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bio251 exam 2
made from lecture notes
90
Physiology
Undergraduate 2
10/05/2009

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Term
central nervous system
Definition
brain and spinal cord
Term
peripheral nervous system
Definition
afferent and efferent divisions
Term
afferent neurons
Definition
send information from the body to the central nervous system. have sensory receptors. axon terminals in CNS.
Term
efferent neurons
Definition
send information from the central nervous system to the body. cell body in CNS. axon terminals in effector organs.
Term
somatic nervous system
Definition
responsible for voluntary muscular movements and reception of external stimulus. associated with efferent neurons.
Term
autonomic nervous system
Definition
responsible for maintaining body via unconscious actions such as heart beating, breathing ect. broken up into parasympathetic and sympathetic nervous systems.
Term
sympathetic nervous system
Definition
more active during stress. responsible for fight or flight reaction.
Term
parasympathetic nervous system
Definition
works in the opposite way the sympathetic does. "rest and digest"
Term
interneurons
Definition
within CNS. connect afferent to efferent. connect other interneurons. responsible for "mind" thoughts, emotion, motivation. 99% of all neurons are interneurons.
Term
brain stem
Definition
connecting link between brain and spinal cord. cardiovascular, respiratory and digestive control. muscle reflexes; posture and equilibrium. receives and analyses info from spinal cord. sleep/wake cycle control
Term
cerebellum
Definition
maintains balance. enhancement of muscle tone. coordination of voluntary muscle activity.
Term
hypothalamus
Definition
regulation of homeostasis. body temp, thirst/urine, food intake, uterine contraction and milk production. link between nervous and endocrine system. involved in emotion and basic behavior patterns.
Term
thalamus
Definition
filters all info going into cerebral cortex. crude awareness of sensation. some degree of consciousness. role in motor control.
Term
cerebrum
Definition
basal nuclei and cerebral cortex
Term
basal nuclei
Definition
inhibits muscle tone. coordination of slow maintained movement. suppression of useless movement.
Term
cerebral cortex
Definition
sensory perception. voluntary control of movement. language. personality. consciousness and thinking/memory mental events.
Term
limbic system
Definition
not separate structure. includes; cerebral cortex, basal nuclei, thalamus, hypothalamus. involved in generating emotion.
Term
language and speech
Definition
cerebral cortex
Term
emotions
Definition
generated by limbic system, attaches feelings to programs of the brainstem. have some emotional recognition at birth and develops as life continues.
Term
memory
Definition
short term and long term
Term
short term memory
Definition
frontal lobes of cortex. rapid changes in nerve connections
Term
long term memory
Definition
limbic system. requires new connections among neurons.
Term
glial cells
Definition
90% of CNS cells, only 50% of brain volume. to not initiate or conduct nerve impulses. support CNS physically, metabolically and homeostatically.
Term
Blood Brain Barrier
Definition
shields brain from harmful blood changes. brain capillaries have tight junctions so no material can pass. only small lipid soluble substances can pass. all other molecules require carrier protein. part of hypothalamus no barrier so hormone levels in blood can be monitored.
Term
brain and O2 and glucose
Definition
brain can only make atp from glucose in the presence of O2. 4-5 min no O2=dead 10-15 min no glucose=brain damage and death.
Term
spinal cord structure
Definition
whole cord- 31 pairs of nerves. gray matter=cell bodies, dendrites, short interneurons, glial cells. white matter=mylenated axons organized into bundles, ascending and descending.
Term
spinal cord function
Definition
carrier and supports neurons between brain and body. simple spinal reflex.
Term
visceral afferent
Definition
subconscious information sent from the internal viscera to CNS
Term
sensory afferent
Definition
afferent input that reaches level of consciousness, sensory information.
Term
somatosensory system
Definition
body surface sensations- skin muscles joints inner ear limb position
Term
special senses
Definition
vision, touch, hearing, taste, smell
Term
transduction
Definition
a receptor functions by converting stimulus energy to an action potential
Term
6 kinds of receptors
Definition
photoreceptors, thermoreceptors, mechanoreceptors, osmoreceptors, chemoreceptors, nociceptors(pain)
Term
types of receptor structure
Definition
either separate cell or modified ending of an afferent neuron. (only smell)
Term
when a receptor is stimulated...
Definition
non selective opening of all small ion channels, net influx of Na+ ions, membrane depolarization, graded potential
Term
conversion of stimulus in modified ending of afferent neuron...
Definition
current flows from one end of afferent neuron to axon of the same, opens Na+ channels, if threshold met, AP occurs.
Term
conversion of stimulus in separate cell
Definition
separate receptor cell stimulated, opens Ca++ channels, increase in Ca++releases chemical messenger. messenger binds to receptor proteins on membrane of afferent axon, Na+ channels open, threshold reached and AP occurs.
Term
ionic receptors
Definition
slow adapting. do not adapt to stimuli, continues to produce AP as stimuli occur.
Term
phasic receptors
Definition
fast adapting, rapidly adapt to stimuli and stop producing AP even though stimuli continue.
Term
what happens to info transmitted by receptor
Definition
receptor causes AP in afferent neurons, afferent AP reaching spinal cord either becomes a reflex or relayed towards the brain. somatosensory pathways relay info to brain through discrete chains of neurons and at any point the pathway activation happens results in sensation.
Term
taste and smell
Definition
chemoreceptors- bind to specific chemicals that generate neural signals.
Term
taste
Definition
taste buds- each taste bud has single opening consisting of 50 receptor cells, each binding sit selectively binds to chemicals, binding of chemical causes depolarization of receptor membrane, initiates AP in afferent neurons.
Term
sour
Definition
acids H+ block K+ which reduces K+ leaking out resulting in depolarization. Ca++ channels open and Ca++ enters. Ca++ causes release of neurotransmitters.
Term
salt
Definition
Na+ moves through Na+ channels to depolarize membrane, depolarization makes Ca++ channels open and Ca++ enters releasing neurotransmitters.
Term
sweet
Definition
glucose bind to the receptor. actives "G protein" which block K+ channels which blocks K+ and depolarizes, depolarizing means Ca++ channels open and Ca++ comes in, releasing neurotransmitter.
Term
bitter
Definition
many chemicals bind to bitter receptor, block K+ which reduces K+ from leaving cell, depolarizing it, which causes Ca++ channels to open and Ca++ to enter, releasing neurotransmitter. (some bitter use G protein)
Term
umami
Definition
amino acids bind to receptor, causes Na+ influx which depolarizes and releases neurotransmitters.
Term
smell
Definition
olfactory receptors, only sense that uses modified afferent neuron ends instead of separate cell. olfactory axons form nerve, receptor cells constantly replaced, each receptor bonds to different components of odor. Na+ and Ca++ cause depolarization and release of neurotransmitters.
Term
vomeronasal organ
Definition
specialized organ in the nose to detect pheromones.
Term
autonomic nervous system
Definition
sympathetic and parasympathetic
Term
autonomic nervous system
Definition
sympathetic and parasympathetic
Term
sympathetic
Definition
activity, overpowering, conscious movement
Term
parasympathetic
Definition
routine housekeeping
Term
somatic nervous system
Definition
voluntary branch; affects skeletal muscle
Term
structure of autonomic nervous system in both sympathetic and parasympathetic
Definition
cell body in CNS axon of 1 connects neuron 2 at ganglion, axon 2 innervates effector organ.
Term
structure in sympathetic only
Definition
originate in thoracic (chest) and lumbar (ab) part of spinal cord. adrenal medulla is modified sympathetic ganglion that secretes hormones into blood when stimulated.
Term
structure in parasympathetic only
Definition
originate in cranial (brain) and sacral (pelvic) areas of CNS. ganglia close to effector organ.
Term
sympathetic neurotransmitters
Definition
1st neuron in chair releases acetylcholine, 2nd releases norepinephrine. adrenal medulla releases mostly epinephrine into blood.
Term
parasympathetic neurotransmitter
Definition
1st neuron releases acetylcholine, 2nd releases acetylcholine
Term
acetylcholine receptors
Definition
located on 2nd neuron in all autonomic and on membrane of effector organs.
Term
norepinephrine and epinephrine receptors
Definition
alpha beta-1 and beta-2 located on effector organs
Term
alpha
Definition
binds norepi causes restriction/contraction
Term
beta-1
Definition
binds norepi and epi equally, found in heart causes stimulation of heart.
Term
beta-2
Definition
binds mostly epi causes relaxation/dialation
Term
are most organs innervated by symp and parasymp?
Definition
yes, they act in opposition to one another.
Term
blood vessels only recieve...
Definition
sympathetic
Term
sweat glands only recieve...
Definition
sympathetic
Term
salivary glands receive...
Definition
both but produce different kinds of saliva
Term
parasympathetic and sympathetic tonic activity
Definition
both active at low levels most of the time.
Term
fight or flight
Definition
sympathetic nervous system- blood vessels constrict, reducing blood flow to digestion. blood vessels in heart dilate. increased heart rate, blood vessels in muscles dilate, airways in lungs dilate, glucose released.
Term
erection
Definition
penis fills with blood, increased pressure restricts veins that drain blood=vasocongestion=erection. controlled by spinal reflex , brain can enhance or inhibit erection.
Term
emission of sperm
Definition
stimulation intensifies, smooth muscle in penis contracts emiting sperm into urethra
Term
expulsion of sperm
Definition
urethra filling with sperm triggers sympathetic response in muscles at base of penis contract and force out semen=orgasm. refractory period after...no orgasm
Term
female sex cycle
Definition
stimuli trigger spinal reflex parasympathetically cause vasodilation of blood vessels in clitoris. brain can inhibit or enhance, vasocongestion causes release of lubricant, tightening, swelling of breasts. uterus raises, sympathetic contraction of pelvic muscle= orgasm, no refractory period.
Term
somatic nervous system
Definition
innervates skeletal muscle
Term
structure of motor neuron
Definition
cell body in ventral horn of spinal cord, axon continues from spinal cord to skeletal muscle, axon terminals release acetylcholine.
Term
neuromuscular junctions
Definition
motor neuron has long myelinated axon, axon divides into many axon terminals at muscle. each axon terminal forms neuromuscular junction with muscle fiber. axon terminal has knob=terminal button. button fits in groove but does not touch motor end plate.
Term
neuromuscular function
Definition
motor neuron action potential reaches terminal. triggers Ca++ channels opening, Ca++ enters, triggers release of acetylcholine from terminal button. Ach binds to motor end plate which causes ion channels to open, lots of Na+ enters, depolarizing=end plate potential, graded potential.Ach then destroyed by enzyme.
Term
endocrine system
Definition
composed of ductless endocrine glands, release hormones inside body, blood transports. specific targets cells respond to specific hormones.
Term
two types of hormones
Definition
tropic and non tropic
Term
tropic hormones
Definition
act on another endocrine gland to produce its hormone
Term
non tropic hormone
Definition
act directly on target cell to produce event
Term
peptides
Definition
small proteins, produced by penial gland, pancreas, GI tract, kidney, liver, thymus, heart. dissolve in water, not fat, transport in blood not plasma
Term
amines
Definition
derived from amino acid tyrosine. tyroid amines T3 and T4, dissolve in fat not water, bound to protein to transport in blood. adrenal medulla- catecholamines (epinephrine and norepinephrine) dissolve in fat not water, bound to protein to transport in blood.
Term
steroids
Definition
derived from cholesterol, produces by adrenal cortex, gonads, placenta during pregnancy. dissolve in fat not water, bound to protein to transport in blood.
Term
hydrophilic hormones
Definition
can not pass through lipid bilayer, bind to membrane receptor, open/close ion channels to change permeability.
Term
lipophilic hormones
Definition
able to pass through lipid bilayer. interact with DNA to alter transcription and produce new proteins.
Term
pineal gland
Definition
in brain, responds to light, produces melatonin, regulates body clock, jet lag drug.
Term
pancreas
Definition
responds to glucose levels in blood. releases insulin promotes uptake of glucose and glucagon promotes increase in blood glucose levels.
Term
hypothalamus and pituitary
Definition
pituitary located at base of hypothalamus. anterior pituitary makes and secretes 6 hormones. hypothalamus produces and releases 7 hormones. regulate via negative feedback.
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