Shared Flashcard Set

Details

BIOC Glycolysis
glycolysis pathway enzymes
26
Biochemistry
Undergraduate 2
11/26/2013

Additional Biochemistry Flashcards

 


 

Cards

Term
Name the enzyme required...

glucuse - glucose 6 phosphate
Definition
hexokinase
Term
Name the enzyme required...

glucose-6-phosphate to fructose-6-phosphate
Definition
phosphohexose isomerase
Term
Name the enzyme required...

fructose-6-phosphate to fructose-1,6-biphosphate
Definition
phosphofruktokinase-1
Term
Name the reactant & product this enzyme is involved with

aldolase
Definition
fructose-1,6-biphosphate is converted to glyceraldehyde-3-phosphate and dihyxydroxyacetone phosphate
Term
Name the reactant & product this enzyme is involved with

Triose phosphate isomerase
Definition
Converts dihyxrodyacetone phosphate to glyceraldehyde-3-phosphate
Term
What step involves the removal of water?
Definition
Dehydration of 2-phosphoglycerate to form phosphoenol pyruvate
Term
Name the reactant & product this enzyme is involved with

enolase
Definition
Dehydration of 2-phosphoglycerate to form phosphoenol pyruvate
Term
Name the reactant & product this enzyme is involved with

Glyceraldehyde-3-phosphate dehydrogenase
Definition
Converts glyceraldehyde-3-phosphate to 1,3-biphosphoglycerate
Term
Name the reactant & product this enzyme is involved with

pyruvate kinase
Definition
Converts phosphoenol pyruvate to enol pyrovate, which is converted to keto pyruvate
Term
What do mutases do?
Definition
Catalyze reactions that involve moving a functional group from on location in a molecule to another
Term
What type of phosphorylation occurs in glycolysis?
Definition
Substrate Level Phosphorylation
Term
Which tautomer of pyruvate is initially produced?
Definition
The enol form.
(This will rapidly undergo tautomerization to form the keto form)
Term
What cofactors are required in the final step of glycolysis?
Definition
MG2+ and K+
Term
True or False
Glucose enters the cell by passive diffusion
Definition
False

Glucose enters the cell in a reaction catalyzed by GLUTs
Term
What are GLUTs?
Definition
Glucose transporter proteins
Term
True or False

Glucose is the ONLY mechanism that can provide energy in anaerobic conditions
Definition
True
Term
What is the function of glutamate in glycolysis?
Definition
A glutamate residue of the phosphohexose isomerase enzyme acts as first a general base and then a general acid when an ene-diol intermediate is formed prior to forming fructose-6-phosphate
Term
How does aldolase function?
Definition
Fructose-1,6-biphoshate ring structures opens to take on the linear form. Aldolase cuts between C3 & C4
Term
What enzyme converts pyruvate to lactate under anaerobic conditions?
Definition
lactate dehydrogenase
Term
What is the reducing agent in the conversion of pyruvate to lactate?
Definition
NADH is the reducing agent, it is oxidized to NAD+
Term
What is gluconeogenesis?
Definition
The recycling of lactate back to glucose by the liver
Term
What do microorganisms convert pyruvate to in anaerobic conditions?
Definition
acetaldehyde and then to ethanol
Term
What enzyme convrts pyruvate to acetylaldehyde?
Definition
pyruvate decarboxylase
Term
What enzyme converts acetylaldehyde to ethanol?
Definition
alcohol dehydrogenase
Term
Why can't animals convert pyruvate to ethanol under anaerobic conditions?
Definition
They don't have pyruvate decarboxylase. They do have alcohol dehydrogenase but the reaction proceeds only in reverse (ethanol to acetaldehde)
Term
Is glucose a polar or non-polar molecule?
Definition
Polar
Supporting users have an ad free experience!