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Chapter 8 Bio
N/A
50
Biology
Undergraduate 3
10/16/2013

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Term
Cells extracts energy..
Definition
and applies energy to perform work
Term
An organism metabolism does what?
Definition
Transforms matter and energy.
Term
Metabolism
Definition
totality of an organisms chemical reactions
Term
Metabolic Pathway
Definition
Begins with a specific molecule
Ends with a product

(Specific Molecule)A->B->C->D(Product)
Term
Catabolic Pathway
Definition
Release energy
Term
Anabolic Pathways
Definition
Consume energy
Term
Bio energetic
Definition
study of how organisms manage their energy resources
Term
Energy
Definition
is the capacity to cause change
Term
Kinetic Energy
Definition
energy associated with motion
Term
Potential Energy
Definition
Energy that matter possesses b/c of its location or structure
Term
Chemical Energy
Definition
potential energy available for release in a chemical reaction
Term
1st Law of Thermodynamics
Definition
The energy in the universe is constant. It cannot be created nor destroyed.
Term
2nd Law of Thermodynamics
Definition
Every energy transfer or transformation increases that Entropy (disorder) of the universe.
Term
The Free-Energy change of a reaction tell us?
Definition
Whether or not the reaction occurs spontaneously
Term
Delta G=Delta H + (T) Delta S
Definition
Delta G = change in the free-energy
Delta H = change in total energy
Delta S = change in entropy
T = Temperature
Term
Free-Energy?
Definition
measure of a system's instability
Term
Whats happens in a spontaneous change?
Definition
Free-energy decreases + stability increases
Term
Equilibrium
Definition
is a state of maximum stability .

Btw - cell are not equilibrium
Term
Exergonic Reaction
Definition
Release of Free-Energy + Is Spontaneous
Term
Endergonic Reaction
Definition
absorbs + is non-spontaneous
Term
What are the 3 main kinds of work for a cell?
Definition
Chemical + Mechanical + Transport
Term
To do work, Cells manage energy resources by release of ?
Definition
Energy Coupling
Term
Energy Coupling
Definition
is mediated by ATP
Term
ATP
Definition
Adenosine Triphopshate , is the cells energy shuttle.
Term
What is ATP composed of?
Definition
Ribose (sugar)
Adenine (nitrogen base)
3 phosphate groups
Term
Energy is released when?
Definition
the terminal phosphate bond is broken
Term
Hydrolysis
Definition
Can break down ATP's tails between the phosphate group
Term
The 3 main work of a cell is powered by?
Definition
The hydrolysis of ATP
Term
How do the Hydrolysis of ATP perform work?
Definition
In the cell, the energy from the Exergonic reaction of ATP hydrolysis can be used to drive an Endergonic reaction.

Overall the coupled reactions are Exergonic.
Term
ATP drives Endergonic reactions by?
Definition
Phosphorylation, transferring a phospahte group to some other molecule, such as a reactant.
Term
Phosphorylated Inteermediate
Definition
Recipient molecule
Term
How does ATP regenerate?
Definition
ATP regenerate by addition of a P group to adenosine diP (ADP)
Term
How is ATP a cycle that is like a revolving door?
Definition
Energy passes during its tranfer from Carabolic to Anabolic pathways
Term
Enzymes speed up metabolic reaction by?
Definition
Lowering energy barrier
Term
Catalyst
Definition
a chemical agent that SPeed UP reaction and not consume.
Term
Enzyme
Definition
a Catalytic Protein
Term
An example of a Enzyme
Definition
Hydrolysis of sucrose by the enzyme sucrose
Term
The initial energy needed to start a chemical reaction is called?
Definition
Activation Energy (Ea) or free energy of activation
Term
How is Activation energy supplied and what kind of form is it?
Definition
Activation Energy is supplied by the molecule which absorbs thermal energy.
Term
How does Enzymes lower the Ea Barrier?
Definition
Enzymes catalyze the reactions by lowering the Ea Barrier. They do not affect the change in free energy.
Term
Reactant that Enzyme acts on is?
Definition
Enzyme's substtrate
Term
Enzyme that binds to its substrate is called?
Definition
Enzyme-substrate Complex
Term
Active Site
Definition
region on enzyme where substrate binds
Term
Induced fit
Definition
a substrate brings chemical groups of active site into position that enhance their ability to catalyze reaction
Term
What are the four ways Active site can lower an Ea barrier by?
Definition
Orienting substrates correctly
Straining substrate bonds
Providing a favorable microenvironment
Covalently bonding to the substrate
Term
What can affect an enzyme's activity?
Definition
General environment
Chemical that specifically influence the enzymes
Term
Cofactors?
Definition
Are nonprotein enzymes helpers.

It can also be inorganic
Term
Coenzyme
Definition
organic cofactor
Term
Competitive inhibitors
Definition
Bind to active site of enzyme
Term
Noncompetitive inhibitors
Definition
bind to another part of enzymes
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