
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Term
Where in the cell does fatty acid synthesis occur? |
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Definition
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Term
Reduction reactions during fatty acid synthesis utilize... |
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Definition
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Term
Reduction reactions during fatty acid synthesis utilize... |
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Definition
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Term
NADPH is required for anabolism of fatty acids and NOT for catabolism. TRUE/FALSE |
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Definition
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Term
Synthesis of fatty acids is simply the reverse of the beta-oxidation cycle. TRUE/FALSE |
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Definition
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Term
During fatty acid synthesis, the growing fatty acid is always bound to a protein. TRUE/FALSE |
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Definition
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Term
The committed step (Rate-limiting) in cholesterol biosynthesis is catalyzed by... |
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