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Chemicals used for long-distance signaling |
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Three Stages of Cell Signaling |
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Reception, Transduction, Response |
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Signal molecule bind to receptor protein causing its shape to change |
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3 main types of membrane receptors |
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1. G protein-coupled receptors 2. Receptor tyrosine kinases 3. Ion channel receptors |
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Receptor Tyrosine Kinases |
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Membrane receptors that attach phosphates to tyrosines |
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2 components of receptor tyrosine kinases |
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1. A Kinase 2.a seperate relay protein |
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Benefits of multiple-step signal transduction |
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-can amplify a signal -more opportunities for regulation |
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Transfer phosphates from ATP to a protein |
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Remove phosphates from proteins |
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an enzyme that converts ATP to cAMP in response to an extracellular signal |
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What cAMP usually activates It phosphorilates other proteins |
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Ways in which intracellular calcium can increase |
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1. facilitated diffusion through ion channels 2. The release of calcium from intracellular stores |
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At each step, the number of activated products is much greater than in the preceding step |
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Large relay proteins to which other relay proteins are attached |
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