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Glycolysis is the _____ phase of ____ _____ |
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1st phase of aerobic respiration |
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Process that partially breaks down glucose and harvests some of its energy |
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Where does Glycolysis occur |
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What organisms does Glycolysis take place in? |
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Beginning equation of Glycolysis Net gain of ATP in Glycolysis |
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Glucose + 2 ATP + 2 NAD+ + 4 ADP + 4Pi Net gain of 2 ATP |
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Step 1 of Glycolysis is called And define |
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Energy investment step ATPs provide enough energy for whole reaction |
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Why would delta G be negative in Glycolysis? Why positive? |
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Negative if ATP is broken down Positive if ATP is built, besides when 1,3 -Bisphosphoglycerate because it is unstable |
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Glyceraldehyde 3-phosphate |
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Dihydroxyacetone phosphate |
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After glucose and before pyruvate in Glycolysis everything is considered an ______ |
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Three irreversible Reactions 1. 3. 10. why random numbers? what do they all have in common |
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1. hexokinase 3. phosphofructokinase 10. pyruvate kinase numbers are what step very negative delta G |
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Why are the three irreversible Glycolysis reactions irreversible |
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Definition
Because them backwards would have a very high delta G |
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Inhibitor for the 3rd step. Feed back inhibition |
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ADP- Hard to say what the three are 1. _____ signals 2. _____ of this = ______ of ______ 3. Activator of ________ |
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Definition
1. Hunger 2. Alot of this = a lot of ATP 3. phosphofructokinase |
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Aresenate What does it affect? What does that ^ cause? |
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Definition
Affects GAP dehydrogenase Prevents Phosphate from being added to sugar |
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Iodoacetate What does it affect? What does that ^ cause? |
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Affects GAP dehydrogenase Covalently binds to active site of enzyme |
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Fluoride ion What does it affect? What does that ^ cause? |
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Affects Enolase Sticks to Mg+2 ion at active site and blocks substrate from entering |
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Where does fermentation take place |
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Fermentation Reaction and why |
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Reaction to recycle NADH to NAD+ in the absence of oxygen So you can still do glycolosis |
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Three steps of Aerobic Respiration 1. 2. Two parts technically 3. |
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Definition
1. Glycolosis 2. Link/Transition Phase & Citric Acid/Krebs Cycle 3. Oxidative Phosphorylation |
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Reactants of Link/Transition Phase 1. 2. 3. |
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Products of Link/Transition Phase 1. 2. 3. |
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Reactants of Krebs Cycle 1. 2. 3. 4. And what to remember about them |
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Acetyl CoA 3NAD+ ADP + P FAD Since Glycolosis produces two pyruvates, they are technically doubled |
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Products of of Krebs Cycle 1. 2. 3. 4. 5. And what to remember about them and where is energy stored? |
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2 CO2 ATP- I think Energy Stored 3 NADH-Energy Stored FADH2-Energy Stored Coenzyme A Since Glycolosis produces two pyruvates, they are technically doubled |
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4 Carbon molecule, last molecule in Krebs cycle before it repeats |
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6 Carbon molecule, first molecule of Krebs cycle after CO2+CoA |
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Concentration gradient potential energy Used in? |
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(Used in Secondary Active Transport) Energy due to concentration gradient |
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Chemical energy Where is energy stored? What two groups of bonds? |
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Definition
Carbon-Carbon bonds High energy phosphate-phosphate bonds Energy stored in bonds |
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Photosynthesis chemical formula |
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Definition
Sun energy + 6H20 + 6 CO2 = C6H12O6 + 6O2 (Chemical energy) |
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Respiration chemical formula |
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Definition
C6H12O6 + 6O2 = 6H20 + 6 CO2 + Chemical Energy (in form of ATP) |
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Anabolic Reactions Two Examples Define |
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Definition
Photosynthesis, Condensation Builds something up & Requires energy |
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Catabolic Reactions Two Examples Define |
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Respiration, Hydrolysis Break something down & Releases Energy |
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First Law of Thermodynamics |
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Law of Conservation of Energy |
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Second Law of Thermodynamics |
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Free energy is the energy available to do work Always decreasing |
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Measure of disorder. Always increasing in a closed system |
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Change from stable to unstable for a change to occur |
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Energy required to get the reactants into an unstable transition state |
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ATP macromolecule category & Type |
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Definition
Nucleic Acid RNA Nucleotide |
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Substrate Level Phosphorylation |
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Take phosphate off ATP & put onto something else to give it energy X + O + ATP =-Enzyme XO + AMP + PPi + light |
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Energy is transferred from one side of the reaction to the other. |
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Extra hydrogens equals ____ _____ |
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Another type of electron carrier besides NAD+ |
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The place on an enzyme where a molecule that is not a substrate may bind, thus changing the shape of the enzyme and influencing its ability to be active. |
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Permanently destroys enzyme, not common in cells |
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Molecules that bond to allosteric sites and support the binding of the substrate at the active site |
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negative delta G spontaneous |
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Positive delta G nonspontaneous |
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Enzyme changes shape slightly as the substrate bonds |
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Substrate bonds to active site and then its bonds are weakened and produces two or more things |
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Inhibitor binding to active site |
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Inhibitor binding to allosteric site thus changing shape of enzyme |
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Resulting equation of Glycolysis What is used in Krebs/Link |
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2 pyruvates + 2 ADP + 2Pi + 4 ATP + 2NADH Pryuvates used in Link/Krebs Cycle becomes Acetyl CoA which is used in Krebs |
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Lactic Acid Fermentation Equation |
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2 Pyruvic acid + 2 NADH + 2H+ = 2NAD+ + 2 Lactic Acid |
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Alcohol Fermentation Equation |
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2 Pyruvic acid have 2 CO2 removed to become Acetaldehyde THEN 2 Acetaldehyde 2 NADH + 2H+ = 2NAD+ + 2Ethanol |
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Where does Transition Phase occur |
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Reactants of Oxidative Phosphorylation 1. 2. 3. 4. 5. |
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3ADP 3Pi NADH 1/2 O2 Bunch of H+ |
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Products of Oxidate Phosphorylation 1. 2. 3. 4. 5. |
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ATPs made from all Aerobic Respiration How many in Glycolysis? How many in Link How many in Krebs How many in Oxidative |
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Definition
36 total net of 2 from Glycolysis 0 from link 2 from Krebs 32 from Oxidative |
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How many NADH and FADH in: Glycolysis Link Krebs |
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Definition
2 NADH in Glycolysis 2 NADH in Link 6 NADH and 2 FADH2 in Krebs |
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How many ATPs do NADH produce How many ATPs do FADH2 produce How many ATPs do the 2 NADHs from Glycolysis make |
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NADH= 3 ATP FADH2= 2 ATP NADH from Glycolysis= 2 ATP due to passing though mitochondrion membrane |
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Electron Transport chain Two things that occur and where Well three sort of |
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Definition
NADH = NAD+ occur on integral membrane protein FADH2 = FAD+ Integral membrane protein DIFFERENT then the NADH Oxygen collects e- and becomes water and the hydrogen goes to ATP synthase |
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Yeast does ____ fermentation Humans do _____ fermentation |
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Definition
Yeast does Ethanol Fermentation Humans do Lactic Acid Fermentation |
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Oxidative puts NADH to NAD+ while _______ does so as well but without something |
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Fermentation does so without oxygen |
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