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Biochem block 3, wk 1- Cholesterol transport
Med school biochem
17
Biochemistry
Graduate
10/20/2010

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Cards

Term
What Apo proteins do chylomicrons contain when initially made
Definition
Apo B-48 and apo A
Term
what apo proteins do chylomicrons acquire from HDL
Definition
apo C-II and apo E
Term
apo A-1
Definition
{A}ctivates LCAT
Term
apo B-100
Definition
{B}inds to LDL receptor, mediates VLDL secretion
Term
Apo C-II
Definition
{C}ofactor for lipoprotein lipase
Term
Apo B-48
Definition
Mediates chylomicron secretion
Term
Apo E
Definition
mediates {E}xtra (remnant) uptake
Term
What apo proteins do VLDL's contain
Definition
apo B-100, apo C-II, and apo E
Term
what apo proteins do IDL contain
Definition
Apo B-100, APo C-II, apo E
Term
what apo proteins does LDL have
Definition
apo B-100
Term
what apo proteins does HDL have
Definition
apo A-1, apo C-II, apo E
Term
PLTP
Definition
puts phospholipids and cholesterol into HDL
Term
CETP
Definition
takes cholest esters out of HDL
Term
ACAT
Definition
inside cells, esterfies cholesterol for storage
Term
LCAT
Definition
outside cells, esterfies cholesterol inside lipoproteins
Term
Fibrates
Definition
Drugs that target PPARalpha; They lower triglyc lvls and incr HDL
Term
Thiazolidinediones
Definition
drugs that lower glucose; enhance insulin sensitivity; incr SR-B1 recepts (these are involved in reverse cholesterol synth)
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